McGeer and Associates Laboratory
Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver Canada

Publications of McGeers in the Kinsmen Laboratory


803. Jantaratnotai N, McGeer PL, McLarnon JG. Mechanisms of Mg2+ inhibition of
BzATP-dependent Ca2+ responses in THP-1 monocytes. Brain Res 1442, 1-8, 2012

802.  Lee M, Guo J-P, Schwab C, McGeer EG, McGeer PL. Selective inhibition of the membrane
attack complex of complement by low molecular weight components of the aurin tricarboxylic acid
synthetic complex. Neurobiol Aging doi:10.1016/j.neurobiolaging.2011.12.005

801. Schwab C, Yu S, McGeer EG, McGeer PL. Optineurin in Huntington’s disease intranuclear
inclusions. Neurosci Lett, 506/1, 149-54, 2012 doi:10.1016/j.neulet.2011.10.070

800. Schwab C, Yu S, McGeer PL. Optineurin is colocalized with ubiquitin in marinesco bodies.
Acta Neuropathol. 123/2(12)289-92 DOI 10:1007/s00401-011-0915-y, 2012

799. Lee M, Kang Y, Suk K, Schwab C, Yu S, McGeer, PL. Acidic fibroblast growth factor potentiates
glial-mediated neurotoxicity by activating FGFR2 IIIb. J Biol Chem 286, 41230-41245, 2011

798. Jantaratnotai N, Ryu JK, Schwab C, McGeer PL, McLarnon JG. Comparison of vascular
perturbations in an Ab-injected animal model and in AD brain.
Int J Alz Dis 2011, Article 918280,
8 pages. Doi:10.4061/2011/918280

797. Lee M, McGeer EG, McGeer PL. Mechanisms of GABA release from human astrocytes.
Glia 59:1600-1611, 2011.

796. Lee M, Kwon B-M, McGeer E, McGeer PL. Effects of obovatol on GSH-depleted glia-mediated
neurotoxicity and oxidative damage. J Neuroimmune Pharm DOI 10.1007/s11481-011-9300-9 (2011)

795. Lee M, Suk K, Kang Y, McGeer E, McGeer PL. Neurotoxic factors released by stimulated human
monocytes and THP-1 cells. Brain Res 1400:99-111, 2011.

794. McGeer PL, Steele JC. The ALS/PDC syndrome of Guam: Potential biomarkers for an enigmatic
disorder. Prog Neurobiol 201. doi:10.1016/j.pneurobio.2011.04.001.

793. Hashioka S, Klegeris A, McGeer PL. Proton pump inhibitors reduce interferin-g induced neurotoxicity
and STAT3 phosphorylation of human astrocytes. Glia 59:833-840, 2011.

792. Zou W-Q, Xiao X, Yuan J and 17 others including McGeer PL. Amyloid b42 interacts mainly with
insoluble prion protein in the Alzheimer’s brain. J Biol Chem 286:15095-15105, 2011,
published 3/10/11 as manuscript M110.199356 on line

791. Lee M, McGeer PL. Weak BMAA toxicity compared with that of the dietary supplement beta-alanine.
J Neurobiol Aging 1011. doi:10.1016/j.neuobiolaging.2010.11.024.

790. Lee M, Jantartnotai N, McGeer E, McLarnon JG, McGeer PL. Mg2+ ions reduce microglial and
THP-1 cell neurotoxicty by inhibiting Ca2+ entry through purinergic channels. Brain Res 1369:21-35, 2011.
doi:10.1016/j.braubres.2010.10.084.

789. Ryu JK, Jantartnotai N, Serrano-Perez MC, McGeer PL, McLarnon JG. Block of purinergic P2X7R
inhibits tumor growth in a c6 glioma brain tumor animal model. J Neuropathol Exp Neurol 70:13-22, 2011.

788. Hashioka S, Klegeris A, Qing H, McGeer PL. STAT3 inhibitors attenuate interferon-g induced
neurotoxicity and inflammatory molecule production by human astrocytes.

Neurobiol Dis 41:297-310, 2011. doi:10.1016/j.nbd.2010.09.018.

787. Lee M, Schwab C, McGeer PL. Astrocytes are GABAergic cells that modulate microglial activity.
Glia 59:152-165, 2011.

786. McGeer PL, McGeer EG. History of innate immunity in neurodegenerative disorders. Frontiers in
Pharmacology, Nov 2011, vol 2, 1-6. www.frontiersin.org.

785. Hashioka S, Klegeris A, Schwab C, Yu S, McGeer PL. Differential expression of interferon-g receptor on
human glial cells in vivo and in vitro. J Neuroimmunol 225:91-99, 2010.

784. Jantaratnotai N, Schwab C, Ryu JK, McGeer PL, McLarnon JG. Converging perturbed microvasculature and
microglial clusters characteriza Alzheimer disease brain.
Curr Alz Res 7:625-636, 2010.

783. Lee M, Tazzari, Giustarini D, Rossi R, Spartore A, Del Soldato P, McGeer E, McGeer PL. Effects
of hydrogen sulfide-releasing L-DOPA derivatives on glial activation. J Biol Chem 285:17318-17328, 2010.

782. Morawski M, Hartlage M, Jager C and 7 others including McGeer PL. Distinct glutaminyl cyclase
expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basilis Meynert contributes to
pGlu-Ab pathology in Alzheimer’s disease. Acta Neuropathol 120/2:195-207, 2010

781. Guo J-P, Yu S, McGeer PL. Simple in vitro assays to identify amyloid-b aggregation blockers for
Alzheimer’s disease therapy. J Alz Dis 19:1359-1370, 2010.

780. Lee M, Cho T, Jantaratnotai N, Wang YT, McGeer E, McGeer PL. Depletion of GSH in glial cells induces
neurotoxicity: relevance to aging and degenerative neurological diseases. The FASEB J 24:2533-2540, 2010.

779. Zou W-Q and 19 others including McGeer PL. PrP conformational transitions alter species-preference of
a PrP specific antibody. J Biol Chem 285:13874-13884. 2010. Published on line March 1, 2010.

778. Steele JC, McGeer PL, Miklossy J. Amyotrophic lateral sclerosis/Parkinsonism-dementia complex of three
Pacific isolates. Encyclopedia of Movement Disorders, Kompoliti K, Verhagen Metman L, eds. 1:39-45, 2010.
Oxford University Press.

777. Villoslada P and 16 others including McGeer PL. Immunotherapy for neurological disease.
Clin Immunol 128:294-305, 2008.

776. Schwab C, Klegeris A, McGeer PL. Inflammation in transgenic models of neurodegenerative disorders.
Biochem Biophys Res Commun 1802:889-892, 2010. doi:10.1016/j.bbadis.2009.10.013.

775. Qing H, Zhang Y, Deng Y, McGeer EG, McGeer PL. Lrrk2 interaction with a-synuclein in diffuse Lewy
body disease. Biochem Biophys Res Commun 390:1229-1234, 2009. doi:10.1016/j.bbrc.1009.10.126.

774. McGeer EG, McGeer PL. Neuroinflammation in Alzheimer’s disease and mild cognitive impairment:
A field in its infancy. J Alz Dis 18:231-236, 2009.

773. McGeer PL, Kornelsen R, McCormick S, Ferreira C, Lapi S, Ruth TJ. PET imaging reveals that entanercept
crosses the blood-cerebrospinal fluid but not the blood-brain barrier: Implications for Alzheimer disease.

J Alz Dis 18:231-236, 2009.

772. Lee M, Schwab C, Yu S, McGeer E, McGeer PL. Astrocytes produce the antiinflammatory and
neuroprotective agent hydrogen sulfide. Neurobiol Aging 30:1523-1534, 2009.
doi:10.1016/j.neurobiolaging.2009.06.001.

771. Qing H, Wong W, McGeer EG, McGeer PL. Lrrk2 phosphorylates alpha-synuclein at serine 129: parkinson’s
disease implications.
Biochem Biophys Res Commun 387:149-152, 2009.

770. Lee M, Spartore A, Del Soldato P, McGeer E, McGeer PL. Hydrogen sulfide releasing NSAIDs attenuate
neuroinflammation induced by microglial and astrocytic activation. Glia 58:103-113, 2009. 10.1002/glia.20905.

769. Hashioka S, McGeer PL. Complexity of microglial activation state: can modifying microglial activation treat
Alzheimer’s disease? Future Neurol 4:137-139, 2009.

768. Hashioka S, McGeer PL, Monji A. Anti-inflammatory effects of antidepressants: possibilities for preventives against
Alzheimer’s disease. Central Nerv Syst Agents in Med Chem 9:12-19, 2009.

767. Schwab C, Arai T, Hasegawa M, Akiyama H, Yu S, McGeer PL. TDP-43 pathology in familial British dementia.
Acta Neuropath 118:303-311, 2009.

766. Hashioka S, Klegeris A, McGeer PL. Proton pump inhibitors exert anti-inflammatory effects and decrease human
microglial and monocytic cell neurotoxicity. Exp Neurol 217:111-183, 2009. doi:10.1016/j.expneurol.2009.02.002.

765. Ludolph A, Kassubek J, Landwehrmeyer BG et al. (including McGeer PL). Tauopathies with parkinsonism:
clinical spectrum, neurologic basis, biological markers and treatment options. Eur J Neurol 16:297-309, 2009.
doi:10.1111/j.1468-1331.2008.02513x.

764. McGeer PL, McGeer EG, Schwab C. Inflammatory processes exacerbates degenerative neurological disorders.
In: Current Hypotheses and Research Milestones in Alzheimer’s Disease, Maccioni RB, Perry G, eds. Springer
Science + Business Media, 2009. doi:10.1007/978-0-387-87995-6_10.

763. McGeer PL. Amyloid-b vaccination for Alzheimer’s dementia. Letter to the editor. Lancet 372:1381, 2008.

762. Steele JC, McGeer PL. The ALS/PDC syndrome of Guam and the cycad hypothesis. Neurology 70:1984-1990, 2008
and reply by authors.

761. Hamo H, Kiriyama Y, Mizoe A, Murase E, Okajima S, Akiguchi I, Hirasawa Y, McGeer PL. A computer support system
for neurological anatomical diagnosis. Clin Neurol Neurosurg 110:973-978, 2008.

760. Miklossy J, Kasas S, Zurn AD, McCall S, Yu S, McGeer PL. Persisting atypical and cystic forms of Borrealia
        burgdorferi and local inflammation in Lyme neuroborreliosis. J Neuroinflamm 5, 2008
759. Steele JC, McGeer PL. The ALS/PDC syndrome of Guam and the cycad hypothesis. Neurology 70:1984-1990, 2008.
758. Wszolek ZK, Zimprich A, Biskup S et al (including McGeer PL as last author). LRRK2 (Leucine-Rich Repeat Kinase 2)
        gene on PARK8 locus in families with Parkinsonism. In Advances in Alzheimer's and Parkinson's Disease: Insights,
        Progress and Perspectives (Eds A Fisher et al. Spronger, 2008, pp 75-89
757. McGeer EG, McGeer PL. Neuroinflammation. Alzheimer Disease, and other aging disorders. In: Pharmacological
        Mechanisms in Alzheimer's Disease. AC Cuello, ed. Springer, NY, 2008, pp 149-166
756. Miklossy J, Qing H, Radenovic A, Kis A, Vileno B, Laszlo F, Miller L, Martins RN, Waeber G, Mooser V, Bosman F,
        Khalili K, Darbinian-Sarlissian N, McGeer PL. Beta amyloid and hyperphosphorylated tau deposits in the pancreas in
        type 2 diabetes. Neurobiol Aging 2008. doi:10.1016/j.neurobiolaging.2008.08.019
755. Schwab C, Arai T, Hasegawa M, Yu S, McGeer PL. Colocalization of TDP-43 and Huntingtin in inclusions of 
        Huntington's disease. J Neuropath Exp Neurol 67:1159-1165, 2008
754. McGeer PL, Amyloid-b vaccination for Alzheimer's dementia. Lancet 372:1381, 2008
753. Miklossy J, Martins R, Darbinian N, Khalili K, McGeer PL. Type 2 diabetes: local inflammation and direct effect of 
        bacterial toxic components. Open Path J 2:86-95, 2008
752. Gnjec A, D'Costa KJ, Laws SM, Hedley R, Balakrishnan K, Taddei K, Martins G, Paton A, Verdile G, Gandy SE,
        Broe GA, Brooks WS, Bennett H, Piguet O, Price P, Miklossy J, Hallmayer J, McGeer PL. Martins RN, Association
        of alleles carried at TNFA-850 and BAT1-22 with Alzheimer's disease. J Neuroinflamm 2008, 5:36 doi:10.1186/1742-
        2094-5-36
751. Hashioka S, Klegeris A, Schwab C, McGeer PL. Interferon-g-dependent cytotoxic activation of human astrocytes and
        astrocytoma cells. Neurobiol Aging (2008), doi:10.1016/j,neurobiolaging.2008.02.019
750. Hashioka S, Miklossy J, Schwab C, Klegeris A, McGeer PL. Adhesion of exogenous human microglia and THP-1 cells
        to amyloid plaques of postmortem Alzheimer's disease brain. J Alz Dis 14:345-352, 2008
749. McGeer PL, McGeer EG. Glial reactions in Parkinson's disease. Movement Dis 23:474-483, 2008.
748. Yuan J, Dong Z, Guo J-P, Xiao X, Wang J, McGeer PL, Cashman NR, Bessen R, Surewicz WK, Kneale G, Petersen
        RB, Gambetti P, Zou WQ. Accessibility of a critical prion protein region involved in strain recognition and its implications
        for the early detection of prions. Cell Mol Life Sci 2008 (13 pages)
747. Klegeris A, Pelech S, Giasson BI, Maguire J, Zhang H, McGeer EG, McGeer PL. a-Synuclein activates stress signaling
        protein kinases in THP-1 cells and microglia. Neurobiol Aging 29:730-752, 2008.
746. Winkler DFH, McGeer PL. Protein labeling and biotinylation of peptides during spot synthesis using biotin p-nitrophenyl
        ester (biotin-ONp). Protomics 8:961-967, 2008
745. Klegeris A, Li J, Bammler TK, Jin J, Zhu D, Kashima DT, Pan S,, Hashioka S, Maguire J, McGeer PL, Zhang J. Prolyl
        endopetidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP-1 cell 
        neurotoxicity. Glia 56:675-685, 2008
744. Steele JC, McGeer PL. The ALS/PDC syndrom of Guam and the cycad hypothesis. Neurology 70:1984-90, 2008
743. Schwab S, McGeer PL. Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders. J Alz Dis
        13:359-369, 2008
742. McGeer PL, McGeer EG. The a-synuclein burden hypothesis of Parkinson disease and its relationship to Alzheimer
        disease. Exp Neurol 212:235-238, 2008
741. Klegeris A, McGeer PL. Complement activation by islet amyloid polypeptide (LAPP) and a-synuclein 112. Biochem
        Biophys Res Commun 357:1096-9, 2007;
740. Klegeris A, McGeer EG, McGeer PL. Therapeutic approaches to inflammation in neurodegenerative disease. Curr Opin
        Neurol 20:351-357, 2007
739. Hashioka S, Klegeris A, Monji A, Kato T, Sawada M, McGeer PL, Kanba S. Antidepressants inhibit interferon-g-
        induced microglial production of IL-6 and nitric oxide. Exp Neurol 206:33-42, 2007
738. Klegeris A, Choi HB, McLarnon JG,McGeer PL. Functional ryanodine receptors are expressed by human microglia and
        THP-1 cells: their possible involvement in modulation of neurotoxicity. J Neurosci Res 85:2207-2215, 2007
737. Zhang W, Dallas S, Zhang D, Guo J-P, Wilson B, Miller DS, Chen B, Zhang W, McGeer PL, Hong J-S, Zhang J.
        Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and
        A53T mutant alpha-synuclein. Glia 55:1178-1188, 2007
736. Miklossy J, Qing H, Guo J-P, Yu S, Wszolek ZK, Calne D, McGeer EG, McGeer PL. Lrrk2 and chronic inflammation
        are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation. Acta Neuropathol 114:243-254, 2007
735. McGeer EG, McGeer PL. The role of anti-inflammatory agents in Parkinson's disease. CNS Drugs 2:789-797, 2007
734. McGeer PL, McGeer EG. NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies. Neurobiol
        Aging 28:639-647, 2007
733. Wszolek ZK, Baba Y, Mackenzie IR, Uitti RJ, Strongosky AJ, Broderick DF, Baker MC, Melquist S, Hutton ML,
        Tsuboi Y, Allanson JE, Carr J, Kumar A, Calne SM, Miklossy J, McGeer PL, Calne DB, Stoessl J. Autosomal
        dominant dystonia-plus with cerebral calcifications. Neurology 67:1-6, 2006
732. Calne SM, Miklossy J, McGeer PL, Calne DB, Stoessl J. Autosomal dominant dystonia-plus with cerebral calcifications.
        Neurology 67:1-6, 2006
731. Patrick DM, Petric M, Skowronski DM, Guasparini R, Booth EF, Krajden M, McGeer P, Bastien N, Gustafson L,
        Dubord J, MacDonald D, David ST, Srour LF, Parker R, Andonov A, Isaac-renton J, Loewen N, McNabb G, McNabb
        A, Goh S-H, Henwick S, Astell C, Guo JP, Drebot M, Tellier R, Plummer F, Brunham RC. An outbreak of human
        coronavirus OC43 infection and serological cross-reactivity with SARS coronavirus. Can J Infect Dis Med Microbiol
        17:330-336, 2006
730. Miklossy J, Arai T, GuoJ-P, Klegeris A, Yu S, McGeer EG, McGeer PL. LRRK2 expression in normal and pathologic
        human brain and in human cell lines. J Neuropath Exp Neurol 65:953-963, 2006
729. Klegeris A, Giasson BI, Zhang H, Maguire J, Pelech S, McGeer PL. Alpha-synuclein and its disease causing mutants
        induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells. FASEB J 20:2000-2008, 2006
728. Klegeris A, Schulzer M, Harper DG, McGeer PL. Increase in core temperature of Alzheimer's disease patients as a
        possible indicator of chronic neuroinflammation: a meta analysis. Gerontology 53:7-11, 2006
727. Miklossy J,Doudet D, Schwab C, Yu S, McGeer E, McGeer PL. Role of ICAM-1 in persisting inflammation in
        Parkinson's disease. Exp Neurol 197:275-283, 2006
726. Guo J, Arai T, Miklossy J, McGeer PL. A-beta and tau form soluble complexes that may promote self-aggregation of
        both into the insoluble forms observed in Alzheimer disease. Proc Natl Acad Sci USA 103:1953-1958, 2006
725. McGeer EG, Klegeris A, McGeer PL. Inflammation, the complement system and the diseases of aging. Neurobiol Aging
        26S:S94-S97, 2005
724. Arai T, Miklossy J, Klegeris A, Guo J-P, McGeer PL. Thrombin and prothrombin are expressed by neurons and glial
        cells and accumulate in neurofibrillary tangles in Alzheimer's disease. J Neuropath Exp Neurol 65:19-25, 2006
723. McGeer PL, Rogers J, Miklossy J, McGeer EG, Inflammation, antiinflammatory agents and Alzheimer diseae: The last 12 
        years J Alz Dis & Related Dis 9:271-6, 2006
722. McGeer PL, McGeer EG. The pivotal role of complement in neurodegenerative diseases. In Current Topics in
        Neuroimmunology, Medimond Secretariat (ed T Tabira et al) from 8th Intl Congress on Neuroimmunology, Japan 2006,
        pp 147-151
721. Miklossy J, Rosenberg S, McGeer PL. Beta amyloid deposition in the atrophic form of general paresis. In: Alzheimer's 
        Disease: New advances, eds Iqbal K, Winblad B, Avila J, MEDIMOND S.r.l., Bologna, Italy, 2006, pp 429-433
720. McGeer EG, McGeer PL. Inflammation and the lesions of Alzheimer disease. In: Alzheimer: 100 Years and Beyond,
        Jucker et al. eds. Springer-Verlag Berlin Heidelberg 2006, pp 413-416
719. McGeer PL, Sibley J. Sparing of age related macular degeneration in rheumatoid arthritis. Neurobiol Aging 27:1533-
        1534, 2006
718. Miklossy J, Calne DB, Wszolek ZK, Mackenzie IR, Dorovini-Zis K,McGeer PL. Severe vascular disturbance in a case
        of familial brain calcinosis. Acta Neuropath 109:643-653, 2005
717. Stoessl AJ, McGeer PL. Hot spots: Can PET offer insights into the pathogenesis of Parkinson's disease? Ann Neurol 
        57:162-2, 2005
716. McGeer EG, McGeer PL, Abeta immunotherapy and other methods of reducing amyloid, Current Drug Targets - CNS
        & Neurological Disorders 4:569-573, 2005
715. Klegeris A, McGeer PL. Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the
        treatment of neurodegenerative disease. Curr Alz Research 2:355-365, 2005
714. Klegeris, A. and McGeer, P.L. Chymotrypsin-like proteases contribute to human monocytic THP-1 cell, as well as
        microglial neurotoxicity. Glia 51:56-64, 2005
713. Arai T, Guo JP, McGeer PL, Proteolysis of non-phosphorylated and phosphorylated tau by thrombin. J. Biol. Chem
        280:5145-53, 2005
712. Klegeris A, Bissonette C, McGeer PL, Modulation of human microglia and THP-1 cell neurotoxicity by cytokines
        endogenous to the nervous system, Neurobiol Aging 26:673-682, 2005
711. McGeer EG, McGeer PL, Role of neural-immune interactions in neurodegenerative diseases, In Clinical
        Neuroimmunology, 2nd ed., Antel J, Birnbaum G, Hartung H-P. Vincent A, eds. Oxford University Press, 2005, pp 355-
        363
710. McGeer EG, McGeer PL, Pharmacological approaches to the treatment of amyotrophic lateral sclerosis, BioDrugs 19:31-
        37, 2005
709. Morris HR, Steele JC, Crook R, Wavrant-De Vrieze F, Onstead-Cardinale L, Gwinn-Hardy K, Wood NW, Farrer M,
         Lees AJ, McGeer PL, Siddique T, Hardy J, Perez-Tur J. Genome-wide analysis of the parkinsonism-dementia complex
         of Guam. Arch Neurol 61:1889-97, 2004
708. Zhang X-j, McGeer PL. The expression of complement receptor type 2(CR2) in brain tissue of patients with Alzheimer's
        disease. Chin J Geriatr 23:387-390, 2004
707. Hosokawa M, Klegeris A, McGeer PL. Human oligodendroglial cells express low levels of C1 inhibitor and membrane
        cofactor protein mRNAs. J Neuroinfllammation 1:17-24, 2004
706. Klegeris A, Maguire J, McGeer PL. S- but not R-enantiomers of flurbiprofen and ibuprofen reduce human microglial and
        THP-1 cell neurotoxicity. J Neuroimmunol 152:73-77, 2004
705. Guo J-P, Petric M,Campbell W, McGeer PL. SARS corona virus peptides recognized by antibodies in the sera of
        convalescent patients. Virology 324:251-256, 2004
704. Bissonnette CJ, Klegeris A, McGeer PL, McGeer EG. Interleukins IL-1a and IL-6 protect human neuronal SH-SY5Y
        cells from oxidative damage. Neurosci Lett 361:40-43, 2004
703. Schwab C, Hosokawa M, McGeer PL, Transgenic mice overexpressing amyloid beta protein are an incomplete model of
        Alzheimer disease. Exp Neurol 188:52-64, 2004
702. Akiyama H, McGeer PL. Specificity of mechanisms for plaque removal after Ab immunotherapy for Alzheimer disease.
        Nature Med 10:117-8, 2004.
701. McGeer PL, McGeer EG, Inflammation and the degenerative diseases of aging, Ann NY Acad Sci. 1035:104-116, 2004

700. McGeer PL, McGeer EG. Immunotherapy for Alzheimer's disease. SAGE KE (sageka.sciencemag.org) Sci Aging
        Knowl Environ, 2004, 5 pages
699. McGeer PL, McGeer EG, Inflammation and neurodegeneration in Parkinson's disease. .Parkinsonism and Related
        Disorders 10:S3-S7, 2004
698. McGeer EG, McGeer PL. Neural inflammatory mechanisms in Alzheimer's disease. In: Dementia, Presentations,
        Differential diagnosis and nosology, 2nd edition, The John Hopkins University Press, 2003, pp 121-138
697. Akiyama H, Kondo H, Arai T, Ikeda K, Kato M, Iseki E, Schawb C, McGeer PL. Expression of BRI, the normal
         precursor of the amyloid protein of familial British dementia, in humn brain. Acta Neuropathol 107:53-58, 2003
696. McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after MPTP
        administration, Ann Neurol 54:599-604, 2003
695. Klegeris A, McGeer PL. Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells
        is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP. J Leukoc Biol 73:369-378, 2003
694. Klegeris A, Bissonnette CJ,, McGeer PL. Reduction of human monocytic cell neurotoxicity and cytokine excretion by
        ligands of the cannabinoid-type CB2 receptor. Brit J Pharmacol 139:775-786, 2003
693. Hosokawa M, Klegeris A, Maguire J, McGeer PL. Expression of complement messenger RNAs and proteins by human
        oligodendroglial cells. Glia 42:417-23, 2003
692. Schwab C, Hosokara M, Akiyma H, McGeer PL. Familial British dementia; contribution of furin and ABri amyloid. Acta
        Neuropathol 106:278-284, 2003
691. McGeer PL, McGeer EG. Is there a future for vaccination as a treatment for Alzheimer's disease? Neurobiol Aging
        24:391-395, 2003
690. McGeer EG, McGeer PL. Inflammatory processes in Alzheimer;s disease. Progr Neuro-Psychopharmacol & Biol 
        Psychiatry 27:741-9, 2003
689. McGeer EG, McGeer PL. Clinically tested drugs for Alzheimer's disease. Expert Opin Investig Drugs 12:1143-51, 2003
688. McGeer PL, McGeer EG. Local neuroinflammation and the progression of Alzheimer's disease. J Neurovirol 8:529-538, 
        2002
687. McGeer PL, McGeer EG. Inflammatory processes in amyotrophic lateral sclerosis. Muscle & Nerve 26:459-470, 2002
686. Klegeris A, Liutkevicius E, Mikalauskiene G, Duburs G, McGeer PL, Klusa V. Anti- inflammatory effects of cerebrocrast
        in a model of rat paw edema and on mononuclear THP-1 cells. Eur J Pharmacol 441:203-208. 2002
685. Klegeris A, Singh EA, McGeer PL. Effects of C-reactive protein and pentosan polysulphate on human complement
        activation. Immunology 106, 381-388, 2002
684. Klegeris A, McGeer PL, Cyclooxygenase and 5-lipoxygenase inhibitors protect against microglial neurotoxicity,
        Neurobiol Aging 23, 789-796, 2002
683. McGeer PL, Yasojima K, McGeer EG. Association of interleukin-1b polymorphisms with idiopathic Parkinson's disease.
        Neurosci Lett 326:67-69, 2002
682. McGeer PL, McGeer EG, Yasojima K. Expression of COX-1 and COX-2 mRNAs in atherosclerotic plaques. Exp
        Geront 37, 925-929, 2002
681. Wakita H, Tomimoto H, Akiguchi I, Matsuo A, Lin J-X, Ohara M, McGeer PL. Axonal damage and demyelination in the
        white matter after chronic cerebral hypoperfusion in the rat. Brain Res 924, 63-70, 2002
680. Schwab C, McGeer PL. Complement activated C4d immunoreactive oligodendrocytes delineate early plaques in multiple
        sclerosis' Exp Neurol 174, 81-88, 2002
679. McGeer PL, McGeer EG. Innate immunity, local inflammation, and degenerative disease. AAAS/SAGE.KE.
         http://sageke.sciencemag.org/cgi/content/full/sageke;2002/29/re3
678. McGeer PL, McGeer EG. The possible role of complement activation in Alzheimer disease. Trends Mol Med 8: 519-523,
        2002
677. Yasojima K, McGeer EG, McGeer PL. Relationship between beta amyloid peptide Generating molecules amd neprilysin
         in Alzheimer disease and normal brain, Brain Res 919:115-121, 2001
676. Yasojima K, McGeer EG, McGeer PL. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and 
         control brain, Neuroreport 12, 2935-2938 (2001)
675. Yasojima K, McGeer EG, McGeer PL, High stability of mRNAs postmortem and protocols for their assessment by RT-
         PCR, Brain Res Protocols 8:212-218, 2001
674.  McGeer EG, Yasojima K, Schwab C, McGeer PL. The pentraxins: possible role in Alzheimer's disease and other
         inflammatory disorders. Neurobiol Aging 22:843-848, 2001
673. McGeer PL, McGeer EG. Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 22:799-809, 2001
672. Morris HR, Al-Sarraj S, Schwab C, Gwinn-Hardy K, Perez-Tur J, Wood NW, Hardy J, Lees AJ, McGeer PL, Daniel
        SE, Steele JC. A clinical and pathological study of motor neurone disease on Guam. Brain 124:2215-2222, 2001
671. McGeer PL, McGeer EG. Polymorphisms in inflammatory genes enhance the risk of Alzheimer disease, Arch Neurol 
        58:1790-1792, 2001
670. Klegeris A, McGeer PL. Inflammatory cytokine levers are influenced by interactions between THP-1 monocytic, U-373
        MG astrocytic, and SH-SY5Y neuronal cell lines of human origin. Neurosci lett 313:41-44, 2001
669. Yasojima, Schwab C, EG McGeer, PL McGeer, Complement components, but not the complement regulators C1
         inhibitor and CD59, are upregulated in atherosclerotic plaques. Arterioscler Thromb Vasc Biol 21:1214-1219, 2001
668. Yasojima K, McGeer EG, McGeer PL. Increased cyclooxygenase-2 mRNA in ALS spinal cord, Neurology 57, 952-
         956, 2001
667. Klegeris A, Schwab C, McGeer PL. Induction of complement C9 in human neuronal cells by inflammatory stimuli:
        relevance to neurodegenerative disorders. Exp Geront 36, 1179-1188, 2001
666. Akiyama H, Kondo H, Ikeda K, Kato M,, McGeer PL.Immunohistochemical localization of neprilysin in the human
        cerebral cortex: inverse association with vulnerability to amyloid b-protein (Ab) deposition. Brain Res 901, 277-281, 2001
665. McGeer PL,Yasojima K, McGeer EG.Inflammation in Parkinson's disease. Adv Neurol 86, 83-89, 2001
664. Yasojima K, Schwab C, McGeer EG, McGeer PL. Generation of C-reactive protein and complement components in
        atherosclerotic plaques. Am J Pathol 158. 1039-1051, 2001
663. Arai Y, Ikeda K, Akiyama H, Shikamoto Y, Tsuchiya K, Yugishita S, Beach T, Rogers J, Schwab C, McGeer PL.
        Distinct isoforms of tau aggregated in neuronsand glial cells in brains of patients with Pick's disease, corticobasal
        degeneration and progressive supranuclear palsy. Acta Neuropathol 101:167-173, 2001.
662. Yasojima K, Akiyama H, McGeer EG, McGeer PL. Reduced neprilysin in high plaque areas of Alzheimer brain: a
         possible relationship to deficient degradation of b-amyloid peptide, Neurosci Lett 297:97-100 (2001)
661. McGeer PL. COX-2 and ALS. ALS and other motor disorders 2, 121-122, 2001
660. McGeer EG, McGeer PL. Chronic inflammation in Alzheimer disease offers therapeutic opportunities, Expert Rev
        Neurogenetics 1, 53-60, 2001
659. McGeer EG, McGeer PL. Innate immunity in Alzheimer's disease: a model for local inflammatory reactions. Molecular
        Interventions 1:22-29, 2001
658. McGeer PL, McGeer EG. Patrick L. McGeer and Edith Graef McGeer In: The History of Neuroscience in
        Autobiography, Squire LR (ed), Academic Press , vol 3, pp330-365, 2001
657. McGeer PL, Yasojima K, McGeer EG. Innate immunity, autotoxicity and degenerative neurologies. In: Alzheimer's
        Disease: Advances in Biology, Pathogenesis and Therapeutics. Ed Iqbal K, Sisodia SS, Winblad B, John Wiley & Sons,
        2001:331-339
656. McGeer EG, Yasojima K, McGeer PL. Inflammation in the pathogenesis of Parkinson's disease. BC Med J 43, 138-141,
        2001
655. McGeer PL, Schulzer M, McGeer EG. Antiinflammatory agents as possible protective factors for Alzheimer disease. A
        meta-analysis of relevant epidemiological studies. In: Alzheimer's Disease, Rogers J (ed) 2001 Birkhauser verlag
        Basel/Switzerland, pp 53-63
654. Walker DG, Lue L-F, Klegeris A, McGeer PL. The involvement of glial cell-derived reactive oxygen and nitrogen species 
        in Alzheimer's disease. In: Neuroinflammatory Mechanisms in Alzheimer's Disease: Basic and Clinical Research, ed Rogers
        J, 2001 Birkhauser verlag Basel/Switzerland, pp 173-195
653. McGeer PL, McGeer EG, Yasojima K. Complement, neuroinflammation and neuronal degeneration in Alzheimer disease.
        In: Neuroscientific Basis of dementia, Tanaka C, Ihara Y, McGeer PL (eds), Birkkauser Verlag AG, 2000, pp 15-20
652. Cooper N, Kalaria RN, McGeer PL, Roger J. Report of the neuroinflammationworking group. Neurobiol Aging 21:451-
        453, 2000
651. Akiyama H and 35 others including McGeer PL. Inflammation aand Alzheimer's disease. Neurobiol Aging 21:383-422.
        2000
650. Foley P, Mizuno Y, Nagatsu T, Sano A, Youdin MBH, McGeer P, McGeer E, Riederer P. The L-DOPA story - an early
        Japanese contribution. Parkinsonism & Related Dis 6:1., 2000
649. Yasojima K, Schwab C, McGeer EG, McGeer PL. Human neurons generate C-reactive protein and amyloid P:
         upregulation in Alzheimer disease. Brain Res 887:80-89, 2000
648. Lee G, Ho J, Chow S-N, Yasojima K, Schwab C, McGeer PL. Immunoidentification of gonadotropin releasing hormone
        receptor in human sperm, pituitary and cancer cells. A J Reprod Immunol 44:170-177, 2000
647. Klegeris A, McGeer PL. R(-)Deprenyl inhibits monocytic THP-1 cell neurotoxicity independent of monoamine oxidase
        inhibition. Exp Neurol 166:458-464, 2000
646. Klegeris A, Bissonnette CJ, Dorovini-Zis K, McGeer PL. Expression of complement mRNAs by human endothelial cells.
        Brain Res 871:1-6, 2000
645. Yasojima K, Kuret J, DeMaggio AJ, McGeer EG, McGeer PL. Casein kinase 2 delta mRNA is upregulated in Alzheimer
        disease brain. Brain Res 865:116-120, 2000
644. Klegeris A, McGeer EG, McGeer PL. Inhibitory action of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-
        isoquinolinecarboxamine (PK 11195) on some mononuclear phagocytic functions. Biochem Pharmacol 59:1305-1314,
        2000
643. Schwab C, McGeer PL. Ab42-carboxy terminal-like immunoreactivity is associated with intracellular neurofibrillary tangles
        and Pick bodies. Exp Neurol 161:527-534, 2000
642. Tanhehco E, Yasojima K, McGeer PL, Washington RA, Lucchesi BR. Free radicals upregulate complement expression in
         isolated rabbit heart. Am J Physiol Heart Circ Physiol 279:H195-H201, 2000
641. Schwab C, DeMaggio AJ, Ghoshal N, Binder LI, Kuret J, McGeer PL. Casein kinase 1 delta is associated with
        pathological accumulation of tau in several neurodegenerating diseases. Neurobiol Aging 21:503-510, 2000
640. Klegeris A, McGeer PL, Interaction of various intracellular signaling mechanisms involved in mononuclear phagocyte 
        toxicity towards neuronal cells. J Leukoc Biol 67:127-133, 2000
639. Tanhehco E, Yasojima K, McGeer PL, Lucchesi BR. Acute cocaine exposure upregulates complement expression in the
        rabbit heart. J Pharmacol Exp Ther 292:201-208, 2000
638. Nakagawa E, Aimi Y, Yasuhara O, Tooyama I, Shimada M, McGeer PL, Kimura H. Enhancement of progenitor cell
        division in the dentate gyrus triggered by initial limbic seizures in rat models of epilepsy. Epilepsia 41, 10-18, 2000
637. McGeer PL, McGeer EG, Yasojima K. Alzheimer disease and neuroinflammation. J Neural Transm 59[suppl]:53-57.
        2000
636. McGeer PL. Cyclooxygenase-2 inhibitors: rationale and therapeutic potential for Alzheimer's disease. Drugs & Aging
        17:1-11, 2000
635. McGeer PL, McGeer EG. Autotoxicity and Alzheimer disease. Arch Neurol 57:789-790, 2000
634. Giacobini E, McGeer PL. Approaches to the treatment of Alzheimer's disease. NeuroSci News 3:62-70, 2000
633. Doudet DJ, Holden JE, Jivan S, McGeer E, Wyatt RJ. In vivo PET studies of the dopamine D2 receptors in Rhesus 
        monkeys with long-term MPTP-induced Parkinsonism. Synapse 38:105-113, 2000
632. Van Kampen JM, McGeer EG, Stoessl AJ. Dopamine transporter function assessed in antisense knockdown in the rat: 
        protection from dopamine neurotoxicity. Synapse 37, 171-176, 2000
631. Doudet DJ, Chan GLY, Jivan S, DeJesus OT, McGeer EG, English C, Ruth TJ, Holden JE. Evaluation of dopaminergic
        presynaptic integrity: 6-[18F]fluoro-L-dopa versus 6-[18F]fluoro-L-m-tyrosine. J Cerebral Blood Flow Metab 19:278-
        287, 1999
630. Perez-Tur J, Buee L, Morris HR, Waring SC, Onstead L, Warrant-De Vrieze F, Crook R, Buee-Scherrer V, Hof PR,
        Petersen RC, McGeer PL, Delacourte A, Hutton M, Siddique T, Ahlskog JE, Hardy J, Steele JC. Neurodegenerative
        diseases of Guam: analysis of TAU. Neurology 53, 411-413, 1999
629. Schwab C, Schulzer M, Steele JC, McGeer PL. On the survival time of a tangled neuron. Neurobiol Aging 20:57-63,
        1999
628. Tanhehco E, Yasojima K, Washington RA, Kilgore KS,Homeister JW, Lucchesi BR. Preconditioning reduces tissue
         complement gene expression in the rabbit isolated heart. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): 2373-2380, 1999
627. Waterfield JD, McGeer EG, McGeer PL. The peripheral benzodiazepine receptor ligand PK 11195 inhibits arthritis in the
         MRL-lpr mouse model, Brit J Rheumatol 38:1068-1073, 1999
626. Yasojima K, McGeer EG, McGeer PL. Complement regulators C1 inhibitor and CD59 do not significantly inhibit
         complement activation in Alzheimer disease. Brain Res 833, 297-301, 1999
625. Yasojima K, McGeer EG, McGeer PL. Tangled areas of Alzheimer brain have upregulated levels of exon 10 containing
         tau mRNA. Brain Res 831, 301-305, 1999
624. Yasojima K, Schwab C, McGeer EG, McGeer PL. Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and
         proteins in human brain and peripheral organs. Brain Res 830, 226-236, 1999
623. Yasojima K, Schwab C, McGeer EG, McGeer PL. Upregulated production and activation of the complement system in 
         Alzheimer disease brain. Am J Pathol 154, 927-936, 1999
622. Klegeris A, Walker DG, McGeer PL. Toxicity of human THP-1 monocytic cells towards neuron-like cells is reduced by 
        non-steroidal antiinflammatory drugs (NSAIDs). Neuropharmacology 38, 1017-1025, 1999
621. Akiyama H, Mori H, Saido T, Kondo H, Ikeda K, McGeer PL. Occurrence of the diffuse amyloid b-protein (Ab) 
        deposits with numerous Ab-containing glial cells in the cerebral cortex of patients with Alzheimer's disease. Glia 25, 324-
        331, 1999
620. McGeer EG, McGeer PL. Brain Inflammation in Alzheimer Disease and the Therapeutic Implications, Current Pharmacol 
        Design 5:821-826, 1999
619. McGeer PL, McGeer EG. Inflammation of the brain in Alzheimer disease - implications for therapy. J Leukocyte Biol 65,
        409-415, 1999
618. McGeer EG, McGeer PL, Inflammation in Alzheimer Disease, Current Opinion in CNS Investigational Drugs 1, 340-344,
        1999
617. Steele JC, Morris HR, Lees AJ, Perez-Tur J, McGeer PL. Letter re paper by Caparros-Lefebre et al. on atypical
        parkinsonism in French West Indies. Lancet 354:1474, 1999
616. McGeer PL, McGeer EG, Parkinson's disease and the dawn of contemporary neuroscience, Neurosci News 2, 15-18,
        1999
615. Schwab C, Steele JC, Schulzer M, McGeer PL. On the Possible Lifetime of a Tangled Neuron in the Parkinson Dementia 
        Complex of Guam. In Alzheimer's Disease & Related Disorders, eds Iqbal K, Swaab DF, Winblad B, Wisniewski HM,
        John Wiley & Sons, London, 1999, pp 545-552
614. McGeer PL, Yasojima K, McGeer EG. Neuroinflammatory Mechanisms in Alzheimer Disease, In: Alzheimer's Disease &
       Related Disorders, eds Iqbal K, Swaab DF, Winblad B, Wisniewski HM, John Wiley & Sons, London, 1999, pp 429-
       437
613. McGeer PL, Schulzer M, McGeer EG.. A metaanalysis of 17 epidemiological studies indicates antiinflammatory agents
        protect against Alzheimer's disease, Medical Updates
612. McGeer EG, McGeer PL. Inflammation of the brain in Alzheimer disease: possible therapy with antiinflammatory agents.
        Progr Neurol Psychiatry 3, 25-28, 1999
611. Tourtellotte WW, Rosario IP, Riehl J, Sanders V, Syndulko K, Pick PW, McGeer PL. Banking human specimens/ In: G
        Adleman, BH Smith (eds), Encyclopedia of Neuroscience on CD ROM, pp 1-24. intenet address :www.elsevier.com/
610. McGeer EG, McGeer PL. Role of inflammatory processes and microglial activation in Alzheimer disease, In: Alzheimer's
        Disease II, R Katzman, RD Terry (eds), Lippencott, Williams & Wilkins, Philadelphia, 1999, pp 389-399
609. McGeer EG, Schwab C, McGeer PL. Apolipoprotein E and apolipoprotein J (clusterin) in the brain in Alzheimer disease,
        In: Clusterin in Normal Brain Function and During Neurodegeneration, ed C. Finch, 1999, RG Landes Co, pp 89-97
608. McGeer PL, McGeer EG. Inflammation in the brain in Alzheimer's disease: implications for therapy. Mature Med Canada
        1:37-38, 1998
607. Walker DG, McGeer EG, McGeer PL. Involvement of inflammation and complement in Alzheimer's disease. In: Clinical
        Neuroimmunology, Antel J, Birnbaum G, Hartung H-P (eds), Blackwell Science, Oxford, 1997, pp 172-188
606. McGeer EG, McGeer PL, Inflammation in the brain in Alzheimer disease: implications for therapy. NeuroSci News 1:29-
        35, 1998.
605. Walker DG, McGeer PL. Vitronectin expression in Purkinje cells in the human cerebellum. Neurosci Lett 251, 109-112,
        1998
604. Schwab C, Akiyama H, McGeer EG, McGeer PL. Extracellular neurofibrillary tangles are immunopositive for the 40
        carboxy-terminal sequence of b-amyloid protein. J Neuropath Exp Neurol 57, 1131-1137, 1998
603. Yasojima K, Schwab C, Nakagawa E, McGeer EG, McGeer PL. Human heart generates complement proteins which are
         upregulated and activated following myocardial infarction. Circulation Res 83:860-869, 1998
602. Walker DG, Kim SU, McGeer PL. Expression of complement C4 and C9 genes by human astrocytes. Brain Res 809,
         31-38, 1998
601. Takami K, Matsuo, A, Terai K, Walker, DG, McGeer EG, McGeer PL. Fibroblast growth factor receptor-1 expression
        in the cortex and hippocampus in Alzheimer's disease. Brain Res 802:89-97, 1998
600. Matsuo A, Akiguchi I, Lee GC, McGeer EG, McGeer PL, Kimura J. Myelin degeneration in multiple system atrophy
        detected by unique antibodies. Am J Pathol 153:735-744, 1998
599. Yasojima K, Kilgore K, Washington R, Lucchesi BR, McGeer PL. Complment gen expression by rabbit heart:
         upregulation by ischemia and reperfusion. Circulation Res 82:1224-1230, 1998
598. Walker DG, Beach TG, Xu R, Lile J, Beck KD, McGeer EG, McGeer PL. Expression of the proto-oncogene Ret, a
         component of the GDNF receptor complex, persists in human substantia nigra neurons in Parkinson's disease Brain Res
         792:207-217, 1998
597. Walker DG, Terai K, Matsu A, Beach TG, McGeer EG, McGeer PL. Immunohistochemical analysis of FGF receptor-l
        in the human substantia nigra: comparison between normal and Parkinson disease cases. Brain Res 794:181-187, 1998
596. McGeer EG, McGeer PL. Future use of complement inhibitors in neurodegenerative diseases. Drugs 55:739-746, 1998
595. Schwab C, Steele JC, McGeer PL. Pyramidal neuron loss is matched by increasing numbers of ghost tangles in Guam
        Parkinsonism-dementia. Acta Neuropathol96:409-416, 1998
594. McGeer PL, Kawamata T, McGeer EG. Localization and possible functions of presenilins in brain. Rev Neurosci 9:2-15,
        1998
593. Schwab C, McGeer PL. Tubulin immunopositive structures resembling intracellular neurofibrillary tangles. Neurobiol
        Aging 19:41-45, 1998
592. McGeer EG, McGeer PL. The importance of inflammatory mechanisms in Alzheimer disease. Exp Gerontology 33:371-
        378, 1998
591. McGeer EG, McGeer PL, Inflammatory mechanisms in Alzheimer's disease Neurogerontology & Neurogeriatrics 2:1-13, 
        1998
590. McGeer PL, McGeer EG, Mechanisms of cell death in Alzheimer disease - Immunopathology, J Neural Transm 53
        (suppl), 159-166, 1998
589. McGeer PL, McGeer EG, Glial cell reactions in dementia: pathophysiology and therapeutic interventions, Alz Dis Assoc
        Disorders 12 (suppl 2): S1-S6, 1998
588. Doudet DJ, Chan GLY, Holden JE, McGeer EG, Aigner TA, Wyatt RJ, Ruth TJ. 6-[18F]fluoro-L-dopa PET studies
        of the turnover of dopamine in MPTP-induced parkinsonism in monkeys. Synapse 29:225-232, 1998
587. McGeer EG. Parkinson's disease. In The Encyclopedia of Human Biology, 2nd edition, Academic Press Inc. 6:535-542,
        1997
586. McGeer EG. Huntington's disease. In The Encyclopedia of Human Biology, 2nd edition, Academic Press Inc. 4:637-643,
        1997
585. McGeer EG. Myasthenia gravis. In The Encyclopedia of Human Biology, 2nd edition, Academic Press Inc. 6:1-4, 1997
584. McGeer EG. Amyotrophic lateral sclerosis. In The Encyclopedia of Human Biology, 2nd edition, Academic Press Inc.
        1:218-236, 1997
583. Tomimoto H, Akigucji I, Matsuo A, Terai K, Watika H, Kimura J, McGeer PL, Budka H. Encephalitogenic peptide (EP) 
        in human cerebrovascular white matter lesions. Neuroreport 8;3727-3730, 1997
582. Webster S, Lue L-F, Brachova L, Tenner AJ, McGeer PL, Terai K, Walker DG, Bradt B, Cooper NR, Rogers J.
         Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease.
         Neurobiol Aging 18:415-421, 1997
581. Aimi Y, Wakabayashi Y, Yasuhara O, Matsuo A, Kwok YN, McGeer PL, Kimura H. Immunohistochemical localization
        of low affinity nerve growth factor receptor in the enteric nervous system of adult rats. Histochem J 29:529-537, 1997
580. Wszolek ZK, Vieregge P, Uitti RJ, Gasser T, Yasuhara O, McGeer PL, Berry K, Calne DB, Vingerhoets FJG, Klein C, 
        Pfeiffer RF, German-Canadian family (family A) with Parkinsonism, amyotrophy, and dementia - longitudinal observations.
        Parkinsonism & Related Disorders 3:125-139, 1997
579. Schwab C, Steele JC, McGeer PL, Dystrophic neurites are associated with early stage extracellular neurofibrillary tangles
        in the parkinsonism-dementia complex of Guam, Acta Neuropathol 94:486-492, 1997
578. Akiyama H, Mori I, Sahara N, Kondo H, Ikeda K, Nishimura T, Oda T, McGeer PL, Variable deposition of amyloid b-
         protein (Ab) with the carboxy-terminus that ends at residue valine40 (Ab40) in the cerebral cortex of patients with
         Alzheimer's disease: A double-labeling immunohistochemical study with antibodies specific for Ab40 and the Ab that ends
         at residues alanine42/threonine43 (Ab42), Neurochem Res 22:1499-1505, 1997
577. Shen Y, Li R, McGeer EG, McGeer PL, Neuronal expression of mRNAs for complement proteins of the classical 
        pathway in Alzheimer brain, Brain Res 769:391-395, 1997
576. Terai K, McGeer EG, McGeer PL, Neurons express proteins of the classical complement pathway in Alzheimer disease,
        Brain Res 769:385-390, 1997
575. Klegeris A, McGeer PL, b-amyloid protein enhances macrophage production of oxygen free radicals and glutamate, J
        Neurosci Res 49:229-235, 1997
574. Klegeris A, Walker DG, McGeer PL. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma
        U373 MG cells, J Neuroimmunol 78:152-161, 1997
573. Matsuo A, Lee GC, Terai K, Takami K, Hickey WF, McGeer EG, McGeer PL, Unmasking of an unusual myelin basic
        protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of
        autoantigens, Am J Path 150:1253-1266, 1997
572. Takami K, Terai K, Matsu A, Walker DG, McGeer PL, Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer
        disease brains, Brain Res 748:122-130, 1997
571. McGeer PL, Walker DG, Pitas RE, Mahley RW, McGeer EG. Apolipoprotein E4 (apoE4) but not apoE3 or apoE2
        potentiates beta-amyloid protein activation of complement in vitro, Brain Res 749:135-138, 1997
570. Yasuhara O, Matsuo A, Walker DG, Berger AE, Akiguchi I, Kimura J, McGeer PL, Expression of interleukin-1 receptor
        antagonist protein in postmortem human brain tissues of Alzheimer's disease, Pick's disease and control cases, Acta
        Neuropathol 93:414-420, 1997
569. McGeer PL, Schwab C, McGeer EG, Steele JC, Familial nature and continuing morbidity of the amyotrophic lateral
        sclerosis-parkinson dementia complex of Guam, Neurology 49:400-409, 1997
568. McGeer EG, McGeer PL, Aging, neurodegenerative disease and the brain, Can J Aging 16:218-236, 1997
567. Klegeris A, Walker DG, McGeer PL, Interaction of Alzheimer b-amyoid peptide with the human monocytic cell line THP-
        1 results in a protein kinase C-dependent secretion of tumor necrosis factor-a. Brain Res 747:114-121, 1997
566. Schwab C, Steele JC, McGeer EG, McGeer PL, Amyloid P immunoreactivity precedes C4d deposition on extracellular
        neurofibrillary tangles. Acta Neuropathol 93:87-91, 1997
565. McGeer EG, McGeer PL, The role of the immune system in neurodegenerative disorders, Movement Disorders 23:855-
        858, 1997
564. McGeer PL, McGeer EG, Innate inflammatory reaction in brain: possible role in the pathogenesis of Alzheimer disease
        and  therapeutic implications, Dementia Japan 11, 354-361, 1997
563. McGeer EG, McGeer PL, Innate inflammatory reaction of the brain in Alzheimer disease, McGill Medical Journal 3:134-
        141, 1997
562. Tooyama I, Uemura S, Kubota Y, Seino Y, Beach TG, Woodhurst WB, McGeer PL, Kimura H. Expression of major 
        histocompatibility complex class I and II antigens in the human hippocampus with temporal lobe epilepsy. Epilepsia 37
        (suppl 3): 64 ,1996
561. Akiyama H, Kondo H, Mori H, Kametani F, Nishimura T, Ikeda K, Kato M, McGeer P, The amino-terminally truncated
        forms of amyloid b-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients. Neurosci Lett
        219:115-118, 1996
560. Matsuo A, Walker DG, Terai K, McGeer PL, Expression of CD43 in human microglia and its downregulation in 
        Alzheimer disease, J Neuroimmunol 71:81-86, 1996
559. Terai K, Matsuo A, McGeer EG, McGeer PL, Enhancement of immunoreactivity for NF-kB in human cerebral
        infarctions, Brain Res 739:343-349, 1996
558. Tooyama I, Uemura S, Jubota Y, Seino Y, Beach TG, Woodhurst WB, McGeer PL, Kimura H, Expression of major
        histocompatability complex class I and II antigens in the human hippocampus with temoral lobe epilepsy. Epilepsia 37
        (Suppl 3): 64, 1996
557. McGeer PL, McGeer EG, Neuroimmune mechanisms in the pathogenesis of Alzheimer disease, In: Alzheimer's Disease,
        Khachaturian ZS, Radebaugh TS, eds, CRC Press, 1996, pp 218-225
556. McGeer PL, McGeer EG, CNS immune responses in Alzheimer disease, In: Immune Responses in the Nervous System,
        Rothwell NJ, ed, Bios Scientific Publishers, Oxford, U.K. , pp 143-157, 1996
555. Schwab C, Akiyama H, Steele JC, McGeer PL, Distinct distribution of apolipoprotein E and b-amyloid immunoreactivity
        in the hippocampus of Parkinson Dementia Complex of Guam, Acta Neuropathol 92:378-385, 1996
554. Terai K, Matsuo A, McGeer PL, Enhancement of immunoreactivity for NF-kB in the hippocampal formation and cerebral
        cortex of Alzheimer disease, Brain Res 735:159-168, 1996
553. Rogers J, Webster S, Lue L-F, Brachova L, Civin WH, Emmerling M, Shivers B, Walker D, McGeer P, Inflammation 
        and Alzheimer's disease pathogenesis, Neurobiol Aging 17:681-686, 1996
552. McGeer PL, Schulzer M, McGeer EG, Arthritis and antiinflammatory agents as negative risk factors for Alzheimer 
        disease: A review of seventeen epidemiological studies, Neurology 47:425-432, 1996
551. Aimi Y, McGeer PL, Lack of toxicity of human neuromelanin to rat brain dopaminergic neurons, Parkinson's Disease &
        Related Disorders 2:69-74, 1996
550. Yasuhara P, Akiguchi I, Nakamura S, Kinoshita A, Ikemoto A, Kawamoto Y, Kimura J, Funakoshi A, Takeishi K,
        McGeer PL, Pancreastatin-like immunoreactivity in globular dystrophic neurites of senile plaques in Alzheimer's disease.
         Neurosci Lett 208:167-170, 1996
549. Yasuhara O, Schwab C, Matsuo A, Kim SU, Steele JC, Akiguchi I, Kimura J, McGeer EG, McGeer PL, Midkine-like 
         immunoreactivity in extracellular neurofibrillary tangles in brains of patients with parkinsonism-dementia complex of Guam.
         Neurosci Lett 205:107-10, 1996
548. McGeer PL, McGeer EG, Antiinflammatory drugs in the fight against Alzheimer's disease. Ann NY Acad Sci 777:
        213-20,1996
547. McGeer PL, McGeer EG, Immune mechanisms in neurodegenerative disorders. Drugs of Today 32:149-158, 1996
546. Schwab C, Steele J, McGeer PL, Neurofibrillary tangles of Guam Parkinson-dementia are associated with reactive
        microglia and complement proteins, Brain Res 707:196-205, 1996
545. Rothenberger S, Food MR, Gabathuler R, Yamada T, Yasuhara O, McGeer PL, Jefferies WA, Coincident expression
        and distribution of melanotransferring and transferrin receptor in human brain capillary endothelium, Brain Res 712:117-
        121, 1996
544. Oken RJ, McGeer PL, Schizophrenia: Frequency of Alzheimer disease and possible therapeutic effect of antiinflammatory 
        agents, Schizophrenia Bull 22:1-4, 1996
543. Jefferies WA, Food MR, Gabathuler R, Rothenberger S, Yamada T, Yasuhara O, McGeer PL, Reactive microglia
        specifically associated with amyloid plaques in Alzheimer's disease brain tissue express melanotransferrin, Brain Res
        712:122-126, 1996
542. Oken RJ, McGeer PL, Schizophrenia: a 100 year retrospective. Am J Psychiatry 152:1692-3, 1995.
541. Akiyama H, Kondo H, Ikeda K, Arai T, Kato M, McGeer PL, Immunohistochemical detection of coagulation factor
        XIIIa in postmortem human brain tissue. Neurosci Lett 202:29-32, 1995
540. Uitti RJ, Berry K, Yasuhara O, Eisen A, Feldman H, McGeer PL, Calne DB, Neurodegenerative 'overlap' syndrome:
        clinical and pathological features of Parkinson's disease, motor neuron disease, and Alzheimer's disease, Parkinsonism &
        Related Disorders 1:21-34, 1995
539. McGeer PL, McGeer EG, The inflammatory response system of brain: implications for therapy of Alzheimer and other 
        neurodegenerative disorders, Brain Res Reviews 21:195-218, 1995
538. Schwab C, Steele J, Akiyama H, McGeer EG, McGeer PL, Relationship of amyloid beta/A4 protein to the neurofibrillary
        tangles in Guamanian parkinsonism-dementia, Acta Neuropathol 90:287-298, 1995
537. Tooyama I, Kawamata T, Akiyama H, Kimura H, Moestrup K, Gliemann J, Matsuo A, McGeer PL, Subcellular 
        localization of the low density lipoprotein receptor-related protein (a2-macroglobulin receptor) in human brain, Brain Res
        691:235-238, 1995
536. Oken RJ. McGeer PL, Pick's disease: new directions for prophylaxis and therapy, Ann Pharmacother 29:538, 1995
534. Oken RJ, McGeer PL, Human prion diseases: possible new directions in prophylaxis and therapy, Med Hypotheses
        44:167-168, 1995
533. Yasuhara O, Matsuo A, Tooyama I, Kimura H, McGeer EG, McGeer PL, Pick's disease immunohistochemistry: new
         alterations and Alzheimer's disease comparisons. Acta Neuropathol 89:322-330, 1995
532. Walker DG, Yasuhara O, Patston PA, McGeer EG, McGeer PL, Complement C1 inhibitor is produced by brain tissue
         and is cleaved in Alzheimer disease. Brain Res 675:75-82, 1995
531. Walker DG, Kim SU, McGeer PL, Complement and cytokine gene expression in cultured microglia derived from post-
         mortem human brain. J Neurosci Res 40:478-93, 1995
530. Oken RJ, McGeer PL, Down's syndrome: prophylaxis and therapy for the frequently comorbid Alzheimer's disease. Med
        Hypotheses 44:233-4, 1995
529. Oken RJ, McGeer PL, Letter to the editor on sterilization of dental instruments re Creutzfeld-Jakob disease, J Dental Res
        74:1836, 1995
528. McGeer PL, Can anti-inflammatories be used to treat Alzheimer's? NH Practitioner 3:19-21, 1995 (March/April)
527. McGeer PL, McGeer EG, Alzheimer's disease: arthritis of the brain? Drug News & Perspectives 8:80-3, 1995.
526. McGeer PL, McGeer EG, Chronic inflammatory mechanisms of the brain: implications for the treatment of Alzheimer
        disease, Dementia, Tokyo 9:111-123, 1995
525. McGeer PL, Tooyama I, Kimura H, McGeer EG. Basic fibroblast growth factor in the substantia nigra in Parkinson's
        disease and normal aging. In: Age Related Monoamine Dependent Disorders and their Modulation by Gene and Gender,
        Segawa M & Nomura, Y (eds), Karger, Basel, 1995, pp 235-243
524. McGeer EG, McGeer PL, Pathology of the dystonias. In: Handbook of Dystonia, Tsui JKC, Calne DB (eds), Marcel
        Dekker, Inc., New York, Basel, Hong Kong, 1995, pp77-102
523. Kawamata, T., Nakamura, S., Akiguchi, I., Tooyama, I., Seriu, N., Takemura, M., Kimura, J., Kimura, H., McGeer, E.
        G., McGeer, P. L., Higuchi, K., Hosokawa, M., and Takeda, T. (1994) Dystrophic changes in axons accumulating nitric 
        oxide synthase are accelerated with age in dorsal column nuclei of senescence accelerated mice (SAMP8). In: The SAM
        Model of Senescence. Takeda, T. (editor), Elsevier Science B. V., pp. 347-350
522. McGeer PL, McGeer EG, Growth factors in Parkinson's disease, In: Advances on Neurodegeneration, vol. II,
        Etiopathogenesis, Y Mizuno, DB Calne, R. Horowski (eds), Birkhaüser, Basel Boston Berlin, 1994, pp 19-28
521. McGeer PL, Klegeris A,Walker DG, Yasuhara O, McGeer EG, Immune mechanisms in senile plaque formation. In:
        Alzheimer Disease: Therapeutic Strategies, E. Giacobini & R Becker, eds, Birkhauser, Boston, 1994, pp 318-322
520. McGeer PL, Walker DG, Akiyama H, Yasuhara O, McGeer EG. Involvement of microglia in Alzheimer disease.
        Neuropath Appl Neurobiol 20:191-2, 1994
519. Klegeris A, McGeer PL, Comparison of respiratory burst activity between rat brain microglia and peritoneal macrophages,
        J Neuroimmunol53:83-90, 1994
518. Tooyama I, McGeer EG, Kawamata T, Kimura H, McGeer PL, Retention of bFGF immunoreactivity in dopaminergic
         neurons of the substantia nigra in humans during normal aging contrasts with loss in Parkinson's disease, Brain Res
         656:165-8, 1994
517. Yasuhara O, Walker DG, McGeer PL, Hageman factor and its binding sites are present in senile plaques of Alzheimer
        disease, Brain Res 654:234-240, 1994
516. Yasuhara O, Aimi Y, McGeer EG, McGeer PL. Expression of the complement membrane attack complex and its
        inhibitors in brains of patients with Pick disease. Brain Res 652:346-349, 1994
515. Klegeris A, McGeer PL, Inhibition of respiratory burst in macrophages by complement receptor blockade, Eur J
        Pharmacol 260:273-7, 1994
514. Yasuhara O, Aimi Y, McGeer EG, McGeer PL, Accumulation of amyloid precursor protein in brain lesions of patients
        with Pick disease, Neurosci Lett 171:63-66, 1994
513. Yasuhara O, Kawamata T, Aimi Y, McGeer EG, McGeer PL. Two types of dystrophic neurites in senile plaques of
        Alzheimer disease and elderly non-demented cases, Neurosci Lett 171:73-76, 1994
512. Yasuhara O, Kawamata T, Aimi Y, McGeer EG, McGeer PL, Expression of chromogranin A in lesions in the central
        nervous system from patients with neurological diseases, Neurosci Lett 170:13-16, 1994
511. Klegeris A, Walker DG, McGeer PL. Activation of macrophages by Alzheimer b amyloid peptide. Biochem Biophys Res
        Commun 199:984-91, 1994
510. Itagaki S, Akiyama H, Saito H, McGeer PL. Ultrastructural localization of complement membrane attack complex
        (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease. Brain Res 645:78-84, 1994
509. Yamada T, Tsubouchi H, Daikuhara Y, Prat M, Comoglio PM, McGeer PL, McGeer EG. Immunohistochemistry with
         antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues. Brain Res 637:308-12,
         1994
508. Moroo M, Yamada T., Makino T, Tooyama I, McGeer PL, McGeer EG, Loss of insulin receptor immunoreactivity from
        the substantia nigra pars compacta neurons in Parkinson's disease. Acta Neuropathol 87:343-348, 1994
507. McGeer PL, Rogers J, McGeer EG, Neuroimmune mechanisms in Alzheimer disease. Alz. Dis. & Related Disorders
        8:149-165, 1994
506. Akiyama H, Nishimura T, Kondo H, Ikeda K, Hayashi Y, McGeer PL. Expression of the receptor for macrophage
        colony stimulating factor (CSF-I) by brain microglia and its upregulation in brains of patients with Alzheimer's disease and
        amyotrophic lateral sclerosis. Brain Res 639:171-174, 1994
505. Akiyama H, Ikeda K, Katoh M, McGeer EG, McGeer PL, Expression of MRP14, 27E10, alpha-interferon and leucocyte
        common antigen by reactive microglia in postmortem human brain tissue, J Neuroimmunol 50:195-201, 1994
504. Yasuhara O, Akiyama H, McGeer EG, McGeer PL. Immunohistochemical localization of hyaluronic acid in rat and human
         brain. Brain Res 635:269-282, 1994
503. Akiyama H, Tooyama I, Kondo H, Ikeda K, McGeer EG, McGeer PL. Early response of brain resident microglia to
        kainic acid-induced hippocampal lesions. Brain Res 635:257-268, 1994
502. Yamada T, McGeer PL, Shigematsu K, McGeer EG, Calne DB, Immunohistochemical features which distinguish pallido-
        nigral-luysial atrophy from PSP, Jap J Psychiatry Neurol 48:855-63, 1994
501. McGeer PL, Klegeris A, Walker DG, Yasuhara O, McGeer EG, Pathological proteins in senile plaques, Tohoku J Exp
        Med 174:269-277, 1994
 
500. Kimura H, Tooyama I, McGeer PL, Acidic FGF expression in the surroundings of senile plaques, Tohoku J Exp Med
        174:279-293, 1994
499. Yasuhara O, Aimi Y, Yamada T, Matsuo A, McGeer EG, McGeer PL, Clusterin as a marker for ischemic Purkinje cells
        in human brain, Neurodegeneration 3:325-9, 1994
498. Hara Y, Tooyama I, Yasuhara O, Akiyama H, McGeer PL, Handa J, Kimura H, Acidic fibroblast growth factor-like
         immunoreactivity in rat brain following cerebral infarction. Brain Res 664:101-7, 1993
497. Walker DG, McGeer PL. Complement gene expression in neuroblastoma and astrocytoma cell lines of human origin.
         Neurosci Lett 157:99-102, 1993
496. Yasuhara O, Muramatsu H, Kim SU, Muramatsu T, Maruta H, McGeer PL. Midkine, a novel neurotrophic factor, is 
        present in senile plaques of Alzheimer disease. Biochem Biophys Res Commun 192:246-251, 1993
495. Akiyama H, Ikeda K, Kondoh H, Katoh M, McGeer PL. Microglia express type 2 plasminogen activator inhibitor in 
        brains of control subjects and patients with Alzheimer's disease. Neurosci Lett 164:233-235, 1993
494. Yamada T, McGeer EG, Wszolek ZK, McGeer PL, Pfeiffer RF, Rodnitzky RL. Histological and biochemical pathology
        in a family with autosomal dominant Parkinsonism and dementia. Neurol, Psychiatry and Brain Res 2:26-35, 1993
493. Akiyama H, Tooyama I, Kawamata T, Ikeda K, McGeer PL. Morphological diversities of CD44 positive astrocytes in
        the cerebral cortex of normal subjects and patients with Alzheimer disease. Brain Res 632:249-259,1993
492. Yasuhara O, Hanai K, Ohkubo I, Sasaki M, McGeer PL, Kimura H. Expression of cystatin C in rat, monkey and human 
        brains. Brain Res 628:85-92, 1993
491. Tooyama I, Kremer HPH, Hayden MR, Kimura H, McGeer EG, McGeer PL. Acidic and basic fibroblast growth factor
        in the striatum and midbrain in Huntington's disease. Brain Res 610:1-7, 1993
490. Rogers J, Kirby LC, Hempelman SR, Berry DL, McGeer PL, Kaszniak AW, Zalinski J, Cofield M, Mansukhani L, 
        Willson P, Kogan F, Clinical trial of indomethacin in Alzheimer's disease.. Neurology 43:1609-1611, 1993
489. Kawamata T, Tooyama I, Yamada T, Walker DG, McGeer PL. Lactotransferrin immunocytochemistry in Alzheimer and
        normal human brain. Am J Path 142:1574-1585, 1993
488. Akiyama H, Kawamata T, Yamada T, Tooyama I, Ishii T, McGeer PL. Expression of intercellular adhesion molecule
        (ICAM)-1 by a subset of astrocytes in Alzheimer's disease and some other degenerative neurological disorders. Acta
        Neuropath 85:628-634, 1993
487. Yamada T, Calne DB, Akiyama H, McGeer EG, McGeer PL. Further observations on Tau-positive glia in the brains with 
        progressive supranuclear palsy. Acta Neuropath 85:308-315, 1993
486. Akiyama H, Yamada T, McGeer PL, Ishii T. Columnar arrangement of amyloid deposits in Alzheimer's disease cerebral
        cortex. Acta Neuropath 85:400-403, 1993
485. Tooyama I, Kawamata T, Walker D, Yamada T, Hanai K, Kimura H, Iwane M, Igarashi K, McGeer EG, McGeer PL.
        Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson disease. Neurology 43:372-376, 1993
484. Tooyama I, Kawamata T, Akiyama H, Moestrup, SK, Gliemann J, McGeer, PL. Immunohistochemical study of a2-
        macroglobulin receptor in Alzheimer and control postmortem human brain. Mol Chem Neuropath 18:153-160, 1993
483. Mizukawa K, McGeer EG, McGeer PL, Autoradiographic study of dopamine uptake sites and its correlation with
        dopamine levels in the striata from patients with Parkinson's disease, Alzheimer's disease and neurologically normal
        controls. Mol Chem Neuropathol 18:133-144, 1993
482. McGeer PL, Kawamata T, Walker DG, Akiyama H, Tooyama I, McGeer EG, Microglia in degenerative neurological
        disease, Glia 7:84-92, 1993
481. McGeer PL, McGeer EG. Neurotransmitters and their receptors in the basal ganglia. In: Parkinson's Disease: From Basic
        Research to Treatment, Narabayashi H et al (eds). Adv Neurology 60:93-101, 1993
480. McGeer EG, McGeer PL. Neurodegeneration and the immune system. In: Neurodegenerative Diseases, Calne DB (ed),
        W.B. Saunders Co. 1993, pp 287-300
479. Pate BD, Kawamata T, Yamada T, McGeer EG, Hewitt KA, Snow BJ, Ruth TJ, Calne DB. Correlation of striatal
        fluorodopa uptake in the MPTP monkey with dopaminergic indices. Ann Neurol 34:331-8, 1993
478. Snow BJ, Tooyama I. McGeer EG, Yamada T, Calne DB, Takahashi H, Kimura H. Human positron emission
        tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels. Ann Neurol 34:324-30, 1993
477. McGeer EG, Kremer B, Hayden MR. Monoamines and their metabolites in Huntington's disease brain: evidence for
        decreased catechol-O-methyltransferase activity. Biol Psychiatry 33:551-3, 1993
476. McGeer EG, Singh EA. Angiotensin converting enzyme in cortical tissue in Alzheimer's and some other neurological
        diseases. Dementia 3:299-303, 1992
475. Beach TG, McGeer EG. Cholinergic fiber loss occurs in the absence of synaptophysin depletion in Alzheimer's disease
        primary visual cortex. Neurosci Lett 142:253-256, 1992
474. Beach TG, McGeer EG. Senile plaques, amyloid protein, and acetylcholinesterase fibers: laminar distributions in Alz
        disease striate cortex. Acta Neuropathol 83:292-90, 1992
473. McGeer PL, McGeer EG. Complement proteins and complement inhibitors in Alzheimer disease. Res Immunol 143:621-
        4, 1992
472. Parks RW, Becker RE, Dodrill KL, Bennett BA, Crockett DJ, Hurwitz TA, McGeer PL and McGeer EG. Positron
        emission tomography and neuropsychological studies in dementia. In: Alzheimer Therapy: Early Diagnosis. Taylor,
        Frances, N.Y.
471. McGeer PL, Rogers R, McGeer EG, Sibley J. Does Anti-inflammatory treatment protect against Alzheimer disease?
        In: Alzheimer's Disease: New Treatment Strategies. ZS Khachaturian, JP Blass (Eds), Marcel Dekker, N.Y. 1992, pp
        165-181
470. Rogers J, Civin WH, Styren SD, McGeer PL. Immune-related mechanisms of Alzheimer's disease pathogenesis. In:
        Alzheimer's Disease: New Treatment Strategies. ZS Khachaturian, JP Blass (Eds), Marcel Dekker, N.Y. 1992, pp
        147-163
469. McGeer PL. The pivotal role of microglia in the pathology of Alzheimer's disease. J Neuroimmunol 40:132-133, 1992
468. Peppard RF, Martin WRW, Carr GD, Grochowski E, Schulzer M, Guttman M, McGeer PL, Phillips AG, Tsui JKC,
        Calne DB. Cerebral glucose metabolism in Parkinson's disease with and without dementia. Arch Neurol 49:1262-8, 1992
467. Rogers J, Cooper NR, Webster S, Schultz J, McGeer PL, Styren SD, Civin WH, Brachova L, Bradt B, Ward P,
        Lieberburg I. Complement activation by b-amyloid in Alzheimer disease. Proc Natl Acad Sci USA 89:10016-10020,
        1992
466. McGeer EG, Singh EA, McGeer PL. Apparent anterograde transport of basic fibroblast growth factor in the rat
        nigrostriatal dopamine system. Neurosci Lett 148:31-33, 1992
465. Akiyama H, Ikeda K, Kondo H, McGeer PL. Thrombin accumulation in brains of patients with Alzheimer's disease. 
        Neurosci Lett 146:152-154, 1992
464. Tago H, Maeda T, McGeer PL, Kimura H. Butyrylcholinesterase-rich neurons in rat brain demonstrated by a sensitive
        histochemical method. J Comp Neurol 325:301-12, 1992
463. Tooyama I, Walker D, Yamada T, Hana K, Kimura H, McGeer EG, McGeer PL. High molecular weight basic fibroblast
        growth factor-like proteins are localized to a ventral subpopulation of mesencephalic dopaminergic neurons in the rat brain.
        Brain Res 595:274-280, 1992
462. Shigematsu K, McGeer PL Accumulation of amyloid precursor protein in damaged neuronal processes and microglia
        following intracerebral administration of aluminum salts. Brain Res 593:117-123, 1992
461. Shigematsu K, McGeer PL, McGeer EG. Localization of amyloid precursor protein in selective postsynaptic densities of
        rat cortical neurons. Brain Res 592:353-357, 1992
460. Yamada T. Walker DG, McGeer PL. Vimentin immunoreactivity in normal and pathological human brain tissue. Acta
        Neuropath 84:157-162, 1992
459. Wong PTH, McGeer PL, McGeer EG. Decreased prostaglandin synthesis in postmortem cerebral cortex from patients 
        with Alzheimer disease. Neurochem Intl Neurochem Intl 21:197-202, 1992
458. McGeer PL, McGeer EG. Complement proteins and complement inhibitors in Alzheimer disease. Res Immunol 143:621-
        624, 1992
457. Yamada T, McGeer PL, McGeer EG. Lewy bodies in Parkinson's disease are recognized by antibodies to complement
        proteins. Acta Neuropath 84:100-104, 1992
456. Walker DG, McGeer PL. Complement gene expression in human brains: comparison between normal and Alzheimer
        disease cases. Mol Brain Res 14:109-116, 1992
455. McGeer PL, Kawamata T, Walker DG. Distribution of clusterin in Alzheimer brain tissue. Brain Res 579:333-41, 1992
454. McGeer PL, Harada N, Kimura H, McGeer EG, Schulzer M. Prevalence of dementia amongst elderly Japanese with
        leprosy: apparent effect of chronic drug therapy. Dementia 3:146-149, 1992
453. Shigematsu K, McGeer PL. Accumulation of amyloid precursor protein in neurons following intraventricular injection of
        colchicine. Am J Pathol 140:787-794, 1992
452. Tooyama I, Yamada T, Kim SU, McGeer PL. Immunohistochemical study of A2B5-positive ganglioside in postmortem
        human brain tissue of Alzheimer disease, amyotrophic lateral sclerosis, progressive supranuclear palsy and control cases.
        Neurosci Lett 136:91-94, 1992
451. Yamada T, McGeer PL, McGeer EG. Some immunohistochemical features of argyrophilic grain dementia with normal
        cortical choline acetyltransferase levels but extensive subcortical pathology.J Geriatr Psychiatry Neurol 5:3-13, 1992
450. Shigematsu K, McGeer EG, Ishii T, McGeer PL. Reactive microglia/macrophages phagocytose amyloid precursor protein
        produced by neurons following neural damage. J Neurosci Res 31:443-453, 1992
449. McGeer PL, Akiyama H, Kawamata T, Yamada T, Walker DG, Ishii T. Immunohistochemical localization of beta-
        amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy. J Neurosci
        Res 31:428-442, 1992
448. Kawamata T, Akiyama H, Yamada T, McGeer PL. Immunological reactions in amyotrophic lateral sclerosis brain and
        spinal cord tissue. Am J Pathol 140:691-707, 1992
447. McGeer PL, Rogers J. Medical hypothesis: antinflammatory agents as a therapeutic approach to Alzheimer's disease.
        Neurology 42:447-50, 1992
446. Yamada T, McGeer PL, McGeer EG. Appearance of paired nucleated, tau positive astrocytes in brain tissue of patients
         with progressive supranuclear palsy. Neurosci Lett 135:99-102, 1992
445. Boyes BE, Walker DG, McGeer PL, McGeer EG. Identification and characterization of a large human brain gene whose
        expresssion is increased in Alzheimer disease. Mol Brain Res 12:47-57, 1992
444. Rogers J, McGeer PL. Neuroimmune mechanisms of Alzheimer disease. In: Frontiers of Alzheimer Research, pp. 243-
        249, 1991. eds T Ishii et al., Elsevier Sci Publishers
443. Itagaki S, Akiyama H, McGeer PL, McGeer EG. Characteristics of immune cells in Alzheimer disease brain. In: Frontiers
        of Alzheimer Research, pp. 231-42, 1991. Ishii T et al (eds) Elsevier, The Netherlands.
442. McGeer PL, Akiyama H, Kawamata T. Integrin expression in Alzheimer brain tissue. In: Alzheimer Disease: Basic
        Mechanisms, Diagnosis, and Therapeutic Strategies, K. Iqbal, D.R.C. McLachlan, B. Winblad, H.M. Wisniewski (Eds),
        pp 587-601, 1991, John Wiley & Sons, Ltd.
441. McGeer PL, McGeer EG, Akiyama H and Harrop R. Regional deficits in cortical metabolism in PET-scanned Alzheimer
        cases correlate with postmortem indices of gliosis, and not with choline acetyltransferase. In: Alzheimer Disease: Basic
        Mechanisms, Diagnosis, and Therapeutic Strategies, K. Iqbal, D.R.C. McLachlan, B. Winblad, H.M. Wisniewski (Eds), 
        pp 59-68, 1991, John Wiley & Sons, Ltd.
440. Parks RW, Long DL, Levine DS, Crockett DJ, McGeer EG, McGeer PL, and 7 others. Parallel distributed processing
        and neural networks: origins, methodology and cognitive functions. Intern J Neurosci 60:195-214, 1991
439. McGeer PL, McGeer EG, Kawamata T, Yamada T, Akiyama H. Reactions of the immune system in chronic degenerative 
        neurological disease. Can J Neurol Sci 18:376-379, 1991
438. Yasuhara O, Tooyama I, Akiyama H, Akiguchi I, Kimura J, McGeer, PL, Hara Y, and Kimura H. Reactive astrocytes 
        express acidic fibroblast growth factor in Alzheimer's disease brain. Dementia 2:64-70, 1991
437. Yamada T, McGeer PL and McGeer EG. Relationship of complement activated oligodendrocytes to reactive microglia
        and neuronal pathology in neurodegenerative disease. Dementia 2:71-77, 1991
436. Yamada T, Akiyama H and McGeer PL. Two types of spheroid bodies in nigral neurons in Parkinson's disease. Can J
        Neurol Sci.18:287-294, 1991
435. McGeer PL, Walker DG, Akiyama H, Kawamata T, Guan AL and Parker CJ. Detection of the membrane inhibitor of
        reactive lysis (CD59) in diseased neurons of Alzheimer brain. Brain Res. 544:315-319, l991
434. Akiyama, H, Kawamata T, Dedhar S and McGeer, PL. Immunohistochemcial localization of vitronectin, its receptor and
        beta-3 integrin in Alzheimer brain tissue. J Neuroimmunology 32:19-28, 1991
433. Tooyama I, Akiyama H, McGeer PL, Hara Y, Yasuhara O and Kimura H. Acidic fibroblast growth factor-like
        immunoreactivity in brain of Alzheimer patients. Neurosci Letts 121:155-158, 1991
432. Akiyama H, Yamada T, Kawamata T, McGeer PL. Association of amyloid P component with complement proteins in
        neurologically diseased tissue. Brain Res 548:349-352, 1991
431. O'Kusky JR, Boyes BE, Walker DG, McGeer EG. Cytomegalovirus infection of the developing brain alters catecholamine
        and indoleamine metabolism. Brain Res 559:322-30, 1991
430. McGeer EG. Amyotrophic lateral sclerosis. In The Encyclopedia of Human Biology 1:232-235, 1991, Academic Press
        Inc.
429. McGeer EG. Parkinson's disease. In The Encyclopedia of Human Biology 5:667-73, 1991, Academic Press Inc..
428. McGeer EG. Huntington's disease. In The Encyclopedia of Human Biology, 4:269-274, 1991, Academic Press Inc.
427. McGeer EG. Myasthenia gravis. In The Encyclopedia of Human Biology, 5:255-258, 1991, Academic Press Inc.
426. McGeer EG. Excitatory amino acid neurotransmission and its disorders. IN: Current Opin Neurol Neurosurg 4:548-54,
        1991
425. McGeer EG. Neurotransmitters. In: Current Opinion in Neurology and Neurosurgery Vol. 3:530-537, 1990, Current
        Science Ltd. London
424. McGeer EG, Zhu S. Lamotrigine protects against kainate but not ibotenate lesions in rat striatum. Neurosci Lett 112:348-
        351, 1990
423. Peppard RF, Martin WRW, Clark CM, Carr GD, McGeer PL and Calne DB. Cortical glucose metabolism in Parkinson's
        and Alzheimer disease. J. Neurosci Res 27:561-568, 1990.
422. Peppard RF, Martin WRW, Guttman M, Grochoswki E, Okada J, McGeer PL, Carr GD, Phillips AG, Steele JC, Tsui
        JKC, Calne DB. Cerebral glucose metabolism in Parkinson's disease and the PD complex of Guam. In: Grossman AR,
        Sambreck AM, eds, Neural Mechanisms in Disorders of Movement", John Libby, London, 1990, pp 445-452
421. Akiyama H, Itagaki S, McGeer PL, McGeer EG. Immune system reaction to model lesions of rat brain. In: Basic Clinical
        and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases (eds Nagatsu T et al.). Plenum Press, New York, 1990,
        Vol. 1, pp. 407-410
420. Itagaki S, Akiyama H, McGeer PL, McGeer EG. Characteristics of reactive microglia in Alzheimer's and Parkinson's
        disease brain tissue. In: Basic Clinical and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases (eds Nagatsu T et
        al.). Plenum Press, New York, 1990, Vol. 1, pp 381-384
419. Tago H, Numata Y, Kumashiro H, McGeer PL. Acetylcholinesterase histochemical changes in the cerebral cortex of
        Alzheimer's disease. In: Basic Clinical and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases (eds Nagatsu T 
        et al.). Plenum Press, New York, 1990, Vol. 1, pp. 391-394.
418. McGeer EG, McGeer PL, Harrop R, Akiyama H, Kamo H. Correlations of regional postmortem enzyme activities with
        premortem local glucose metabolic rates in Alzheimer's disease. J Neurosci Res 27:612-619, 1990
417. Yamada T and McGeer, PL. Oligodendroglial microtubular masses: an abnormality observed in some neurodegenerative
        diseases. Neurosci Lett 120:163-166, 1990
416. Kimura H, Tago H, Akiyama H, Hersh LB, Tooyama I and McGeer PL. Choline acetyltransferase immunopositive
        neurons in the lateral septum. Brain Res. 533:165-170, 1990.
415. Akiyama H and McGeer PL. Brain microglia constitutively express b-2 integrins. J Neuroimmunol 30:81-93, 1990
414. Yamada T, McGeer PL, Baimbridge KG, and McGeer EG. Relative sparing in Parkinson's disease of substantia nigra
        dopamine neurons containing calbindin-D28K. Brain Res. 526:303-307, 1990
413. Itagaki S, Akiyama H, McGeer PL. Immunocompetent cells identified in Alzheimer disease brain. Dementia 4:125-133, 
        1990
412. McGeer PL, Rogers J, McGeer EG and Sibley J. Does anti-inflammatory treatment protect against Alzheimer disease?
        Lancet 335:1037, 1990
411. Tooyama I, Kimura H, Akiyama H, McGeer PL. Reactive microglia express class I and class II major histocompatibility
        complex antigens in Alzheimer disease. Brain Res 523:273-280, 1990.
410. Akiyama H, Kaneko T, Mizuno N, McGeer PL. Distribution of phosphate activated glutaminase in the human cerebral
        cortex. J Comp Neurol 297:239-252, 1990
409. Yamada T, Akiyama H, McGeer PL. Complement activated oligodendroglia: A new pathogenic entity identified by
         immunostaining with antibodies to human complement proteins C3D and C4D. Neurosci Lett. 112:161-166, 1990
408. Akiyama H, Tago H, Itagaki S, McGeer PL. Occurrence of diffuse amyloid deposits in the presubicular parvopyramidal 
        layer in Alzheimer's disease. Acta Neuropathol. 79:537-544, 1990
407. Weinstein DL, Walker, DG, Akiyama H, McGeer PL. Herpes implex virus type 1 infection of the CNS induces major
         histocompatibility complex antigen expression on a rat microglia. J Neurosci Res. 26:55-65,1990
406. Boyle EA, McGeer PL. Cellular immune response in multiple sclerosis plaques. Am J Pathol 137:575-584, 1990
405. Zhu SG, McGeer EG, McGeer PL. g-Glutamyltransferase activity is unchanged in acutely quinolinate-lesioned rat
        neostriatum but is elevated in Huntington's disease caudate. Exp Neurol 107:106-109, 1990
404. Mildenberger M, Beach TG, McGeer EG, Ludgate CM. An animal model of prophylactic cranical irradiation: histologic
        effects at acute, early and delayed stages. Int J Radiat Oncol Biol Phys 18:1051-1060, 1990
403. McGeer EG, Peppard RP, McGeer PL, Tuokko H, Crockett D, Parks R, Akiyama H, Calne DB, Beattie BL, Harrop R.
        18F-Fluorodeoxyglucose positron emission tomography studies in presumed Alzheimer cases, including 13 serial scans.
        Can J Neurol Sci. 17:1-11, 1990
402. McGeer PL, Zhu SG, Dedhar S. Immunostaining of human brain capillaries by antibodies to very late antigens. J
        Neuroimmunol 26:213-218, 1990

401. McGeer EG. Excitatory amino acids and Alzheimer's disease: Idle thoughts on an exciting subject. Neurobiol Aging
        10:614-616, 1989
400. Beach TG, Walker R, McGeer EG. Lamina-selective A68 immunoreactivity in primary visual cortex of Alzheimer's disease
        patients. Brain Res 501:171-174, 1989
399. O'Kusky JR, McGeer EG. Methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake
        of choline, glutamate, and g-aminobutyric acid in the cerebral cortex and caudate-putamen. J Neurochemistry 53:999-
        1006, 1989
398. Semba K, Reiner PB, McGeer EG and Fibiger HC. Brainstem projecting neurons in the rat basal forebrain:
        Neurochemical, topographical, and physiological distinctions from cortically projecting cholinergic neurons. Brain Res Bull
        22:501-509, 1989
397. Boyes, BE., Walker, DG., McGeer, EG. and O'Kusky, JR. Increased uric acid in the developing brain and spinal cord
        following cytomegalovirus infection. J. Neurochem. J Neurochem 53:1719-1723, 1989
396. Beach TG, McGeer EG. Patterns of gliosis in Alzheimer's disease and aging cerebrum. Glia 2:420-436, 1989
395. McGeer EG. Neurotransmitters. In: Current Opinion in Neurology and Neurosurgery, Vol. 2:520-531, 1989 Current
        Science Ltd. London.
394. Walker DG, Boyes BE, McGeer PL, McGeer EG. Strategies for the identification of novel brain specific genes affected in
        Alzheimer disease. Can J Neurol Sci 16:483-489, 1989
393. Walker DG, O'Kusky JR, and McGeer PL. In situ hybridization analysis for herpes simplex virus nucleic acids in
        Alzheimer disease. Alz Dis Assoc Disorders 3:123-131, 1989
392. Parks RW, Crockett DJ, Tuokko H, Beattie BL, Ashford JW, Coburn KL, Zec RF, Becker RE, McGeer PL, McGeer
        EG. Neuropsychological "Systems efficiency" and positron emission tomography. J Neuropsychiatry 1:269-282, 1989
391. McGeer PL, Akiyama H, Itagaki S, McGeer E. Activation of the classical complement pathway in brain tissue of
        Alzheimer patients. Neurosci Lett 107:341-346, 1989
390. McGeer EG, McGeer PL, Akiyama H, Harrop R. Cortical glutaminase, b-glucuronidase and glucose utilization in
        Alzheimer's disease. Can J Neurol Sci 16:511-515, 1989
389. Itagaki S, McGeer PL, Akiyama H, Beattie BL, Walker DG, Moore GRW, McGeer EG. A case of adult onset dementia
        with argyrophilic grains. Ann Neurol 26:685-689, 1989
388. McGeer PL, McGeer EG, Akiyama H, Itagaki S, Harrop R and Peppard R. Neuronal degeneration and memory loss in
        Alzheimer's disease and aging. In: The Principles of Design and Operation of the Brain, pp 411-426, 1990, Eds. J.C.
        Eccles and O Creutzfeldt, Pontificiae Academiae Scientiarvm Scripta Varia 78
387. McGeer PL, Itagaki S, Tago H, McGeer EG. Occurrence of HLA-DR reactive microglia in Alzheimer's disease. 
        Advances in Immunol., ed Raines, Ann NY Acad Sci 540:319-323, 1989
386. McGeer EG, McGeer PL. Biochemical neuroanatomy of the basal ganglia. In: Drugs for the Treatment of Parkinson's
        Disease. DB Calne (ed), Springer-Verlag, Berlin, pp 113-148, 1989
385. McGeer PL, McGeer EG. Amino acid neurotransmitters. In: Basic Neurochemistry, 4th ed. G Siegel, RW Albers, BW
        Agranoff, P Molinoff (eds), Raven Press, NY, pp 311-332. 1989
384. Itagaki S, McGeer PL, Akiyama H, Zhu S, Selkoe D. Relationship of microglia and astrocytes to amyloid deposits of
        Alzheimer disease. J Neuroimmunol. 24:173-182, 1989
383. McGeer PL, Akiyama H, Itagaki S, McGeer EG. Immune system response in Alzheimer's disease. Can J Neurol Sci
        16:516-527, 1989
382. Zhu SG, McGeer EG, McGeer PL. Effect of MK-801, kynurenate, glycine, dextrorphan and 4-acetylpyridine on striatal
        toxicity of quinolinate. Brain Res 481:356-360, 1989
381. Tago H, McGeer PL, McGeer EG, Akiyama H, Hersh LB. Distribution of choline acetyltransferase immunopositive 
        structures in the rat brain stem. Brain Res 495:271-297, 1989
380. Parks RW, Crockett DJ, McGeer PL. Systems model of cortical organization: PET and neuropsychological test
        performance. Arch Clin Neuropsychol 4:335-349, 1989
379. McGeer EG, McGeer PL. Effect of fixatives on rat brain acetylcholinesterase activity. J Neurosci Methods 28:235-237,
        1989
378. Mizukawa K, Vincent S, McGeer PL, McGeer EG. Distribution of reduced nicotinamide adenine dinucleotide phosphate
        (NADPH) diaphorase positive cells and fibers in the cat central nervous system. J Comp Neurol 279:281-311, 1989
377. Akiyama H, McGeer PL, Itagaki S, McGeer EG, Kaneko T. Loss of glutaminase-positive cortical neurons in Alzheimer's
        disease. Neurochem Res 14:353-359, 1989
376. Akiyama H, Harrop R, McGeer PL, Peppard R, McGeer EG. Crossed cerebellar and uncrossed basal ganglia diaschisis
        in Alzheimer's disease. Neurology 39:541-548, 1989
375. Walker DG, Itagaki S, Berry K, McGeer PL. Examination of brains of AIDS cases for human immunodeficiency virus
        and human cytomegalovirus nucleic acid. J Neurol Neurosurg Psychiat 52:583-590, 1989
374. Akiyama H, McGeer PL. Microglial response to 6-hydroxydopamine-induced substantia nigra lesions. Brain Res
        489:247-253, 1989
373. Calne DB, McGeer PL. Tissue transplantation for Parkinson's disease. Can J Neurol Sci 15:364-365, 1988.
372. Kamo H, McGeer, PL. Analysis of cortical glucose metabolism with PET in dementia - Alzheimer type dementia and
        Pick's disease. Adv Med 145:727-31, 1988
371. Mizukawa K, Vincent SR, McGeer PL, McGeer EG. Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-
        diaphorase-positive neurons in cat cerebral white matter. Brain Res 461:274-81, 1988
370. McGeer EG, McGeer PL. The dystonias. Can J Neurol Sci 15:447-483, 1988
369. Zhu SG, McGeer EG, Singh EA, McGeer PL. Tetrahydroaminoacridine (THA) potentiates neurotoxicity of quinolinic
        acid in rat striatum. Neurosci Lett 95:252-256, 1988
368. McGeer PL, Itagaki S, Akiyama H, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological
        process. Ann Neurol 24:574-6, 1988
367. McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of
        Parkinson's and Alzheimer's disease brains. Neurology 38:1285-91, 1988
366. McGeer PL, Itagaki S, McGeer EG. Expression of the histocompatibility glycoprotein HLA-DR in neurological disease.
        Acta Neuropathol (Berl) 76:550-557, 1988
365. McGeer EG, Singh EA, McGeer PL. Peripheral-type benzodiazepine binding in Alzheimer's disease. Alz Dis Assoc
        Disorders 2:331-6, 1988
364. Mizukawa K, McGeer PL, Vincent SR, McGeer EG. Ultrastructure of reduced nicotinamide adenine dinucleotide
        phosphate (NADPH) diaphorase positive neurons in the cat cerebral cortex, amygdala and caudate nucleus. Brain Res
        452:286-92, 1988
363. Mizukawa K, Otsuka N, McGeer PL, Vincent SR, McGeer EG. The ultrastructure of somatostatin-immunoreactive cell
        bodies, nerve fibers and terminals in the dorsal horn of rat spinal cord. Arch Histol Cytol 51:443-452, 1988
362. Itagaki S, McGeer PL, Akiyama H. Presence of T-cytotoxic-suppressor and leucocyte common antigen positive cells in
        Alzheimer's disease brain tissue. Neurosci Lett 91:259-64, 1988
361. Akiyama H, Itagaki S, McGeer PL. Major histocompatibility complex antigen expression on rat microglia following
        epidural kainic acid lesions. J Neurosci Res 20:147-57, 1988
360. Boyes BE, Walker DG, McGeer PL. Separation of large DNA restriction fragments on a size-exclusion column by a
        nonideal mechanism. Anal Biochem 170:127-34, 1988
359. Araki M, McGeer PL, Kimura H. The afferent projections of the rat lateral habenular nucleus revealed by the PHA-L
        anterograde tracing method. Brain Res 441:319-30, 1988
358. McGeer EG, McGeer PL. Central cholinergic pathways: histochemical evidence. In: Handbook of Experimental
        Pharmacology, Vol 86: The Cholinergic Synapse. VP Whittaker (ed), Springer-Verlag, Berlin, Heidelberg, pp 615-627,
        1988
357. McGeer EG, McGeer PL. Excitotoxins and animal "models" of human disease. In: NATO ASI Series (A), Vol 100:
        Recent Advances in Nervous System Toxicology. CL Galli, L Manzo, PS Spencer (eds), Plenum Press, pp 107-131,
        1988
356. McGeer PL, Itagaki S, Akiyama H, McGeer EG. Immune system response in Alzheimer's disease. In: The Molecular
        Biology of Alzheimer's Disease. CE Finch, P Davies (eds), Cold Spring Harbor Laboratory, 1988, pp 47-50
355. McGeer EG. The use of neurotransmitter indices and the deoxyglucose technique to study neurotoxic effects. In: NATO
        ASI Series (A): Life Sciences, Vol 100: Recent Advances in Nervous System Toxicology (Eds CL Galli, L Manzo, PS
        Spencer), Plenum Press, NY, pp 351-63, 1988
354. Reiner PB, McGeer EG. THA increases action potential duration of central histamine neurons in vitro. Eur J Pharmacol
        155:265-70, 1988
353. Beach TG, McGeer EG. Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual
        cortex. Brain Res 463:357-361, 1988
352. Semba K, Reiner PB, McGeer EG, Fibiger HC. Non-cholinergic basal forebrain neurons project to the contralateral basal
        forebrain in the rat. Neurosci Lett 84:23-28, 1988
351. O'Kusky JR, Boyes BE, McGeer EG. Methylmercury-induced movement and postural disorders in developing rat:
        regional analysis of brain catecholamines and indoleamines. Brain Res 439:138-146, 1988
350. Cumming P, Hausser M, Martin WRW, Grierson J, Adam MJ, Ruth TJ, McGeer EG. Kinetics of in vitro decarboxylation
        and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat. Biochem Pharmacol 37:247-50, 1988
349. Semba K, Reiner PB, McGeer EG, Fibiger HC. Brainstem afferents to the magnocellular basal forebrain studied by axonal
        transport, immunohistochemistry, and electrophysiology in the rat. J Comp Neurol 267:433-53, 1988
348. Reiner PB, Semba K, Fibiger HC, McGeer EG. Ontogeny of histidine decarboxylase-immunoreactive neurons in the
         tuberomammillary nucleus of the rat hypothalamus: timne of origin and development of transmitter phenotype. J Comp
         Neurol 276:304-311, 1988
347. Beach TG, McGeer EG. Retrograde filling of pyramidal neurons in postmortem human cerebral cortex using horseradish 
        peroxidase. J Neurosci Methods 23:187-193, 1988
346. Cumming P, Boyes BE, Martin WRW, Adam M, Ruth TJ, McGeer EG. Altered metabolism of 18F-6-fluorodopa in the
        hooded rat following inhibition of catechol-O-methyltransferase with U-0521. Biochem Pharm 36:2527-2531, 1987
345. McGeer EG. Commentary in Alz Dis and Assoc Disorders. An Int'l Journal:152-55, 1987
344. Beach TG, McGeer EG. Further methodological problems in cell counting. Neurobiol Aging 8:570-571, 1987
343. Reiner PB, McGeer EG. Electrophysiological properties of cortically projecting histamine neurons of the rat hypothalamus.
        Neurosci Lett 73:43-47, 1987
342. Semba K, Reiner PB, McGeer EG, Fibiger HC. Morphology of cortically projecting basal forebrain neurons in the rat as
        revealed by intracellular inotophoresis of horseradish peroxidase. Neuroscience 20:637-51, 1987
341. Reiner PB, Semba K, Fibiger HC, McGeer EG. Physiological evidence for subpopulations of cortically projecting basal
        forebrain neurons in the anesthetized rat. Neuroscience 20:629-36, 1987
340. Beach TG, Tago H, McGeer EG. Light microscopic evidence for a substance P-containing innervation of the human
        nucleus basalis of Meynert. Brain Res 408:2521-57, 1987
339. Beach TG, McGeer EG. Tract-tracing with horseradish peroxidase in the post-mortem human brain. Neurosci Lett 76:37-
        41, 1987
338. Cumming P, Boyes BE, Martin WRW, Adam M, Grierson J, Ruth T, McGeer EG. The metabolism of 18F-6-fluoro-L-
        3,4-dihydroxyphenylalanine in the hooded rat. J Neurochem 48:601-8, 1987
337. Tago H, Reiner PB, McGeer EG. Coupled intracellular horseradish peroxidase-monoamine oxidase histochemistry: 
        description of the technique and its application to the study of physiologically identified tuberomammillary neurons. J
        Neurosci Methods 20:271-81, 1987
336. Cumming P, Kamo H, McGeer EG, McGeer PL. Toxicity of p-methoxyphenol to dopamine neurons in the rat substantia
        nigra. Neuropharmacology 26:1795-97, 1987
335. Okoyama S, Tago H, McGeer PL, Hersh LB, Kimura H. Cholinergic divergent projections from rat basal forebrain to the
        hippocampus and olfactory bulb. Neurosci Lett 83:77-81, 1987
334. Mizukawa K, McGeer PL, Vincent SR, McGeer EG. The distribution of somatostatin-immunoreactive neurons and fibers 
        in the rat cerebral cortex: light and electron microscope studies. Brain Res 426:28-36, 1987
333. Tomimoto H, Kamo H, Kameyama M, McGeer PL, Kimura H. Descending projections of the basal forebrain in the rat
        demonstrated by the anterograde neural tracer phaseolus vulgaris leucoagglutinin (PHA-L). Brain Res 425:248-55, 1987
332. McGeer EG, Singh EA, McGeer PL. Sodium-dependent glutamate binding in senile dementia. Neurobiol Aging 8:219-23,
        1987
331. McGeer PL, Itagaki S, Tago H, McGeer EG. Reactive microglia in patients with senile dementia of the Alzheimer type are 
        positive for the histocompatibility glycoprotein HLA-DR. Neurosci Lett 79:195-200, 1987
330. McGeer PL, McGeer EG, Itagaki S, Mizukawa K. Anatomy and pathology of the basal ganglia. Can J Neurol Sci
        14:363-72, 1987
329. Kamo H, Kim SU, McGeer PL, Araki M, Tomimoto H, Kimura H. Transplantation of cultured human spinal cord cells
        into the rat motor cortex: use of phaseolus vulgaris leucoagglutinin as a cell marker. Neurosci Lett 76:163-7, 1987
328. Kamo H, Kim SU, McGeer PL, Tago H, Shin DH. Transplantation of cultured human adrenal chromaffin cells into 6-
        hydroxydopamine lesioned rat brain. Synapse 1:324-28, 1987
327. Kamo H, Haebara H, Akiguchi I, Kameyama M, Kimura H, McGeer PL. A distinctive distribution of reactive astroglia in
        the precentral cortex in amyotrophic lateral sclerosis. Acta Neuropathol (Berl) 74:33-38, 1987
326. Kamo H, McGeer PL, Harrop R, McGeer EG, Calne DB, Martin WRW, Pate BD. Positron emission tomography and
        histopathology in Pick's disease. Neurology 37:439-45, 1987
325. Tago H, McGeer PL, McGeer EG. Acetylcholinesterase fibers and the development of senile plaques. Brain Res 406:366-
        9, 1987
324. Tago H, McGeer PL, Bruce G, Hersh LB. Distribution of choline acetyltransferase-containing neurons of the 
        hypothalamus. Brain Res 415:49-62, 1987
323. Beach TG, Tago H, Nagai T, Kimura H, McGeer PL, McGeer EG. Perfusion fixation of the human brain for
        mmunohistochemistry: comparison with immersion fixation. J Neurosci Meth 19:183-92, 1987
322. McGeer EG, Singh EA, McGeer PL. g-Glutamyltransferase: normal cortical levels in Alzheimer's disease. J Alz Dis Assoc
        Disorders 1:38-42, 1987
321. McGeer PL, Itagaki S, Akiyama H, McGeer EG. Comparison of neuronal loss in Parkinson's disease and aging. In: Aging
        Series, Vol 36, Parkinsonism and Aging, Raven Press, NY.
320. McGeer PL, McGeer EG, Mizukawa K, Tago H, Peng JH. Distribution of cholinergic neurons in human brain. In:
        Neurobiology of Acetylcholine. NJ Dun, RL Perlman (eds), Plenum Press, pp 3-26, 1987
319. McGeer PL, McGeer EG. Integration of motor functions in the basal ganglia. In: Advances in Behavioral Biology, Vol 32,
        The Basal Ganglia II, Structure & Function - Current Concepts. MB Carpenter, A Jayaraman (eds), Plenum Press, NY,
        pp 429-42, 1987
318. McGeer PL, Itagaki S, McGeer EG, Mizukawa K. Immunohistochemistry of Parkinson's disease and other basal ganglia 
        disorders. In: Recent Developments in Parkinson's Disease. S Fahn, CD Marsden, D Calne, M Goldstein (eds),
        Macmillan Healthcare Information, New Jersey, pp 31-45, 1987
317. McGeer EG, McGeer PL. Biochemical neuroanatomy and Alzheimer's disease. In: Advancing Frontiers in Alzheimer's
        Disease Research. GG Glenner, RJ Wurtman (eds), U Texas Press, Austin, Texas, pp 53-69, 1987
316. McGeer PL, McGeer EG, Peng JH. The cholinergic system of the brain. In: Neurohistochemistry: Modern Methods and 
        Applications. Eds P Panula, H Paivarinta, S Soinila, Alan R Liss Inc, pp 355-73, 1986
315. McGeer PL, McGeer EG, Kimura H, Peng J-F. Cholinergic neurons and cholinergic projections in the mammalian CNS.
        In: Advances in Behavioral Biology, Vol 36, Dynamics of Cholinergic Function. Ed EI Hanin. Plenum Press, NY &
        London, pp 11-21, 1986
314. McGeer PL, Kamo H, Harrop R, McGeer EG, Martin WRW, Pate BD, Li DKB. Comparison of PET, MRI and CT
        with pathology in a proven case of Alzheimer's disease. Neurology 36:1569-74, 1986
313. Kamo H, Kim SU, McGeer PL, Shin DH. Functional recovery in a rat model of Parkinson's disease following
        transplantation of cultured human sympathetic neurons. Brain Res 397:373-6, 1986
312. McGeer PL, McGeer EG, Kamo H, Wong K. Positron emission tomography and the possible origins of cytopathology in
        Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiat 10:501-18, 1986
311. Mizukawa K, McGeer PL, Tago H, Peng JH, McGeer EG, Kimura H. The cholinergic system of the human hindbrain
        studied by choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Brain Res 379:39-55,
        1986
310. McGeer EG, McGeer PL, Kamo H, Tago H, Harrop R. Cortical metabolism, acetylcholinesterase staining and
        pathological changes in Alzheimer's disease. Prog Neuro-Psychopharmacol Biol Psychiat 10:501-18, 1986.
309. McGeer EG, McGeer PL. Possible destruction of cholinoceptive neurons by overstimulation of cholinergic tracts. Can J
        Physiol Pharmacol 64:363-8, 1986
308. Peng JH, McGeer PL, McGeer EG. Membrane-bound choline acetyltransferase from human brain: purification and
        properties. Neurochem Res 11:959-71, 1986
307. McGeer PL, Kamo H, Harrop R, et al. Positron emission and magnetic resonance imaging of clinically diagnosed
        Alzheimer's disease patients. Can Med Assoc J 134:597-607, 1986
306. McGeer PL. Brain imaging in Alzheimer's disease. Br Med Bull 42:24-28, 1986
305. Boyes BE, Cumming P, Martin WRW, McGeer EG. Determination of plasma [18F]-6-fluorodopa during positron
        emission tomography: elimination and metabolism in carbidopa treated subjects. Life Sci 39:2243-52, 1986
304. Calne DB, Eisen A, McGeer EG, Spencer S. Alzheimer's disease, Parkinson's disease, and motoneurons disease:
        abiotropic interaction between aging and environment. The Lancet 1067-70, 1986
303. Cumming P, von Krosigk M, Reiner PB, McGeer EG, Vincent SR. Absence of adrenaline neurons in the guinea pig brain:
        a combined immunohistochemical and high performance liquid chromatography study. Neurosci Lett 63:125-30, 1986
302. O'Kusky JR, McGeer EG. Methylmercury poisoning of the developing nervous system in the rat: decreased activity of
        glutamic acid decarboxylase in cerebral cortex and neostriatum. Dev Brain Res 21:299-306, 1985
301. Thompson SG, McGeer EG. GABA-transaminase and glutamic acid decarboxylase changes in the brains of rats treated
         with pyrithiamine. Neurochem Res 10:1653-60, 1985

300. Thompson SG, Wong PT-H, Leong SF, McGeer EG. Regional distribution in rat brain of 1-pyrroline dehydrogenase and
        its localization to specific glial cells. J Neurochem 45:1791-96, 1985
299. McGeer EG, Normal M, Boyes B, O'Kusky J, Susuki J, McGeer PL. Acetylcholine and aromatic amine systems in
        postmortem brain of an infant with Down's syndrome. Exp Neurol 87:555-70, 1985
298. Turnbull IM, McGeer PL, Beattie L, Calne D, Pate B. Stimulation of the basal nucleus of Meynert in senile dementia of
        Alzheimer's type (a preliminary report). Appl Neurophysiol 48:216-21, 1985
297. Kamo H, Kim SU, McGeer PL, Shin DH. Transplantation of cultured fetal human adrenal chromaffin cells to rat brain.
        Neurosci Lett 57:43-48, 1985
296. Araki M, McGeer PL, McGeer EG. Striatonigral and pallidonigral pathways studied by a combination of retrograde
        horseradish peroxidase tracing and a pharmacohistochemical method for g-aminobutyric acid transaminase. Brain Res
        331:17-24, 1985
295. Araki M, McGeer PL, McGeer EG. Differential effect of kainic acid on somatostatin, gabaergic and cholinergic neurons in
        the rat striatum. Neurosci Lett 53:197-202, 1985
294. Nagai T, Maeda T, Imai H, McGeer PL, McGeer EG. Distribution of GABA-T-intensive neurons in the rat hindbrain. J
        Comp Neurol 231:260-9, 1985
293. McGeer EG, McGeer PL. Neurotoxin-induced animal models of human disease. In: Neurotoxicology. Eds L Manzo, K
        Blum, Marcel Dekker Inc, NY pp 515-33, 1985
292. McGeer PL. In: If I were Prime Minister. Hurtig Publishers, Edmonton, pp181-185,1984
291. McGeer PL, Kimura H, McGeer EG. Transplantation of newborn brain tissue into adult kainic acid lesioned neostriatum.
        In: Neural Transplants: Development and Function. Eds JR Sladek Jr, DM Gash, Plenum Publishing Corp, NY, pp 361-
        71, 1984
290. Nagai T, McGeer PL, Araki M, McGeer EG. GABA-T-intensive neurons in the rat brain. In: Handbook of Chemical
        Neuroanatomy, Vol 3, Classical Transmitters and Transmitter Receptors in the CNS, Part II. Eds J Bjorklund, T Hokfelt,
        MJ Kuhar, Elsevier Science Publishing Co, Inc, NY pp 247-69, 1984
289. Kimura H, McGeer PL, Peng J-H. Choline acetyltransferase-containing neurons in the rat brain. In: Handbook of
        Chemical Neuroanatomy, Vol 3, Classical Transmitters and Transmitter Receptors in the CNS, Part II. Eds J Bjorklund,
        T Hokfelt, MJ Kuhar, Elsevier Science Publishing Co, Inc, NY pp 51-65, 1984
288. McGeer PL, McGeer EG. Cholinergic systems and cholinergic pathology. In: Handbook of Neurochemistry, 2nd ed, Vol
        6. Receptors in the Nervous System. Ed A Lajtha, Plenum Press, pp 379-410, 1984
287. Araki M, McGeer PL, McGeer EG. Presumptive g-aminobutyric acid pathways from the midbrain to the superior
        colliculus studied by a combined horseradish peroxidase-g-aminobutyric acid transaminase pharmacohistochemical
        method. Neuroscience 13:433-49, 1984
286. McGeer PL. Aging, Alzheimer's disease, and the cholinergic system. Can J Physiol Pharmacol 62:741-54, 1984
285. McGeer PL, McGeer EG, Peng JH. Choline acetyltransferase: purification and immunohistochemical localization. Life Sci
        34:2319-38, 1984.
284. McGeer EG, McGeer PL. Substantia nigra cell death from excitotoxins in the pontine tegmentum. Brain Res 298:339-42,
        1984
283. McGeer EG, Staines WA, McGeer PL. Neurotransmitters in the basal ganglia. Can J Neurol Sci 11:89-98, 1983
282. Araki M, McGeer PL, McGeer EG. Retrograde HRP tracing combined with a pharmacohistochemical method for GABA
        transaminase for the identification of presumptive GABAergic projections to the habenula. Brain Res 304:271-7, 1984
281. Peng JH, McGeer PL, McGeer EG. Anti-human choline acetyltransferase fragments antigen binding (FAB)-sepharose
        chromatography for enzyme purification. Neurochem Res 8:1481-86, 1983
280. McGeer PL, McGeer EG, Suzuki J, Dolman, CE, Nagai T. Aging, Alzheimer's disease and the cholinergic system of the
        basal forebrain. Neurology 34:741-5, 1984
279. Calne DB, Duvoisin RC, McGeer EG. Speculations on the etiology of Parkinson's disease. In: Advances in Neurology,
        Vol 40 (Eds RG Hassler & JF Christ), Raven Press, NY, pp 353-60, 1984
278. Wong PT-H, Singh VK, McGeer EG. Sodium-independent glutamic acid binding in cultured fibroblasts from patients with
        Huntington's disease. Neurochem Int 6;245-47, 1984
277. McGeer EG, Singh EA. Neurotoxic effects of endogenous materials: quinolinic acid -pyroglutamic acid and thyroid
        releasing hormone (TRH). Exp Neurol 86:410-13, 1984
276. Beach TG, McGeer EG. The distribution of substance P in the primate basal ganglia: an immunohistochemical study of
        baboon and human brain. Neuroscience 13:29-52, 1984
275. Beach TG, McGeer EG. Neocortical substance P neurons in the baboon: an immunohistochemical finding. Neurosci Lett
        41:265-70, 1983
274. Scherer-Singler U, Vincent SR, Kimura H, McGeer EG. Demonstration of a unique population of neurons with NADPH-
        diaphorase histochemistry. J Neurosci Methods 9:229-34, 1983
273. Nagai T, Pearson T, Peng F, McGeer EG, McGeer PL. Immunohistochemical staining of the human forebrain with
        monoclonal antibody to human choline acetyltransferase. Brain Res 265:300-6, 1983
272. Nagai T, McGeer PL, Peng JH, McGeer EG, Dolman CE. Choline acetyltransferase immunohistochemistry in brains of
        Alzheimer's disease patients and controls. Neurosci Lett 36:195-9, 1983
271. Nagai T, McGeer PL, McGeer EG. Distribution of GABA-T intensive neurons in the rat forebrain and midbrain. J Comp
        Neurol 218:220-38, 1983
270. Noda Y, McGeer PL, McGeer EG. Lipid peroxide distribution in brain and the effect of hyperbaric oxygen. J Neurochem
        40:1329-32, 1983
269. Wong PT-H, McGeer EG, Singh K, McGeer PL. Changes in muscarinic binding in distant brain regions showing neuronal
        losses after folic acid injections into the substantia innominata. J Neurochem 40:1754-57, 1983
268. McGeer PL, McGeer EG, Nagai T. GABAergic and cholinergic indices in various regions of rat brain after intracerebral
        injections of folic acid. Brain Res 260:107-16, 1983
267. Kamei I, Nagai T, McGeer PL, McGeer EG. Evidence for an intracellular acetylcholinesterase-rich but probably non-
        cholinergic flocculo-nodular projection in the rat. Brain Res 258:115-9, 1983
266. McGeer EG, McGeer PL, Thompson S. GABA and glutamate enzymes. In: Glutamine, Glutamate, and GABA in the
        Central Nervous System. Eds L Hertz, E Kvamme, EG McGeer, A Schousboe. Alan R Liss Inc, NY, pp 3-18, 1983
265. McGeer PL, McGeer EG, Nagai T, Wong P-T. A possible relationship between folic acid neurotoxicity and cholinergic
        receptors in the pyriform cortex and amygdala. In: J Neural Trans Suppl 18: Basic Aspects of Receptor Biochemistry
        (Proc Int'l Symp, Vienna, Sept 1982). Eds M Goldstein, K Jellinger, P Riederer, Springer-Verlag, Wien, NY, pp
         327-44, 1983
264. Kimura H, McGeer EG, Peng F, McGeer PL. Cholinergic systems in the cat cortex studied by choline acetyltransferase
        immunohistochemistry. In: Structure and Function of Peptidergic and Aminergic Neurons (Taniguchi Symposia on Brain
        Sciences No. 5; eds Y Sano, Y Ibata, EA Zimmerman), Japan Soientific Societies Press, Tokyo, 1983, pp. 263-274
263. McGeer PL, McGeer EG. Excitotoxic amino acids as tools in neurobiology. Reviews in Pure and Applied Pharmacological
        Sciences. Ed M Segal, 4:213-70, 1983
262. McGeer PL, Durbin E, The urgency for a multi-national alternative fuels program. In: Methane - Fuel for the Future, Eds.
        PL McGeer, E. Durbin, Plenum Press, New York, pp 1-18, 1982
261. McGeer EG, McGeer PL. Neurotransmitters in normal aging. In: Geriatrics 1. Ed D Platt, Springer-Verlag, Berlin,
        Heidelberg, pp 263-82, 1982
260. McGeer EG, McGeer PL, Vincent SR. GABA enzymes and pathways in the CNS. In: Neurotransmitter Interaction and
        Compartmentation. Ed HF Bradford, Plenum Press, NY, pp 299-327, 1982
259. McGeer PL, Kimura H, McGeer EG, Peng JH. Cholinergic systems in the CNS. In: Neurotransmitter Interaction and
        Compartmentation. Ed HF Bradford, Plenum Press, NY, pp 255-89, 1982
258. McGeer PL, McGeer EG. Kainic acid: the neurotoxic breakthrough. In: CRC Critical Reviews in Toxicology, Vol 10. Ed 
        L Goldberg, CRC Press Inc, Fla, USA, pp 1-26, 1982
257. Wong PT-H, McGeer EG, McGeer PL. Effects of kainic acid injection and cortical lesion on ornithine and aspartate
        aminotransferases in rat striatum. J Neurol Res 8:643-50, 1982
256. Noda Y, McGeer PL, McGeer EG. Lipid peroxides in brain during aging and vitamin E deficiency: possible relations to
        changes in neurotransmitter indices. Neurobiol Aging 3:173-8, 1982
255. Peng JH, McGeer PL, McGeer EG. Cross-reactivity of antibodies to chicken brain choline acetyltransferase with
        mammalian enzyme. J Neuroimmunol 3:113-21, 1982
254. Nagai T, Kimura H, Maeda T, McGeer PL, Peng F, McGeer EG. Cholinergic projections from the basal forebrain of rat 
        to the amygdala. J Neurosci 2:513-20, 1982
253. Brownell GL, Budinger, TF, Lauterbur PC, McGeer PL. Positron tomography nuclear magnetic resonance imaging.
        Science 215:619-26, 1982
252. Wong PT-H, McGeer PL, Rossor M, McGeer EG. Ornithine aminotransferase in Huntington's disease. Brain Res
        231:466-71, 1982
251. Vincent SR, Kimura H, McGeer EG. A histochemical study of GABA-transaminase in the efferents of the pallidum. Brain
         Res 241:162-165, 1982
250. Vincent SR, Kimura H, McGeer EG. GABA-transaminase in the basal ganglia: a pharmacohistochemical study. Brain Res
         251:93-104, 1982
249. Noda Y, Wada JA, McGeer EG. Lasting influence of amydaloid kindling on cholinergic neurotransmission. Exp Neurol 
        78:91-98, 1982
248. Vincent SR, Kimura H, McGeer EG. The histochemical localization of GABA-transaminase in the efferents of the striatum.
        Brain Res 222:198-203, 1981
247. Vincent SR, Kimura H, McGeer EG. Organization of substance P fibers within hippocampal formation demonstrated with
        biotin-avidin immunoperoxidase technique. J Comp Neurol 199:133-23, 1981
246. McCaughran JA, McGeer EG. Iontophoresis of kainic acid. Neurochem Res 1:97-98, 1981
245. Vincent SR, McGeer EG. A substance P projection to the hippocampus. Brain Res 215:349-351, 1981
244. Wong PT-H, McGeer EG. Postnatal changes of gabaergic and glutamatergic parameters. Develop Brain Res 1:519-29,
        1981
243. McGeer EG. Neurotransmitter systems in aging and senile dementia. Prog Neuro-Psychopharmacol 5:435-45, 1981
242. Kimura H, McGeer PL, Peng JH, McGeer EG. The central cholinergic system studied by choline acetyltransferase
        mmunohistochemistry in the cat. J Comp Neurol 200:152-201, 1981
241. Noda Y, Kimura H, McGeer PL. Glycosis in rat neostriatal slices following kainic acid injections. Brain Res 214:451-454,
        1981
240. Wong PT-H, McGeer EG, McGeer PL. A sensitive radiometric assay for ornithine aminotransferase: regional and 
        subcellular distributions in rat brain. J Neurochem 36:501-505, 1981
239. Peng JH, Kimura H, McGeer PL, McGeer EG. Anti-choline acetyltransferase fragments antigen binding (FAB) for
        immunohistochemistry. Neurosci Lett 21:281-5, 1981
238. Kimura H, McGeer PL, Peng JH, McGeer EG. Mapping of cholinergic systems in rostral forebrain of the rodent. In: Adv
        Behav Biol, Vol 25: Cholinergic Mechanisms. Eds G Pepeu, H Ladinsky, Plenum Publ Corp, NY, pp 695-704, 1981
237. Jakubovic A, McGeer EG, McGeer PL. Effect of cannabinoids and narcotics on gonadal functions. In: Neuroendocrine
        Regulation and Altered Behaviour. Eds PD Hrdina, RL Singhal, Croom Helm Ltd Publishers, London, US, pp 153-67,
        1981
236. McGeer EG, McGeer PL. Neurotoxins as tools in neurobiology. In: Int'l Rev Neurobiol, Vol 22. Eds JR Smythies, RJ
        Bradley, Academic Press Inc, NY, pp 173-204, 1981
235. McGeer PL, McGeer EG. Amino acid transmitters. In: Basic Neurochemistry, 3rd ed. Ed GJ Siegel, Little, Brown & Co,
        pp 233-53, 1981
234. McGeer PL, McGeer EG. Kainic acid as a selective lesioning agent. In: Glutamate: Transmitter in the Central Nervous
        System. Eds PJ Roberts, J Storm-Mathisen, GRS Johnston, John Wiley & Sons Ltd Publishers, Sussex, England, pp 55-
        75, 1981
233. McGeer EG, McGeer PL. Cholinergic mechanisms in central disorders. In: Neuropharmacology of Central Nervous
        System and Behavioral Disorders. Eds GC Palmer, Academic Press, pp 479-505, 1981
232. McGeer PL, McGeer EG. Neurotransmitters in the aging brain. In: The Molecular Basis of Neuropathology. Eds AN
        Davison, RH Thompson, Edward Arnold (Publishers) Ltd, London, UK, pp 631-48, 1981
231. McGeer EG, McGeer PL. Aging and neurotransmitter systems. In: Adv Biochem Psychopharmacol, Vol23 Ergot
        Compounds and Brain Function: Neuroendocrine and Neuropsychiatric Aspects. Eds M Goldstein, DB Calne, A
        Lieberman, MO Thorner, Raven Press, NY, pp 305-14, 1980
230. McGeer PL, McGeer EG, Inanen VT. Kainic acid and neurotransmitter interactions in the basal ganglia. In: Adv Biochem
        Psychopharmacol, Vol 24, Long-Term Effects of Neuroleptics. Eds F Cattabeni, G Racagni, PF Spano, E Costa, Raven
        Press, NY, pp 185-91, 1980
229. McGeer EG, McGeer PL. Biochemical mapping of specific neuronal pathways. In: Advances in Cellular Neurobiology,
        Vol 1. Eds S Fedoroff, L Hertz, Academic Press, NY, pp 347-72, 1980
228. McGeer PL, McGeer EG. Chemistry of mood and emotion. In: Annual Review of Psychology, Vol 31. Eds MR
        Rosenzweig, LW Porter, Annual Reviews Inc, CA, pp 273-307, 1980
227. McGeer PL, Jakubovic A. Ultrastructural and biochemical changes in CNS induced by marihuana. In: Marihuana:
        Biological Effects. Eds GG Nahas, WDM Paton, Pergamon Press, Oxford, pp 519-30, 1980
226. McGeer PL, McGeer EG. The control of movement by the brain. Trends Neurosci 3:III-IV, 1980
225. Peng JH, McGeer PL, Kimura H, Sung SC, McGeer EG. Purification and immunochemical properties of choline
        acetyltransferase from human brain. Neurochem Res 5:943-61, 1980
224. McGeer PL, McGeer EG, Campbell JR. Rotary effects of intracerebral tetanus toxin injections. Exp Neurol 67:363-7,
        1980
223. Kimura H, McGeer EG, McGeer PL. Metabolic alterations in an animal model of Huntington's disease using the 14C-
        deoxyglucose method. J Neural Transm Suppl 16:103-9, 1980
222. Kimura H, McGeer PL, Peng F, McGeer EG. Choline acetyltransferase containing neurons in rodent brain demonstrated 
        by immunohistochemistry. Science 208:1057-59, 1980
221. Zis AP, Marangos PJ, Parma A, McGeer EG. Changes in striatal neuron specific enolase (NSE) and non-neuronal
        enolase (NNE) following kainic acid administration. Brain Res 183:486-89, 1980
220. Vincent SR, McGeer EG. A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat
        striatum. Brain Res 184:99-108, 1980
219. Vincent SR, Kimura H, McGeer EG. The pharmacohistochemical demonstration of GABA-transaminase. Neurosci Lett
        16:345-48, 1980
218. McGeer EG, Singh EA. Possible cortico-hypothalamic glycinergic tract. Neurosci Lett 17:85-87, 1980
217. McGeer EG, Jakubovic A, Singh EA. Ethanol, baclofen and kainic acid neurotoxicity. Exp Neurol 69:359-64, 1980
216. Vincent SR, Lehmann J, McGeer EG. The localization of GABA-transminase in the striato-nigral system. Life Sci 27:595-
        601, 1980
215. Staines WA, Kimura H, Fibiger HC, McGeer EG. Peroxidase-labelled lectin as a neuroanatomical tracer: evaluation in a
        CNS pathway. Brain Res 197:485-90, 1980
214. Staines WA, Benjamin AM, McGeer EG. Cysteinesulfinate decarboxylase activity as an index of taurine-containing
        structures. J Neurosci Res 5:555-562, 1980
213. Vincent SR, Staines WA, McGeer EG, Fibiger HC. Transmitters contained in the afferents of the habenula. Brain Res 
        195:479-84, 1980
212. Jakubovic A, Lin D, McGeer EG. Protein and RNA synthesis in kainic acid-injected striata. Brain Res 163:189-94, 1979
211. Singh EA, McGeer EG. Postnatal activity of angiotensin converting enzyme in rat brain. Dev Neurosci 2:245-258, 1979
210. Vincent SR, McGeer EG. Kainic acid binding to membranes of striatal neurons. Life Sci 24:265-70, 1979
209. Sanberg PR, Staines W, McGeer EG. Chronic taurine effects on various neurochemical indices in control and kainic acid-
        lesioned neostriatum. Brain Res 161:367-70, 1979
208. Sanberg SR, Pisa M, McGeer EG. Strain differences and kainic acid neurotoxicity. Brain Res 166:431-35, 1979
207. McGeer EG, Scherer-Singler U, Singh EA. Confirmatory data on habenular projections. Brain Res 168:375-76, 1979
206. Scherer-Singler U, McGeer EG. Distribution and persistance of kainic acid in brain. Life Sci 24:1015-1022, 1979
205. McGeer EG, Singh EA. Inhibition of angiotensin converting enzyme by substance P. Neurosci Lett 14:105-8, 1979
204. Singh VK, McGeer EG. Binding of [3H]histamine to receptor sites in rat brain. Dev Neurosci 2:245-48, 1979
203. Vincent SR, McGeer EG. Structural specificity of high affinity [3H]glutamate uptake in striatal homogenates. J Pharm
        Pharmacol 31:703-4, 1979
202. Jakubovic A, McGeer EG. Narcotics and rat testicular metabolism. Mol Pharmacol 16:970-80, 1979
201. Purdy A, Hahn A, Barnett HJM, Bratty P, Ahmad D, Lloyd KG, McGeer EG, Perry TL. Familial fatal Parkinsonism with 
        alveolar hypoventilation and mental depression. Ann Neurol 6:523-31, 1979

200. McGeer EG. New biochemical approaches. In: Epilepsy: Neurotransmitter,  Behaviour and Pregnancy. Joint Publ Can
        League Against Epilepsy & Western Inst on Epilepsy (Ed JA Wada), 1979
199. Hattori T, McGeer PL, McGeer EG. Dendro-axonic neurotransmission. II. Morphological sites for the synthesis, binding
        and release of neurotransmitters in dopaminergic dendrites in the substantia nigra and cholinergic dendrites in the
        neostriatum. Brain Res 170:71-83, 1979
198. McGeer EG, McGeer PL, Vincent S. Morphine, naloxone and kainic acid neurotoxicity. Res Commun Chem Path
        Pharmacol 25:411-14, 1979
197. McGeer PL, McGeer EG, Innanen VT. Dendro-axonic neurotransmission. I. Evidence from receptor binding of
        dopaminergic and cholinergic agents. Brain Res 169:433-41, 1979
196. Jakubovic A, McGeer EG, McGeer PL. Effects of cannabinoids on testosterone and protein synthesis in rat testis Leydig
        cells in vitro. Mol Cell Endocrinol 15:41-50, 1979
195. Boyko WJ, Galabru CK, McGeer EG, McGeer PL. Thalamic injections of kainic acid produce myocardial necrosis. Life
        Sci 25:87-89, 1979
194. Brown WT, Sanberg PR, McGeer PL. Corticosteroids and chorea. Arch Neurol 36:452, 1979
193. Eccles JC, McGeer PL. Ionotropic and metabotropic neurotransmission. TINS 39-40, Feb 1979
192. Hattori T, McGeer PL. Fine structural analysis of the cortico-striatal pathway. J Comp Neurol 185:347-54, 1979
191. McGeer EG, McGeer PL. Localization of glutaminase in the rat neostriatum.
J Neurochem 32:1071-75, 1979
190. McGeer EG, McGeer PL, Hattori T, Vincent SR.
Kainic acid neurotoxicity and Huntington's disease. In: Advances in
        Neurology, Vol 23, Huntington's Disease. Eds TN Chase, NS Wexler, A Barbeau, Raven Press, NY, pp 577-91, 1979
189. McGeer PL
, McGeer EG. Interconnections of dopamine systems. In: The Neurobiology of Dopamine. Eds AS Horn, J
        Korf, BHC Westerink, Academic Press, London , pp 381-92, 1979
188. McGeer PL, McGeer EG, Innanen VT. Dendro-axonic neurotransmission and its implications for the therapy of
        Parkinson's disease. In: Advances in Neurology, Vol 24, The Extrapyramidal System and its Disorders. Eds TL Sourkes,
        PJ Bedard, Raven Press, NY, pp 225-33, 1979
187. McGeer PL
, McGeer EG. Use of the neurotoxic agents kainic acid and tetanus toxin in the extrapyramidal system. In:
        Advances in Cytopharmacology, Vol 3. Eds B Ceccarelli, F Clementi, Raven Press, NY , pp 437-46, 1979
186. McGeer PL
, McGeer EG. Central cholinergic pathways. In: Nutrition and the Brain, Vol 5. Eds A Barbeau, JH Growdon,
        RJ Wurtman, Raven Press, NY, pp 177-99, 1979
185. McGeer PL
, McGeer EG. Aging and neurotransmitter systems. In: Advances in Experimental Medicine and Biology, Vol
        113, Parkinson's Disease II: Aging and Neuroendocrine Relationships. Eds CE Finch, DE Potter, AD Kenny, Plenum
        Press, NY, pp 41-57, 1979
184. McGeer PL
, McGeer EG, Hattori T. Biochemical interactions in the basal ganglia. In: Progress in Brain Research, Vol 51.
        Eds M Cuenod, GW Kreutzbert, FE Bloom, Elsevier/North-Holland Biomedical Press, Amsterdam, pp 285-301, 1979
183. McGeer EG, McGeer PL
, Hattori T. Glutamate in the striatum. In: Glutamic acid: Advances in Biochemistry and
        Physiology. Eds LJ Filer Jr, S Garattini, MR Kare, WA Reynolds, RJ Wurtman, Raven Press, NY, pp 187-201, 1979
182. Jakubovic, A, McGeer EG, McGeer PL. Biochemical alterations induced by cannabinoids in the Leydig cells of the rat
         testis in vitro: effects on testosterone and protein synthesis. In: Marihuana: Biological Effects. Eds GG Nahas, WDM
         Paton, Pergamon Press, Oxford , pp 252-64, 1979
181. McGeer PL
, McGeer EG. Interactions of other neuronal systems with dopaminergic pathways: Pharmacological and
        anatomical aspects. In: The Neurobiology of Dopamine. Eds AS Horn, J Korf, B Westerink, Academic Press Inc Ltd
        (Lond), pp 381-92, 1979
180. McGeer EG, McGeer PL. GABA-containing neurons in schizophrenia, Huntington's chorea and normal aging. In: GABA-
        neurotransmitters, Alfred Benzo Symposium XII, Munksgaard, pp 340-56, 1978
179. Coyle JT, McGeer EG, McGeer PL
, Schwarcz R. Neostriatal injections: a model for Huntington's chorea. In: Kainic Acid
         as a Tool in Neurobiology. Eds EG McGeer, JW Olney, PL McGeer, Raven Press, NY, pp 139-60, 1978
178. McGeer EG, McGeer PL
, Hattori T, Singh VK. Immunohistochemistry of choline acetyltransferase. In: Progress in Brain
        Research, Vol 49: The Cholinergic Synapse. Ed S Tucek, Elsevier/North-Holland Biomedical Press, BV, pp 59-71, 1978
177. McGeer PL
, McGeer EG, Hattori T. Kainic acid as a tool in neurobiology. In: Kainic Acid as a Tool in Neurobiology. Eds
        EG McGeer, JW Olney, PL McGeer, Raven Press, NY, pp 122-38, 1978
176. McGeer PL
, McGeer EG. Intracerebral injections of kainic acid and tetanus toxin: possible models for the signs of chorea
        and dystonia. In: The Inherited Ataxias: Biochemical, Viral and Pathological Studies. Eds P Kark, R Rosenburg, LJ Schut,
        Raven Press, NY, pp 331-8, 1978
175. McGeer PL
, McGeer EG, Hattori T. Transmitters in the basal ganglia. In: Amino Acids as Chemical Transmitters. Ed F
        Fonnum, Raven Press, NY, pp 123-41, 1978
174. McGeer EG, McGeer PL.
Some factors influencing the neurotoxicity of intrastriatal injections of kainic acid. Neurochem
        Res 3:501-17, 978
173. Singh VK, McGeer EG, McGeer PL. Changes of [3H]colchicine binding and protein synthesis in the rat striatum following
        kainic acid lesions. Brain Res 146:195-9, 1978
172. McGeer EG, McGeer PL
, Singh EA. Kainate-induced degeneration of neostriatal neurons: dependency upon cortico-
        striatal tract. Brain Res 139:381-3, 1978
171. Jakubovic A, McGeer EG, McGeer PL. Effects of dl-methadone and morphine on developing chick embryo. Experimentia
        34:1617-18, 1978
170. Jakubovic A, McGeer EG, McGeer PL. Comparative inhibition of biosynthetic processes in rat testicular cells by d-, l-
        and dl-methadone Biochem Pharmacol 27:123-25, 1978
169. McGeer EG. Aging and neurotransmitter metabolism in the human brain. In: Alzheimer's Disease: Senile Dementia and
        Related Disorders, Vol 7: Aging (Eds R Katzman, RD Terry, KL Bick), Raven Press, NY, pp 431-44, 1978
168. Vincent SR, Hattori T, McGeer EG. The nigrotectal projection: a biochemical and ultrastructural characterization. Brain
        Res 151:159-64, 1978
167. Sung SC, Sanberg PR, McGeer EG. Cholinergic systems in muscle and brain in vitamin E-deficient rats.
Neurochem Res
        3:815-20, 1978
166. Nagy J, Vincent SR, Lehmann J, Fibiger HC, McGeer EG.
The use of kainic acid in the localization of enzymes in the
        substantia nigra. Brain Res 129:431-41, 1978
165 . Singh EA, McGeer EG. Angiotensin converting enzyme in kainic acid-injected striata. Ann Neurol 4:85-86, 1978
164. McGeer EG, Singh VK, Parkinson J, Scherer U. Effects of morphine on axonal transport in nigrostriatal neurons. Exp
        Neurol 59:342-50, 1978
163. Singh VK, McGeer EG. Choline acetyltransferase in developing rat brain and spinal cord. Brain Res 127:159-63, 1977
162. Hattori T, McGeer EG. Fine structural changes in the rat striatum after local injections of kainic acid. Brain Res 129:174-
        80, 1977
161. McGeer EG, Scherer U, Singh EA. Axonal transport in the habenula-interpeduncular tract. Exp Neurol 57:682-86, 1977
160. McGeer PL
, McGeer EG. Possible changes in striatal and limbic cholinergic systems in schizophrenia. Arch Gen
        Psychiatry 34:1319-23, 1977
159. Jakubovic A, McGeer PL. Biochemical changes in rat testicular cells in vitro produced by cannabinoids and alcohol.
        Metabolism and incorporation of labeled glucose amino acids and nucleic acid precursor. Toxicol Appl Pharmacol 41:473-
        86, 1977
158. McGeer PL
, Brown WT, Zeldowicz L. Lack of effect of g-hydroxy-butyrate in Huntington's chorea. Can Psychiatr Assoc
        J 22:87-90, 1977
157. McGeer PL.
The unbalanced brain. The Sciences 17:14-17, 1977
156. McGeer PL, McGeer EG, Scherer U, Singh VK. A glutamatergic cortico-striatal path? Brain Res 238:369-73, 1977
155. Singh VK, McGeer PL. Studies on choline acetyltransferase isolated from human brain.
Neurochem Res 2:281-291, 1977
154. Hattori T, McGeer EG, Singh VK, McGeer PL.
Cholinergic synapse of the interpeduncular nucleus. Exp Neurol 55:666-
        79, 1977
153. Hattori T, McGeer PL. Electron microscopic autoradiography on D9-[3H]tetrahydrocannabinol localization in brain tissue.
        Toxicol Appl Pharmacol 39:307-311, 1977.
152. McGeer EG, McGeer PL
, Suzuki J. Aging and extrapyramidal function. Arch Neurol 34:33-35, 1977
151. McGeer PL
, McGeer EG, Hattori T. Dopamine-acetylcholine-GABA neuronal linkages in the extrapyramidal and limbic 
        systems. In: Advances in Biochemical Psychopharmacology, Vol 16. Eds E Costa, GL Gessa, Raven Press, NY, pp 397-
        402,1977
150. Jakubovic A, McGeer PL.
In vitro inhibition of protein and nucleic acid synthesis in rat testicular tissues by cannabinoids. In:
        Marihuana: Chemistry, Biochemistry and Cellular Effects (ed GG Nahas), Springer-Verlag, New York , 1976, pp 223-
        241
149. McGeer PL
, McGeer Eg. Aging, disease and extrapyramidal function. For the Conference on "Problems in Extrapyramidal
        Dysfunction," Cagliari Gardone, Italy , May 1976
148. McGeer PL
, Hattori T, Singh VK, McGeer EG. Cholinergic systems in extrapyramidal function. In: The Basal Ganglia. Ed.
        MD Yahr, Raven Press, NY, pp 213-22, 1976
147. McGeer EG, McGeer PL. Neurotransmitter metabolism in the aging brain. In: The Neurobiology of Aging, Vol 33.
        Eds RD Terry, S Gershon, Raven Press, NY, pp 389-403, 1976

146. McGeer PL, Grewaal DS, McGeer EG. Effect on extrapyramidal GABA levels of drugs which influence dopamine and
        acetylcholine metabolism. In: Advances in Parkinsonism. Eds W Birkmayer, O Hornykiewicz, Editions Roche, Basel , pp
        132-40, 1976
145.
McGeer PL, McGeer EG. The GABA system and function of the basal ganglia in Huntington's disease. In: GABA in
        nrvous System Function. Eds E Roberts, RN Chase, D Tower, Kroc Fdn Series, Vol 5, Raven Press, NY, pp 487-96,
        1976
144. Hattori T, Singh VK, McGeer EG, McGeer PL. Immunohistochemical localization of choline acetyltransferase containing
        neostriatal neurons and their relationship with dopaminergic synapses. Brain Res 102:164-73, 1976
143. Jakubovic A, McGeer PL. Effects of D9-tetrahydrocannabinol and ethanol on body weight protein and nucleic acid
        synthesis in chick embryos. J Toxicol Environ Health 1:441-447, 1976.
142. McGeer EG, Innanen VT , McGeer PL. Evidence on the cellular localization of adenyl cyclase in the neostriatum. Brain
        Res 118:356-58, 1976
141. McGeer EG, Parkinson J, Mcgeer PL. Neonatal enzyme development in the interpeduncular nucleus and surrounding
        ventral tegmentum. Exp Neurol 53:109-14, 1976
140. Hattori T,
McGeer PL, McGeer EG. Synaptic morphology in the neostriatum of the rat: possible serotonergic synapse.
        Neurochem Res 1:451-67, 1976
139. McGeer EG, McGeer PL. Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic
        acid and kainic acids. Nature 263:517-19, 1976
138.
McGeer PL, McGeer EG. Enzymes associated with the metabolism of catecholamines, acetylcholine and GABA in human
        controls and patients with Parkinson's disease and Huntington's chorea. J Neurochem 26:65-76, 1976
137. Hattori T, Fibiger HC, McGeer PL. Demonstration of a pallido-nigral projection innervating dopaminergic neurons. J
        Comp Neurol 162:487-504, 1975
136. Singh VK, McGeer EG,
McGeer PL.Two immunologically different choline acetyltransferase in human neostriatum. Brain
        Res 96:187-91, 1975
135.
McGeer PL, McGeer EG. Evidence for glutamic acid decarboxylase-containing interneurons in the neostriatum. Brain Res
        91:331, 1975
134.
McGeer PL, Hattori T, McGeer EG. Chemical and autoradiographic analysis of GABA transport in Purkinje cells of the
        cerebellum. Exp Neurol 47:26-41, 1975
133. McGeer EG, Hattori T, McGeer PL. Electron microscopic localization of labelled norepinephrine transported in nigro-
        striatal neurons. Brain Res 86:478-82, 1975
132. McGeer EG,
McGeer PL, Grewaal DS, Singh VK. Striatal cholinergic interneurons and their relation to dopaminergic
        nerve endings. J Pharmacol (Paris) 6:143-52, 1975
131. Hattori T,
McGeer PL, Singh VK, McGeer EG, Fibiger HC. 6-hydroxydopamine as a tool for demonstrating connections
        in the basal ganglia. In: Chemical Tools in Catecholamine Research, Vol 1. Eds G Johnson, T Malmfors, Ch Sachs, North-
        Holland Publishing Co, Amsterdam , pp 141-8, 1975
130. McGeer PL, McGeer EG, Fibiger HC. Choline acetylase and glutamic acid decarboxylase in Huntington's chorea. In:
        Yearbook of  Neurology and Neurosurgery. Eds RN De Jong, O Sugar, pp 152-9, 1975
129. McGeer EG, McGeer PL. Age changes in the human brain for some enzymes associated with metabolism of 
        catecholamines, GABA and acetylcholine. In: Neurobiology of Aging, Vol 16: Advances in Behavioral Biology, Eds JM
        Ordy, KR Brizzee, Plenum Press, NY, pp 287-306, 1975
128. McGeer EG, Searl K, Fibiger HC. Chemical specificity of dopamine transport in the nigro-neostriatal projection. J
        Neurochem 24:282-288, 1975
127. McGeer EG, Maler L. GABA accumulation by embryonic chick tectum. Dev Biol 47:464-65, 1975
126. Fibiger HC, McGeer EG. Accumulation and axoplasmic transport of dopamine but not of amino acids by axons of the
        nigro-neostriatal projection. Brain Res 73:366-69, 1974
125. McGeer EG, Maler L, Fitzsimmons RC. Comparative enzymatic development in chick embryonic brain areas. Dev Biol  
        38:165-74, 1974
124. Grewaal DS, Fibiger HC, McGeer EG. Influence of 6-hydroxydopamine lesions on rat striatal acetylcholine levels. Brain
        Res 73:372-75, 1974
123.
McGeer PL, Hattori T, Fibiger HC. Ascending and descending neurons by electron microscopic autoradiography.
        In: Neuropsychopharmacology. Proc of 9th Cong of the Collegium Internationale Neuropsychopharmacologicum. Eds JR
        Roissier, H Hippius, T Pichot, Excerpta Medica, Amsterdam, American Elsevier Publishing Co, NY, pp 412-24, 1974
122.
McGeer PL, Fibiger HC, Maler L, Hattori T, McGeer EG. Evidence for descending pallido-nigral GABA-containing
        neurons. In: Advances in Neurology, Vol 5. Eds FM McDowell, A Barbeau, Raven Press, NY, pp 153-60, 1974
121.
McGeer PL, Hattori T, Fibiger HC. Ascending and descending connections of nigral dopaminergic neurons by electron 
        microscopic autoradiography. In: Pharmacology and Biochemistry of the Nigro-Striatal System. Ed J Glowinski, Excerptia
        Medica, pp 412-24, 1974
120. McGeer PL, Fibiger HC, Hattori T, Singh VK, McGeer EG, Maler L. Biochemikcal neuroanatomy of the basal ganglia.
        In: Neurohumoral Coding and Brain Function, Advances in Behavior and Biology, Vol 10.
Eds RD Myers, RR Drucker-
        Colin, Plenum Press, NY, pp 27-48, 1974
119.
McGeer PL, Grewaal, DS, McGeer EG. Influence of non-cholinergic drugs on rat striatal acetylcholine levels. Brain Res
        80:211-17, 1974
118. Singh VK,
McGeer PL.Cross-immunity of antibodies to human choline acetyltransferase in various vertebrate species.
        Brain Res 82:356-59, 1974
117. Singh VK, McGeer PL. Antibody production to choline acetyltransferase purified from human brain. Life Sci 15:901-13,
        1974
116. McGeer PL, McGeer EG, Singh VK, Chase WH. Choline acetyltransferase localization in the central nervous system by
        immunohistochemistry. Brain Res 81:373-9, 1974
115.
McGeer PL, Hattori T. Biochemical neuroanatomy and psychiatric drugs. Fukushima Medical Journal 23:129-50, 1974
114. Jakubovic A, McGeer PL. Intracellular distribution of 3H-d8-THC in rat organs after intraventricular administration. Res
        Commun Chem Path Pharmacol 9:197-200, 1974
113. Hattori T, McGeer PL. Electron microscopic identification of cholinesterase-containing structures in the corpus striatum by
        disopropylfluorophosphate uptake. Exp Neurol 45:541-8, 1974
112. Singh VK, Fibiger HC, McGeer PL. Effects of 6-hydroxy-dopamine on the nature of proteins undergoing axoplasmic 
        transport in nigroneostriatal neurons.
J Neurochem 23:601-4, 1974
111. Singh VK, Fibiger HC, McGeer PL, McGeer EG.
Analysis of proteins undergoing axonal transport in nigro-striatal
        neurons in the rat. J Neurochem 2:119-24, 1974
110. Jakubovic A, Tait M, McGeer PL. Excretion of THC and its metabolites in mothers' milk. Toxicol Appl Pharmacol 28:38-
        43, 1974
109. McGeer EG, McGeer PL. Properties of brain tyrosine hydroxylase. In: New Concepts in Neurotransmitters Regulation 
        (Ed AJ Mandell), Plenum Press, NY, pp 53-68, 1973
108.
McGeer PL, McGeer EG. Neurotransmitter synthetic enzymes. In: Progress in Neurobiology, Vol 2, Part 1. Eds GA
        Kerkut, JW Phillis, Pergamon Press, Oxford & NY, pp 69-117, 1973
107. McGeer EG, McGeer PL. Amino acid hydroxylase inhibitors. In: Metabolic Inhibitors. Ed Hochster, Kates, Quastel,
        Academic Press, NY, pp  45-127, 1973
106. Fibiger HC, Zis AP, McGeer EG. Feeding and drinking deficits after 6-hydroxydopamine administration in the rat:
        similarities to the lateral hypothalamic syndrome. Brain Res 5:135-48, 1973
105. McGeer EG. Tryptophan hydroxylase inhibitors other than p-chlorophenylalanine. In: Serotonin and Behavior, Academic
        Press, New York , pp 55-59, 1973
104. Fibiger HC, McGeer EG, Atmadja S. Axoplasmic transport of dopamine in nigro-striatal neurons. J Neurochem 21:373-
        85, 1973
103. Corcoran ME, Fibiger HC, McGeer EG, Wada J. Potentiation of leptazol seizures by 6-OHDA. J Pharm Pharmacol 
        5:497-99, 1973
102. Fibiger HC, McGeer EG. Increased axoplasmic transport of 3H-dopamine in nigro-neostriatal neurons after reserpine. 
        Life Sci 13:1565-71, 1973
101. McGeer PL, McGeer EG, Fibiger HC. Glutamic acid decarboxylase and choline acetylase in Huntington's chorea and
        Parkinson's disease. The Lancet 15:623-4, 1973
100. McGeer PL, McGeer Eg, Fibiger HC. Choline acetylase and glutamic acid decarboxylase in Huntington's chorea. 
        Neurology 23:912-17, 1973
  99. Hattori T, Fibiger HC, McGeer PL, Maler L. Analysis of the fine structure of the dopaminergic nigro-striatal pathway by 
        electron microscopic autoradiography. Exp Neurol 41:599-611, 1973
  98. Jakubovic A, Hattori T, McGeer PL. Radioactivity in suckled rats after giving 14C-tetrahydrocannabinol to the mother.
        Eur J Pharmacol 22:221-3, 1973
  97. Maler L, Fibiger HC, McGeer PL. Demonstration of nigro-striatal projection by silver staining after nigral injections of 6-
        hydroxydopamine. Exp Neurol 40:505-15, 1973
  96. Hattori T, Jakubovic A,
McGeer PL.The effect of cannabinoids on the number of nuclear membrane-attached ribosomes
        in the infant rat brain. Neuropharmacology 12:995-9, 1973
  95. McGeer EG, Fibiger HC,
McGeer PL, Brooke S. Temporal changes in synthesizing enzymes of rat extrapyramidal
        structures after hemitransections or hydroxydopamine administration. Brain Res 52:289-300, 1973
  94. Hattori T, McGeer PL. Synaptogenesis in the caudate-putamen of infant rat.
Exper Neurol 38:70-79, 1973
  93. Hattori T, McGeer PL, Fibiger HC, McGeer EG.
On the source of GABA-containing terminals in the substantia nigra:
        electron microscopic 6-autoradiographic and biochemical studies. Brain Res 54:103-14, 1973
  92. Hattori T, Jakubovic A, McGeer PL. Reduction in number of nuclear membrane-attached ribosomes in infant rat brain
        following acute d9-tetrahydrocannabinol administration. Exp Neurol 36:207-11, 1972
  91. MacFadyen DJ, Picton TW, Zeldowicz L, McGeer PL. Amantadine-HCl in the treatment of Parkinson's disease: a
        controlled trial. J Clin Pharmacol 12:274-9, 1972
  90. Fibiger HC, Purdritz RE,
McGeer PL, McGeer EG. Axonal transport in nigro-striatal and nigro-thalamic neurons: effects
        of medial forebrain bundle lesions and 6-hydroxydopamine.
J Neurochem 19:1697-1708, 1972
  89. Fibiger HC, Purdritz RE, McGeer PL, McGeer EG.
Axonal transport in nigro-striatal neurons. Nature 237:177-78, 1972
  88. Jakubovic A, McGeer PL. Inhibition of rat brain protein and nucleic acid synthesis by d9-tetrahydrocannabinol in vitro.
        Can J Biochem 50:654, 1972
  87.
McGeer PL, Zeldowicz L, McGeer EG. A clinical trial of folic acid in Parkinson's disease. Can Med Assoc J 196:145, 
        1972
  86. McGeer EG, Fibiger HC, McGeer PL. Brain enzymes in amantadine-treated rats. Biochem Med 6:189-91, 1972
  85. McGeer EG, Fibiger HC,
McGeer PL, Wickson V. Aging and brain enzymes. Exp Geront 6:391-6, 1972
  84. 
McGeer PL, McGeer EG, Fibiger HC, Wickson V. Neostriatal choline acetylase and cholinesterase following selective 
        brain lesions. Brain Res 35:308-14, 1971
  83. McGeer EG,
McGeer PL, Wada JA. Distribution of tyrosine hydroxylase in human and animal brain.
J Neurochem 
        18:1647-58, 1971
  82. Fibiger HC, Fox M, McGeer EG, McGeer PL.
The effect of amantadine on spontaneous locomotor activity in the rat. J 
        Pharm Pharmacol 23:774, 1971
  81. McGeer PL. Tyrosine hydroxylase and Parkinsonism. The Lancet ii:165, 1971
  80. McGeer PL, McGeer EG, Wada JA. Glutamic acid decarboxylase in Parkinson's disease and epilepsy. Neurology 
        21:1000-7, 1971
  79. McGeer PL, McGeer EG, Wada JA, Jung E. Effects of globus pallidus lesions and Parkinson's disease on brain glutamic 
         acid decarboxylase. Brain Res 32:425-31, 1971
   78.
McGeer PL, McGeer EG. Cholinergic enzyme systems in Parkinson's disease. Arch Neurol 25:265-8, 1971
   77.
McGeer PL.The chemistry of mind. Amer Scientist 59:221-9, 1971
   76. McGeer EG, Fibiger HC, Wickson V. Differential development of caudate enzymes in neonatal rat. Brain Res 32:433-
         40, 1971
   75. Fibiger HC, McGeer EG. Effect of acute and chronic methamphetamine treatment on tyrosine hydroxylase activity in
         brain and adrenal medulla. Eur J Pharmacol 16:176, 1971
   74. McGeer EG. Gelatin capsules as disposable wells for CO2 absorption. Anal Biochem 35:300-1, 1970
   73. Chalmers A, McGeer EG, Wickson V, McGeer PL. Distribution of glutamic acid decarboxylase in the brains of various
         mammalian species. Comp Gen Pharmacol 1:385-90, 1970
   72. Chalmers A, McGeer EG, Wickson V, McGeer PL. Distribution of glutamic acid decarboxylase in the brains of various
         mammalian species. Comp Gen Pharmacol 1:385-90, 1970
   71.
McGeer PL, Wada JA, Gibson S, Loeser C, McGeer EG. Tyrosine hydroxylase levels in the cat caudate and basal 
         forebrain following selective midbrain lesions. 2nd Int'l Congr Neurogenetics & Neuro-ophthalmology, Montreal , Sept
        17-21, 1967, pp 194-305. Excerpta Medical Int'l Congr Series No 175, 1970
   70. Gibson S, McGeer EG, McGeer PL. Effect of selective inhibitors of tyrosine and tryptophan hydroxylases on self-
         stimulation in the rat. Exp Neurol 27:283-90, 1970
   69. Gibson S, McGeer EG, McGeer PL. Catecholamine metabolism in cold-exposed rats.
J Neurochem 16:1491-3, 1969
   68. McGeer EG, Ikeda H, Asakura T, Wada JA.
Lack of abnormality in brain aromatic amines in rats and mice susceptible to
         audiogenic seizure. J Neurochem 16:945-50, 1969
   67. McGeer EG, Peters DAV. In vitro screen of inhibitors of rat brain serotonin synthesis. Can J Biochem 47:501-6, 1969
   66. McGeer EG, Wada JA, Terao A, Jung E. Amine synthesis in various brain regions with caudate or septal lesions. Exp
         Neurol 24:277-84, 1969
   65. Jones L,
McGeer PL, Greiner A. Metabolism of exogenous melatonin in schizophrenic and non-schizophrenic volunteers.
         Clin Chim Acta 26:281-5, 1969
   64. Poirier L, McGeer EG, Larochelle L, McGeer PL, Bedard P, Boucher R. The effect of brain stem lesions on tyrosine and
         tryptophan hydroxylases in various structures of the telencephalon of the cat. Brain Res 14:147-55, 1969
   63. Jones RL, Bory P, Brown WT, McGeer PL. Failure to detect p-methoxy-phenylethylamine derivatives in human urine.
         Can J Biochem 47:185, 1969
   62. Peters DAV,
McGeer PL, McGeer EG. The distribution of tryptophan hydroxylase in cat brain. J Neurochem 15:1431,
         1968
   61. McGeer EG, Peters DAV, McGeer PL. Inhibition of rat brain tryptophan hydroxylase by 6-halotryptophans. Life Sci
         7:605-16, 1968
   60. Peters DAV, McGeer PL. Inhibition of purine biosynthesis by analogues of 4(5)-aminoimidazole-5(4)-carboxamide.
         Can J Physiol Pharmacol 46:195-200, 1968
   59. Brown WT,
McGeer PL, Moser I. Lack of psychotomimetic effect of paramethoxy-phenylethylamine and 3,4-
         dimethoxyphenylethylamine in man. Can Psychiat Assoc J 13:91-2, 1968
   58. McGeer EG, Gibson S, Wada J, McGeer PL. Distribution of tyrosine hydroxylase activity in adult and developing brain. 
         Can J Biochem 45:1943-52, 1967
   57. McGeer EG,
McGeer PL, Peters DAV. Inhibition of brain tyrosine hydroxylase by 5-halotryptophans. Life Sci 6:2221-
         32, 1967
   56. McGeer EG, Gibson S,
McGeer PL.Some characteristics of brain tyrosine hydroxylase. Can J Biochem 45:1557-63, 
        1967
   55. McGeer EG,
McGeer PL.In vitro screen of inhibitors of rat brain tyrosine hydroxylase. Can J Biochem 45:115-31, 1967
   54. Wada JA, Ikdea H, McGeer EG. The susceptibility to audiogenic stimuli of rats treated with methionine sulfoximine and
         various psychoactive agents. Exp Neurol 18:327-37, 1967
   53. Wada JA, McGeer EG. Central aromatic amines and behavior. III. Correlative analysis of conditioned approach
          behavior and brain levels of serotonin and catecholamines in monkeys. Arch Neurol 14:129-42, 1966
   52. Newman MA,
McGeer PL.The capture and care of a killer whale, Orcinus orca, in British Columbia . Zoologica 51:59-
         70, 1966
   51. Newman MA,
McGeer PL.A killer whale, Orcinus orca, at Vancouver aquarium, Int'l Zoo Yearbook 6;257-9, 1966
   50. McGeer EG, McGeer PL. Circadian rhythm in pineal tyrosine hydroxylase. Science 143:73-74, 1966
   49. Sen NP, McGeer PL. Increased excretion of formino-glutamic acid by vitamin B12 deficient rats after a load of Dl-
         homocystine or oxidized gluthatione. Can J Biochem 44:286-91, 1966
   48. Sen NP, McGeer PL. Preparation and properties of some compounds of biological interest. J Chromatog 20:147-9,
        1965
   47.
McGeer PL, Bagchi SP, McGeer EG. Subcellular localization of tyrosine hydroxylase in beef caudate nucleus. Life Sci
         4:1859-1867, 1965
   46. McGeer pL, Sen NP, Grant DA. Excretion of 4(5)-amino-5(4)-imidazolecarboximide and formino-L-glutamic acid in
         folic acid and vitamin B12 deficient rats. Can J Biochem 43:1367-74, 1965
   45. Hebb CO , Ling GM, McGeer EG,
McGeer PL, Perkins D. Effect of locally applied homicholinium on the acetylcholine 
         content of the caudate nucleus. Nature 204:1309-11, 1964
   44. McGeer EG, Clark R. Values of some catecholamines, precursors and metabolites. J Chromatogr 14:107-111, 1964
   43.
McGeer PL, McGeer EG. Formation of adrenaline by brain tissues. Biochem Biophys Res Commun 17:502, 1964
   42. Herbert V, Streiff RR, Sullivan LW, McGeer PL. Deranged purine metabolism manifested by
         aminoimidazolecarboxamide  excretion in megaloblastic anaemias, haemolytic anaemia and liver disease. The Lancet ii:45-
         46, 1964
   41. Bagchi SP,
McGeer PL.Some properties of tyrosine hydroxylase from the caudate nucleus. Life Sci 3:1195-1200, 1964
   40. Herbert V, Streiff R, Sullivan L, McGeer P. Accumulation of a purine intermediate (aminoimidazolecarboxamide) (AIC)
         in megaloblastic anemias associated with vitamin B12 deficiency, folate deficiency with alcoholism, and liver disease. Fed
         Proc 23:188, 1964 (abst)
   39. McGeer PL, Zeldowicz LR. Administration of dihydroxyphenylalanine to Parkinsonian patients. Can Med Assoc J
         90;463-6, 1964
   38. Sen NP,
McGeer PL.4-Methoxyphenylethylamine and 3,4-dimethoxyphenylethylamine in human urine. Biochem Biophys
         Res Commun 14:227-32, 1964
   37.
McGeer PL.The distribution of histamine in cat and human brain. In: Comparative Neurochemistry. Ed D Richter, 
         Pergamon Press, NY , pp 387-91, 1964
   36. McGeer EG, Ling GM, McGeer PL. Conversion of tyrosine to catecholamine by cat brain in vivo. Biochem Biophys Res
        Commun 13:291-6, 1963
   35. Sen NP, McGeer PL. Gas chromatography of phenolic and catecholic amines as the trimethylsilyl ethers. Biochem
         Biophys Res Commun  13:390-3, 1963
   34. McGeer PL. Central amines and extrapyramidal functions. J Neuropsychiatry 4:247-50, 1963
   33. McGeer PL, McGeer EG, WAda JA. Central aromatic amine levels and behavior. II. Serotonin and catecholamine levels
         in various cat brain areas following administration of psychoactive drugs or amine precursors. Arch Neurol 9:81-9, 1963
   32. Wada JA, Wrinch J, Hill D,
McGeer PL, McGeer EG. Central aromatic amine levels and behavior. I. Conditioned 
         avoidance response in cats, following administration of psychoactive drugs or amine precursors. Arch Neurol 9:69-80, 
         1963
   31. Iyer NT ,
McGeer PL, McGeer EG. Conversion of tyrosine to catecholamines by rat brain slices. Can J Biochem Physiol
         41:1565-70, 1963
   30.
McGeer PL, Wada JA, McGeer EG. Correlations between aromatic amine levels and behavioral tests following
         administration of  psychoactive drugs. Rec Adv Biol Psychiat 5:228-36, 1963
   29. McGeer PL, McGeer EG, Boulding JE. Excretion of 4-amino-5-imidazolecarboxamide by mental patients. Arch Gen 
         Psychiat 8:428:18-22, 1963
   28.
McGeer PL, McGeer EG. Effects of amethopterin and vincaleukoblastine on urinary 4-amino-5-imidazolecarboxamide.
         Biochem Pharmacol 12:293-302, 1963
   27. Sen NP,
McGeer PL, Paul RN. Imidazoleproprionic acid as a urinary metabolite of L-histidine. Biochem Biophys Res
        Commun 9:257-61, 1962
   26. McGeer EG, McGeer PL. Catecholamine content of spinal cord. Can J Biochem 40:1141-51, 1962
   25. Nichol C,
McGeer PL, Miller JR. Creatinine kinase in normal and dystrophic mouse muscle. Can J Biochem Physiol
         40:443-7, 1962
   24. Miller JR,
McGeer PL, Nichol C. Serum creatinine kinase and carrier detection in muscular dystrophy. The Lancet ii:201,
         1962
   23. McGeer PL. Mind, drugs and behavior. Amer Scientist 50:322-38, 1962
   22. McGeer EG, McGeer PL, Miller JR, Derry D, Nichol C. Excretion of 4-amino-5-imidazolecarboxamide and creatinine: 
         creatinine ratios in human and mouse muscular dystrophy. Can J Biochem Physiol 40:13-23, 1962
   21. Tischler B, McGeer EG. Effects of folic acid on the phenylalanine tolerance test in phenylketonuria. Can Med Assoc J
         87:1331-32, 1962
   20. Tischler B, Gibson WC, McGeer EG, Nuttall J. Degrees of mental retardation of phenylketonuria. Am J Ment Def
         65:726-38, 1961
   19. McGeer EG,
McGeer PL, McLennan H. Inhibitory properties of the catecholamines. Nature 192:563, 1961
   18. McGeer PL, Boulding JE, Gibson WC, Foulkes RG. Drug-induced extrapyramidal reactions. Treatment with
         diphenhydramine hydrochloride and dihydroxyphenylalanine. JAMA 177:665-70, 1961
   17. McGeer EG,
McGeer PL, McLennan H. The inhibitory action of 3-hydroxytryptamine, g-gaminobutyric acid (GABA)
         and some other compounds towards the crayfish stretch receptor neuron. J Neurochem 8:36-49, 1961
   16.
McGeer PL, McGeer EG, Nasselback R. Preliminary survey of 4-amino-5-imidazolecarboxamide excretion in leukemia
         and other illnesses. Can Med Assoc J 85:437-49, 1961
   15.
McGeer PL, McGeer EG. Aromatic urinary excretion in schizophrenics. In: Chemical Pathology of the Nervous System.
         Proc 3rd Int'l Neurochem Symposium, Strasbourg, 1958 (Ed J Folchi-Pi), Pergamon Press, NY , pp 589-99, 1961
   14. McGeer PL, McGeer EG, Wood AJ. Excretion of 4-amino-5-imidazolecarboxamide by various animal species. Can J
         Comp Med 25:211-212, 1961
   13.
McGeer PL, McGeer EG, Griffin MC. Excretion of 4-amino-5-imidazolecarboxamide in human urine. Can J Biochem
         Physiol 39:592-603, 1961
   12. McGeer EG, Robertson MC, McGeer PL. Chromatographic characteristics of some aromatic compounds of biological
         interest. Can J Biochem Physiol 39:605-27, 1961
   11.
McGeer PL, McGeer EG, Feldstein A, Hoagland H, Riviera MR, Freeman H. Metabolism of radioactive serotonin in
         psychotics treated with a MAO inhibitor. J Neuropsychiatry 1:274-5, 1960
   10. McGeer PL, McKenzie AD. Strangulation of the appendix epipioica: A series of 11 cases. Can J Surg 3:252-8, 1960
     9. Smith DM, Paul RM, McGeer EG,
McGeer PL.A general chromatographic survey of aromatic compounds obtained 
         from urine. Can JBiochem Physiol 37:1493-1515, 1959
     8. McGeer EG, McGeer PL. Physiological effects of schizophrenic body fluids. J Ment Sci 105:1-16, 1959
     7. McGeer EG, Tischler B. Vitamin B6 and mental deficiency. The effects of large doses of B (pyridoxine) in
         phenylketonuria. Can J Biochem Physiol 37:485-491, 1959
     6. Tischler B, McGeer EG. Vitamin B6 in mental deficiency: Xanthurenic acid excretion in phenylketonurics. Can Med
         Assoc J 78:954-55, 1958
     5. McGeer EG, Brown WT, McGeer PL. Aromatic metabolism in schizophrenia. II. Bidimensional urinary chromatograms.
         J Nerv Ment Dis  125:176-80, 1957
     4. McGeer PL, McNair FE, McGeer EG, Gibson WC. Aromatic metabolism in schizophrenia. I. Statistical evidence for
         aromaturia. J Nerv Ment  Dis 125:166-75, 1957
     3. 
McGeer PL, Aromatic metabolism and schizophrenia. Conference on the Biochemistry of Mental Illness, The University
         of British Columbia , June 19-21, 1957. UBC Publ Biological Sciences Series No 4, pp 34-35
     2. McGeer PL, McGeer EG, Boulding JE. Relation of aromatic amino acids to excretory pattern of schizophrenics. Science
         123:1078-80, 1956
     1. McGeer PL, McGeer EG, Gibson WC. Aromatic excretory pattern of schizophrenics. Science 123:1029-30, 1956

Books

McGeer PL, Eccles JC, McGeer EG. Molecular Neurobiology of the Mammalian Brain. 2nd ed, Plenum Press, New York , 1987
McGeer PL
, Eccles JC, McGeer EG. Molecular Neurobiology of the Mammalian Brain. Plenum Press, New York,
1979
McGeer PL.
Politics in Paradise, Peter Martin Associates, Toronto , 1972





Publications of J. Miklossy

1. Danko M, Miklossy J. The role of sodium ions in the potassium sensitization effect of Veratrin. Doctoral Thesis, Part I;
   1969.Library of the University Medical School of Debrecen, Hungary.
2. Miklossy J, Molnar M. Differentiation between fast and slow acetylcholine potentials in striated muscle of frog. Doctoral
    thesis, Part II; 1970. Library of the University Medical School of Debrecen, Hungary.
3. Miklossy J, Molnar L. The prognostic value of the non-protein nitrogen (NPN) content in the serum and the cerebrospinal
    fluid.Ideggyogyàszati Szemle 1975;18:25-32.
4. Miklóssy J , Molnár L, Rochlitz Sz. The prognostic value of the non-protein nitrogen (NPN) content in the serum and the
    cerebrospinal fluid. Eur Arch Psych Clin Neurosci, 1976 ;222 :77-85.
5. Miklossy J, Molnar L, Rochlitz Sz. The prognostic value of the non-protein nitrogen (CPN) content in serum and the
    cerebrospinal fluid. Arch Psychiat Nervenkr 1976;222:77-85.
6. Bogousslavsky J, Miklossy J, Regli L, Deruaz J, Despland PA. One-and-a-half syndrome in ischemic locked-in state: a
    clinico-pathological study. J Neurol Neurosurg Psychiatry 1984;47:927-935.
7. Cruchaud A, Deruaz JP, Miklossy J. Fièvres, myalgies, polyneuropathie chez une patiente de 69 ans. Méd et Hyg 
    1985;43:2462-2468.
8. Bogousslavsky J, Miklossy J, Regli F, Deruaz JP, Regli F, Assal G. Unilateral left paramedian infarction of thalamus and 
    midbrain: a clinico-pathological study. J Neurol Neurosurg and Psychiatry 1986;49:686-694.
9. Bogousslavsky J, Miklossy J, Deruaz JP, Assal G, Regli F. Lingual and fusiform gyri in visual processing: a clinico-pathologic
    study of superior altitudinal hemianopia. J Neurol Neurosurg and Psychiatry. 1987; 50:607-614.
10. Miklossy J, Van der Loos H. Cholesterol ester crystals in polarized light show pathways in the human brain. Brain Res
      1987;426:377-380.
11. Bogousslavsky J, Miklossy J, Regli F, Deruaz JP, Assal G, Delaloye B. Subcortical neglect: Neuropsychological, SPECT,
      and neuropathological correlations with anterior choroidal artery territory infarction. Ann Neurol 1988;23:448-452.
12. Bogousslavsky J, Miklossy J, Deruaz JP, Regli F. Thalamic aphasia. Neurology 1988;38:1662.
13. Lang W, Miklossy J, Deruaz JP, Pizzolato GP, Probst A, Schaffner T, Gessaga E, Kleihues P. Neuropathology of the
      acquired immune deficiency syndrome (AIDS): a report of 135 consecutive autopsy cases form Switzerland. Acta
      Neuropathol 1989;77:379-390.
14. Pecoud A, Essinger A, Miklossy J, Ribaux C. Cachexie, douleurs et faiblesse musculaires chez une femme de 69 ans.
      Cachexia, pain and muscle weakness in a 69-year-old woman Schweiz Med Wochenschr 1989;119:407-415.
15. Bogousslavsky J, Miklossy J, Regli F, Janzer RC. Vertical gaze palsy and selective unilateral infarction of the rostral
      interstitial nucleus of the medial longitudinal fasciculus (riMLF). J. Neurol. Neurosurg. Psychiatry 1990;53:67-71
16. Clarke S, Miklossy J. Occipital cortex in man: organization of callosal connections, related myelo- and cytoarchitecture,
      and putative boundaries of functional visual areas. J. Comp. Neurol. 1990;298:188-214.
17. W. Lang, J. Miklossy, J. P. Deruaz, G. P. Pizzolato, A. Probst, T. Schaffner, E. Gessaga and P. Kleihues Neuropathology
      of the acquired immune deficiency syndrome (AIDS): a report of 135 consecutive autopsy cases from Switzerland Acta
      Neuropathologica, 1989 ; 77 : 379-390
18. Lang W, Probst A, Miklossy J, Deruaz JP, Pizzolato GP, Schaffner T, E Gessaga, Kleihues P. Pathologie des zentralen
      Nerven-systems bei Aids: Resultate einer kollaborativen Autopsiestudie aus der Schweiz. Schweiz Rundsch. Med. Prax.
      1990;79:562-568.
19. Lang W, Miklossy J, Deruaz J-R Pizzolato G, Probst A,. Schaffner T, Gessaga E, Kleihues P. Definition and incidence of 
      AIDS-associated CNS lesions. Prog AIDS Pathol, 1990;2:89-101.
20. Miklossy J, Kuntzer T, Bogousslavsky J, Regli F, Janzer RC. Meningovascular form of neuroborreliosis: Similarities
      between neuropathological findings in a case of Lyme disease and those occurring in tertiary neurosyphilis. Acta
      Neuropathol 1990;80:568-572.
21. Miklossy J, Van der Loos H. The long distance effects of brain lesions: A study of myelinated pathways in the human brain
      using polarizing and fluorescence microscopy. J Neuropathol Exp Neurol 1991;50:1-15.
22. Kuntzer T, Bogousslavsky J, Miklossy J, Steck AJ, Janzer RC, Regli F. Borrelia rhombencephalomyelopathy. Arch Neurol
      1991;48:832-836.
23. Miklossy J, Clarke S, Van der Loos H. The long distance effects of brain lesions: Visualization of axonal pathways and their 
      terminations in the human brain by the Nauta method. J Neuropathol Exp Neurol 1991;50:595-614.
24. von der Weid NX, de Crousaz H, Beck D, Deonna T, Miklossy J, Janzer RC. Acute fatal myeloencephalopathy after
      combined intrathecal chemotherapy in a child with acute lymphoblastic leukemia. Med Pediatr Oncol 1991;19:192-198.
25. Martin R, Bogousslavsky J, Miklossy J, Maeder P, Regli F, Janzer RC, Genton C. Floating thrombus in the innominate
      artery as a cause of cerebral infarction in young adults. Cerebrovascular Diseases 1992;2:177-181.
26. Darekar PM, Miklossy J. Application of fluorochromes for the visualization of lipids in human central and peripheral nervous
      tissue and muscle biopsies. Histo Journal. 1992; 11:29-37.
27. Uldry PA, Kuntzer T, Bogousslavsky J, Regli F, Miklossy J, Bille J, Francioli P, Janzer RC. Early symptoms and outcome
      of Listeria monocytogenes rhombencephalitis: 14 adult cases. J Neurol. 1993; 240:235-242.
28. Miklossy J. Alzheimer's disease - A spirochetosis? Neuroreport. 1993; 4:841-848 Press release
29. Miklossy J. Alzheimer's disease--a spirochetosis? (comment) Neuroreport. 1993; 4:849-850
30. Bogousslavsky J, Miklossy J. Smoothly progressive cerebral infarction over three weeks. Clinicopathological study in a
      patient with carotid occlusion. J Stroke and Cerebrovascular Diseases, 1993;3:61-64
31. Miklossy J. Alzheimer's disease - A spirochetosis? (Letter) Neuroreport. 1993; 4:1069
32. Ghika J, Miklossy J. Encephalopathie d'origine peu claire. Méd. Hyg. 1994; 52:815-825.
33. Miklossy J, Kasas S, Janzer RC, Ardizzoni F, Van der Loos H. Further morphological evidence for a spirochetal etiology
      of Alzheimer's Disease. NeuroReport: 1994:5:1201-1204.
34. Ghika-Schmid F, Kuntzer T, Chave JP, Miklossy J, Regli F. A wide range of neuromuscular disorders observed in 47 
      patients with human immunodeficiency virus infection. Range of neuromuscular involvement in 47 patients infected with the
      human immunodeficiency virus Schweiz. Med. Vochenschr. 1994;124:791-800.
35. Miklossy J, Gern L, Darekar P, Janzer RC, Van der Loos H. Senile plaques, neurofibrillary tangles and neuropil threads
      contain DNA? Journal of Spirochetal and Tick-borne Diseases (JSTD), 1995;2:1-5.
36. Meylan PR, Miklossy J, Iten A, Petignat C, Meuli R, Zufferey J and Sahli R. Myelitis due to varicella-zoster virus in an
      immunocompromised patient without a cutaneous rash. Clin. Infect. Dis., 1995;20:206-208.
37. Belichenko PV, Vogt Weisenhorn DM, Miklossy J, Celio M. Calretinin positive Cajal-Retzius cells persist in the adult
      human neocortex. NeuroReport, 1995, 6: 1869-1874.
38. Meylan P, Weber-Chappuis K, Miklossy J. Confrontation clinico-pathologique: Coma chez un patient éthylo-tabagique et
      diabétique. Méd et Hyg. 1996;54:624-34.
39. Miklossy J, Darekar P, Gern L, Janzer RC, Bosman FT. Bacterial peptidoglycan in neuritic plaques in Alzheimer's disease.
      Azheimer's Research, 1996; 2: 95-100.
40. Miklossy J. Alzheimer's disease and chronic inflammation. Ideggyogyaszati Szemle. 1996; 56:100-102
41. Kasas S, Thomson NH, Smith BL, Hansma PK, Miklossy J, Hansma PK. Biological applications of the AFM: From single
      molecules to organs. Int J Imaging Syst Technol 1997; 8:151-161.
42. Bogousslavsky J, Miklossy J, Encephalopathy, epilepsy and coma. Médecine et hygiène, 1997;55:773-779.
43. Belichenko PV, Miklossy J, Celio M. HIV-I induced destruction of neocortical extracellular matrix components in AIDS
      victims. Neurobiol. Dis. 1997; 4:301-310.
44. Miklossy J. Chronic inflammation and amyloidogenesis in Alzheimer's disease: Putative role of bacterial peptidoglycan, a
      potent inflammatory and amyloidogenic factor. Alzheimer's Rev. 1998;3:45-51.
45. Miklossy J, Lepori D, Genton C, Kraftsik R, Pillevuit O, Bosman FT. Curly fiber and tangle-like structures in the ependyma
      and the choroid plexus - A pathogenetic relationship with the cortical Alzheimer-type changes? J. Neuropathol. Exp.
      Neurol. 1998:57:104-114
46. Iten A, Chatelard P, Vuadens P, Miklossy J, Meuli R, Sahli R, Meylan PRA. Impact of cerebrospinal fluid on the
      management of HIV- infected patients with varicella-zoster virus infection of the central nervous system. J. NeuroVirology.
      1999;5:172-180.
47. Belichenko PV, Miklossy J, Belser B, Budka H, Celio MR. Early destruction of the extracellular matrix around
      parvalbumin-immunoreactive interneurons in Creutzfeldt-Jakob disease. Neurobiol Dis. 1999;6:269-279.
48. Suvà D, Favre I, Kraftsik R, Esteban M, Lobrinus A, Miklossy J. Involvement of primary motor cortex in Alzheimer's
      disease. J. Neuropathol Exp Neurol 1999; 58:1125-1134.
49. Miklossy J, Taddei K, Martins R, Escher G, Kraftsik R, Pillevuit O, Lepori D, Campiche M. Alzheimer disease: curly
      fibers and tangles in organs other than brain. J Neuropathol Exp Neurol. 1999;58:803-814.
50. Kovari E, Leuba G, Savioz A, Saini K, Anastasiu R, Miklossy J, Bouras C. Familial frontotemporal dementia with 
      ubiquitin inclusion bodies and without motor neuron disease. Acta Neuropathol (Berl). 2000;100:421-426.
51. Waeber G, Delplanque J, Bonny C, Mooser V, Steinmann M, Widmann C, Maillard A, Miklossy J, Dina C, H Hani E,
      Vionnet N, Nicod P, Boutin P, Froguel P. The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes.
      Nature Genetics 2000;24:291-295. Press release.
52. Mooser V, Helbecque N, Miklossy J, Marcovina SM, Nicod P, Amouyel Ph. Interactions between Apolipoprotein E and
      Apolipoprotein(a) in patients with Late-Onset Alzheimer disease. Ann Intern Med 2000;132:533-537. Press release.
53. Miklossy J, Kopniczky Z, Uske A, Delacretaz F, Chaubert P, Porchet F. Lymphoplasmacyte-rich meningioma with
      follicular infiltrates. Brain Pathol. 2000, on line: http://brainpathology.upmc.edu
54. Miklossy J, Kopniczky Z, Uske A, Delacretaz F, Chaubert P, Porchet F. April 2000: A 43 year old male with generalized 
      epileptic seizures. Brain Pathol. 2000;10:477-478.
55. de Freitas GR, Miklossy J, Christen-Zach S, Reichhart M, Bogousslavsky J. A CADASIL case with normal skin biopsy 
      and without mutations in exons 3 and 4 of the Notch3 gene. J Neurol Sci. 2001;193:43-47.
56. Michel P, Miklossy J, Kuntzer T. Peripheral axonal motor degeneration after spinal cord infarct.J Neurol Neurosurg
      Psychiatry. 2001;71:128.
57. Fonte J, Miklossy J, Atwood C, Martins RN. The severity of the cortical Alzheimer's type changes is Positively Correlated
      with Increased Beta Amyloid levels: esolubilization with Transition Metal Chelators. J Alzheimer Disease. 2001;3:209-219.
58. Ghika J, Villemure JG, Miklossy J, Temperli P, Pralong E, Christen-Zaech S, Pollo C, Maeder P, Bogousslavsky J, 
      Vingerhoets F. Postanoxic generalized dystonia improved by bilateral Voa thalamic deep brain stimulation. Neurology. 
      2002;58:311-313.
59. Miller LM., Dumas P, Jamin N, Teillaud JL, Miklossy J, Forro L. Combining IR Spectroscopy with Fluorescence Imaging
      in a Single Microscope: Biomedical Applications using a Synchrotron Infrared Source. Rev Sci Instr 2002;23:12-17.
60. Miller, LM, Dumas P, Jamin N, Teillaud JL Miklossy J & Forro L. Combining IR spectroscopy with fluorescence imaging in
      a single microscope: Biomedical applications using a synchrotron infrared source (PIN). Rev. Sci. Instr. 2002;73:1357-
      1360.
61. Taddei K, Fisher C,1 Laws SM, Martins G, Paton A,. Clarnette RM, Chung C, Brooks WS, Hallmayer J, Miklossy J, 
      Relkin N, St.George-Hyslop PH, Gandy SE, Martins RN. Association between presenilin-1 Glu318Gly mutation and 
      familial Alzheimer's Disease in the Australian population. Mol Psychiatry. 2002;7:776-81.Press release.
62. Suter OC, Sunthorn T, Kraftsik R, Straubel J, Darekar P, Khalili K, Miklossy J. Cerebral hypoperfusion generates cortical
      watershed microinfarcts in Alzheimer disease. Stroke, 2002;33:1986-92.
63. Christen-Zaech S, Kraftsik R, Pillevuit O, Kiraly M, Martins R, Khalili K, Miklossy J. Early olfactory involvement in 
      Alzheimer's disease. Can J Neurol Sci. 2003 Feb;30(1):20-5. Commentary: Weiss S. What can our nose tell us about
      possible treatments for Alzheimer's disease? Can J Neurol Sci. 2003;30:3. Editorial comment Can J Neurol Sci 
      2003;30:20-5.]
64. Helbecque N, Abderrhamani A, Meylan L, Riederer B, Mooser V, Miklossy J, Delplanque J, Boutin P, Nicod P, Haefliger
      J, Cottel D, Amouyel P, Froguel P, Waeber G. Islet-Brain 1/ C-Jun N-terminal Kinase Interacting protein-1 (IB1/JIP-1)
      promoter variant is associated with Alzheimer's disease. Molecular Psychiatry 2003;8:413-22.
65. Helbecque N, Abderrhamani A, Meylan L, Riederer B, Mooser V, Miklossy J, Delplanque J, Boutin P, Nicod P, Haefliger
      J, Cottel D, Amouyel P, Froguel P, Waeber G. Islet-Brain 1/ C-Jun N-terminal Kinase Interacting protein-1 (IB1/JIP-1)
      promoter variant is associated with Alzheimer's disease. Molecular Psychiatry 2003;8:363.
66. Miklossy J, Taddei K, Suva D, Verdile G, Fonte J, Fisher C, Gnjec A, Ghika J, Suard F, Mehta PD, McLean CA,
      Masters CL, Brooks WS, Martins RN. Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-
      onset Alzheimer's disease. Neurobiol Aging. 2003;24:655-662
67. Miklossy J. Cerebral hypoperfusion induces cortical watershed microinfarcts which may further aggravate cognitive decline
      in Alzheimer's disease. Neurol Res 2003; 25:605-610 (Review)
68. Helbecque N, Abderrhamani A, Meylan L, Riederer B, Mooser V, Miklossy J, Delplanque J, Boutin P, Nicod P, Haefliger
      JA, Cottel D, Amouyel P, Froguel P, Waeber G. Islet-brain 1/c-Jun N-terminal kinase interacting protein-1 (IB1/JIP-1)
      promoter variant is associated with Alzheimer's disease. Mol. Psychiatry. 2003, 8:947.
69. Del Valle L, Enam S, Lara C, Miklossy J, Khalili K, Gordon J. Primary central nervous system lymphoma expressing the
      human neurotropic polyomavirus, JC virus, genome. J. Virol. 2004;78:3462-3469.
70. von Gunten A, Miklossy J, Suva ML, Hof PR, Giannakopoulos P. Environmental reduplicative paramnesia in a case of
      atypical Alzheimer's disease. Neurology 2004; 251:750-752.
71. Zhang L, Zhang J, Lambert Q, Der CJ, Del Valle L, Miklossy J, Khalili K, Zhou Y, Pagano JS. Interferon regulatory factor
      7 is associated with Epstein-Barr virus-transformed central nervous system lymphoma and has oncogenic properties.
      J Virol. 2004; 78:12987-12995.
72. Verdile G, Gnjec A, Miklossy J, Fonte J, Veurink G, Bates K, Kakulas B, Mehta PD, Milward EA, Tan N, Lareu R, Lim
       D, Dharmarajan A, Martins RN. Protein markers for Alzheimer disease in the frontal cortex and cerebellum. Neurology.
       2004;63:1385-1392.
73. Miklossy J, Khalili K, Gern L, Ericson RL, Darekar P, Bolle L, Hurlimann J, Paster BJ. Borrelia burgdorferi persists in the 
      brain in chronic Lyme neuroborreliosis and may be associated with Alzheimer disease. J Alzheimer's Dis. 2004, 6 (6): 1-11.
74. Russmann H, Vingerhoets F, Miklossy J, Maeder P, Glatzel M, Aguzzi A, Bogousslavsky J. Sporadic Creutzfeldt-Jakob
      disease A comparison of pathological findings and diffusion weighted imaging. J Neurol. 2005;252:338-42. 
75. Miklossy J, Mackenzie IR, Dorovini-Zis K, Calne DB, Wszolek ZK, Klegeris A, McGeer PL. Severe vascular disturbance
      in a case of familial brain calcinosis. Acta Neuropathol (Berl). 2005 Jun 4; [Epub ahead of print]
76. von Gunten A, Miklossy J, Suva ML, Hof PR, Glannakopoulos P.Environmental reduplicative paramnesia in a case of
      atypical Alzheimer's disease. Neurocase. 2005;11:216-226.
77. Miklossy J, Doudet DD, Schwab C, Yu S, McGeer EG, McGeer PL. Role of ICAM-1 in persisting inflammation in
      Parkinson disease and MPTP monkeys. Exp Neurol. 2006;197:275-283. 
78. Miklossy J. Chronic inflammation and amyloidogenesis in Alzheimer's disease: The role of spirochetes. Thesis. Appeared in
      Collections (OEC) dspace.lib.unideb.hu, http://hdl.handle.net/2437/2648
79. Arai T, Miklossy J, Klegeris A, Guo JP, McGeer PL. Thrombin and prothrombin are expressed by neurons and glial cells
      and accumulate in neurofibrillary tangles in Alzheimer disease brain. J Neuropathol Exp Neurol. 2006;65:19-25.
80. Arai T, Akiyama H, J Miklossy, Guo JP, Klegeris A. Thrombin is a brain protease that processes tau. Neuropathology,
      2006; 26:A8.
81. Miklossy J, Kis A, Radenovic A, Miller L, Forro L, Martins R, Reiss K, Darbinian N, Darekar P, Mihaly L, Khalili K.
      Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes. Neurobiol Aging 2006;27:228-
      236. 
82. Miller L.M., Wang AQ, Telivala TP, Randy J, , Smith RJ, Lanzirotti A., Miklossy J. Synchrotron-based infrared and X-ray
      imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease. J Struct
      Biol. 2006;155:30-7. 
83. Wszolek ZK, Baba Y, Tsuboi Y, Uitti RJ, Strongoski AJ, Broderick DF, Baker MC, Hutton ML, Tsuboi Y, Allanson J,
      Carr J, Calne S, Stoessl AJ, Mackenzie I, Miklossy J, McGeer PL, Calne DB. Autosomal Dominant Familial Brain
      Calcinosis - Possible linkage to chromosome 8. Neurology. 2006;67:620-625.
84. Guo J, Arai T, Miklossy J, and McGeer PL. A-beta and tau form soluble complexes that may promote self aggregation of 
      both into the insoluble forms observed in Alzheimer disease. P.N.A.S. Proc Natl Acad Sci U S A. 2006 Feb 7;103
      (6):1953-1958. 
85. Miklossy J, Arai T, Guo JP, Klegeris A, Yu S, McGeer EG, McGeer PL. LRRK2 expression in normal and pathologic
      human brain and in human cell lines. J Neuropathol Exp Neurol. 2006;65:953-963.
86. Miklossy J, Rosemberg S, McGeer PL. Beta amyloid deposition in the atrophic form of general paresis. In: Alzheimer's
      Disease: New advances. Eds: Iqbal K, Winblad B, J Avila. Medimond. Intyernational Proceedings. Proceedings of the 10th
      International Congress on Alzheimer's Disease (ICAD) 2006; pp. 429-433.
87. McRae A, Martins RN, Fonte J, Kraftsik R, Hirt L, Miklossy J. Cerebrospinal fluid antimicroglial antibodies in Alzheimer
      disease: a putative marker of an ongoing inflammatory process. Exp Gerontol. 2007;42:355-363.
88. Miklossy J, Qing H, Guo JP, Yu S, Wszolek ZK, Calne D, McGeer EG, McGeer PL. Lrrk2 and chronic inflammation are
      linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation. Acta Neuropathol (Berl). 2007;114:243-
      254. 
89. Miklossy J, Martins RN. Chronic Inflammation and Amyloidogenesis in Alzheimer's Disease: Special issue: The emerging 
      role of infection. J. Alzheimer's Dis. 2008 ;13:357.
90. Miklossy J. Chronic inflammation and amyloidogenesis in Alzheimer's disease - role of spirochetes. J Alzheimer's Dis. 2008;
      13:381-391 (Review) Press release.
91. Weinberg G, Miklossy J. Iron and infection. J Alzheimer's Dis. 2008; 13:451-463. Review Press release 
92.  Xu D, Zhao L, Del Valle L, Miklossy J, Zhang L. Interferon regulatory factor 4 is involved in Epstein-Barr virus-mediated
       transformation of human B lymphocytes. J Virol. 2008; 82:6251-6258
93. Hashioka S, Miklossy J, Schwab S, Klegeris A, McGeer PL. Adhesion of exogenous human microglia and THP-1 cells to
      amyloid plaques of postmortem heimer's disease brain. J Alzheimer Dis 2008; 14: 345-352 
94. Miklossy J. Biology and neuropathology of dementia in syphilis and Lyme disease. Handb Clin Neurol 2008; 89:825-844.
95. Darbinian N, Cui J, Basile A, Del Valle L, Miklossy J, Sawaya BE, Amini S,Khalili K, and Gordon J. Negative regulation
      of APP gene expression by Pur-alpha. J Alzheimer's Dis 2008; 15: 71-82
96. Miklossy J, Martins RN, Darbinian N, Khalili K, McGeer PL. Type 2 diabetes: Local inflammation and direct effect of
      bacterial toxic products. Open Pathol J, 2008, 2: 86-95. (New journal)
97. Gnjec A, D'Costa KJ, Laws SM, Hedley R, Balakrishnan K, Taddei K, Martins G, Paton A, Verdile G, Gandy SE, Broe
      GA, Brooks WS, Bennett H, Piguet O, Price P, Miklossy J, Hallmayer J, McGeer PL, Martins RN. Association of alleles
      carried at TNFA -850 and BAT1 -22 with Alzheimer's disease. J Neuroinflammation. 2008; 5:36.
98. Miklossy J, Qing H, Radenovic A, Kis A, Vileno B, Làszló F, Miller L, Martins RN, Waeber G, Mooser V, Bosman F,
      Khalili K, Darbinian-Sarlissian N, McGeer PL. Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type
      2 diabetes. Neurobiol Aging. 2008, Oct 16, PMID: 18950899 [Epub ahead of print]
99. Miklossy J, Kasas S, Zurn A, McCall S, Yu S, McGeer PL. Persisting atypical and cystic forms of Borrelia burgdorferi
      and local inflammation in Lyme neuroborreliosis. J. Neuroinflammation. 2008, 5:40 Highly cited.
100. Miklossy J, Steele JC, Yu S, McCall S, Sandberg G, McGeer EG, McGeer PL. Enduring involvement of tau, beta-
        amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia
        complex of Guman (ALS/PDC). Acta Neuropathol 2008, 116:625-637 [Epub 2008, Oct 9].
101. Miklossy J. Emerging roles of pathogens in Alzheimer disease. Expert Rev Mol Med 2011 ; 13: e30.
102. Miklossy J. Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria.
        J Neuroinflammation. 2011, 4;8:90.


CHAPTERS IN BOOKS:

Lang W, Miklossy J, Deruaz JP, Pizzolato G, Probst A, Schaffner T,Gessaga E, Kleihues P. Definition and incidence of AIDS associated CNS lesions. In: Progress in AIDS Pathology, Vol. II H. Rotterdam (ed.), Field and Wood: Philadelphia, 1990;
Chapter 8, pp. 89-101
Miklossy J. The Geniculocalcarine Pathway in Man, and some Putative Visual areas Involved in Visuo-spatial Attention.In: The Functional Organization of Human Visual Cortex.(Eds: Gulyas B, Ottoson D, Roland PE) Pergamon Press, Oxford, 1993; pp. 123-136.
Miklossy J. The spirochetal etiology of Alzheimer's disease: A putative therapeutic approach. In: Alzheimer Disease: Therapeutic Strategies. Proceedings of the Third International Springfield Alzheimer Symposium. E. Giacobini and R. Becker Eds.) Birkhauser Boston Inc. 1994, Part I, pp41-48. 
Miklossy J. Biology and neuropathology of dementia in syphilis and Lyme disease. In: Handbook of Clinical Neurology, Dementias, Vol 89 (3rd series), Eds: C Duyckaerts, I Litvan, Elsevier, (Edinburgh, London, New York, Oxford, Philadelphia, St-Louis, Toronto, Sydney) Series Eds : MJ Aminoff, F Boller, DS Schwab), 2008, Volume 89, Chapter 72, pp. 825-844. 
Wszolek ZK, Zimprich A, Biskup S, Uitti RJ, Calne DB, Stoessl AJ, Imamura A, Farrer MJ, Miklossy J, Meitinger T, Gasser T, Dickson DW, McGeer PL. LRRK2 Leucine-Rich Repeat Kinase 2) gene on PARK8 locus in families with parkinsonism. In: Advances in Alzheimer's and Parkinson Disease. Insights, progress and perspectives (Advances in Behavioral Biology). Fisher A, Memo M, Stocchi F, Hanin I (Eds), Springer US, 2007;57: 75-89


PROCEEDINGS

Miklossy J. The Geniculocalcarine Pathway in Man, and some Putative Visual areas Involved in Visuo-spatial Attention. In: Functional Organization of the Human Visual Cortex. (Eds: B Gulyas, D Ottoson, PE Roland) Pergamon Press, Oxford, 1993; pp.123-136.
Miklossy J. The spirochetal etiology of Alzheimer's disease: A putative therapeutic approach. In: Alzheimer Disease: Therapeutic Strategies. Proceedings of the Third International Springfield Alzheimer Symposium. E. Giacobini and R. Becker Eds.) Birkhauser Boston Inc. 1994, Part I, pp 41-48.
Miklossy J. Chronic inflammation and amyloidogenesis in Alzheimer's disease: Putative role of bacterial peptidoglycan, a potent inflammatory and amyloidogenic factor. Alzheimer's Rev. 1998;3:45-51.
Miklossy J. Alzheimer's disease - a neurospirochetosis. Infectious diseases of the nervous system: Pathogenesis and worldwide impact, Paris, France. 10-13 September 2008. BMC Proceedings 2008, 2(S1): p43.


GUEST EDITOR - SPECIAL ISSUE
Chronic Inflammation and Amyloidogenesis in Alzheimer's Disease: Special issue: The Emerging Role of Infection, Guest Editors: Miklossy J, Martins RN, Journal of Alzheimer's Disease 2008; 13 (4) pp. 357-466.

 Publications of T. Arai

1. Arai T, Mizukami K, Matsuzaka H, Iwakuma A, Shiraishi H, Koizumi J: CNS changes in DRPLA with dementia and
    personality changes: CT, MR and SPECT findings. Jpn J Psychiatr Neurol 47: 105-110, 1993
2. Arai T, Mizukami K, Sasaki M, Tanaka Y, Shiraishi H, Horiguchi H, Ogata T: Clinicopathological study on a case of neuro-
    Behcet's disease: in special reference to MRI, SPECT and neuropathological findings. Jpn J Psychiatr Neurol 48: 77-84,
    1994
3.  Arai T, Ikeda K: Morphometrical comparison of neurofibrillary tangles and senile plaques in Alzheimer's disease and the
     senile dementia of Alzheimer type. Neuropathology 15: 21-26, 1995
4.  Ikeda K, Akiyama H, Kondo H, Arai T, Arai N, Yagishita S.: Numerous glial fibrillary tangles in oligodendroglia in cases of
     subacute sclerosing panencephalitis with neurofibrillary tangles. Neurosci Lett 194: 133-135, 1995
5.  Akiyama H, Kondo H, Ikeda K, Arai T, Kato M, McGeer PL: Immunohistochemical detection of coagulation factor XIIIa
     in postmortem human brain tissue. Neurosci Lett 202: 29-32, 1995
6.  Ikeda K, Akiyama H, Iritani S, Kase K, Arai T, Niizato K, Kuroki N, Kosaka K: Corticobasal degeneration with primary
     progressive aphasia and accentuated cortical lesion in superior temporal gyrus: case report and review. Acta Neuropathol
     92: 534-539, 1996
7.  Nishimura T, Ikeda K, Akiyama H, Arai T, Kondo H, Okochi M, Furiya Y, Mori H, Oda T, Kato M, Iseki E: Glial tau-
     positive structures lack the sequence encoded by exon 3 of the tau protein gene. Neurosci Lett 224: 169-172, 1997
8.  Ikeda K, Akiyama H, Arai T, Sahara N, Mori H, Usami M, Sakata M, Mizutani T, Wakabayashi K, Takahashi H : A
     subset of senile dementia with high incidence of the ApoE ε2 allele. Ann Neurol 41: 693-695, 1997
9.  Niizato K, Arai T, Kuroki, N, Kase K, Iritani, S, Ikeda K: Autopsy study of Alzheimer's disease brain pathology in
     schizophrenia. Schizophr Res 31: 177-184, 1998
10. Matsusaka H, Ikeda K, Akiyama H, Arai T, Inoue M, Yagishita S: Astrocytic pathology in progressive supranuclear palsy:
      significance for neuropathological diagnosis. Acta Neuropathol 96: 248-252, 1998
11. Ikeda K, Akiyama H, Arai T, Kondo H, Haga C, Iritani S, Tsuchiya K: Alz-50/Gallyas-positive lysosome-like intraneuronal
      granules in Alzheimer's disease and control brains. Neurosci Lett 258: 113-116, 1998
12. Ikeda K, Akiyama H, Arai T, Nishimura T: Glial tau pathology in neurodegenerative disease: their nature and comparison
      with neuronal tangles. Neurobiol Aging 19: S85-S91, 1998
13. Okochi M, Sahara N, Kametani F, Usami M, Arai T, Tanaka K, Ishii K, Yamamoto A, Mori H: Presenilin 1 cleavage is a
      universal event in human organs. Neurobiol Aging 19: S3-S10, 1998
14. Arai T, Ikeda K, Akiyama H, Haga C, Usami M, Sahara N, Iritani S, Mori H: A high incidence of apolipoprotein E 4
      allele in middle-aged non-demented subjects with cerebral amyloid ß protein deposits. Acta Neuropathol 97: 82-84, 1999
15. Arai T, Uéda K, Ikeda K, Akiyama H, Haga C, Kondo H, Kuroki N, Niizato K, Iritani S, Tsuchiya K: Argyrophilic glial
      inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for
      NACP/-synuclein. Neurosci Lett 259: 83-86, 1999
16. Ikeda K, Akiyama H, Arai T, Oda T, Kato M, Iseki E, Kosaka K, Wakabayashi K, Takahashi H: Clinical aspects of
      ‘senile dementia of the tangle type'-a subset of dementia in the senium separable from late-onset Alzheimer's disease. 
      Dement Geriatr Cogn Disord 10: 6-11, 1999
17.  Arai T, Akiyama H, Ikeda K, Kondo H, Mori H: Immunohistochemical localization of amyloid ß-protein with amino-
      terminal aspartate in the cerebral cortex of patients with Alzheimer's disease. Brain Res 823: 202-206, 1999
18. Wakabayashi K, Narisawa-Saito M, Iwakura Y, Arai T, Ikeda K, Takahashi H, Nawa H: Phenotypic down-regulation of
      glutamate receptor subunit GluR1 in Alzheimer's disease. Neurobiol Aging 20: 287-295, 1999
19. Ikeda K, Akiyama H, Arai T, Kondo H, Haga C, Tsuchiya K, Yamada S, Murayama S, Hori A: Neurons containing Alz-
      50-immunoreactive granules around the cerebral infarction: evidence for the lysosomal degradation of altered tau in human
      brain? Neurosci Lett 284: 187-189, 2000
20. Akiyama H, Arai T, Kondo H, Tanno E, Haga C, Ikeda K: Cell mediators of inflammation in the Alzheimer disease brain.
      Alzheimer Dis Assoc Discord 14: S47-S53, 2000
21. Ikeda K, Akiyama H, Arai T, Matsushita M, Tsuchiya K, Miyazaki H: Clinical aspects of argyrophilic grain disease. Clin
      Neuropathol 19:278-284 2000
22. Arai T, Ikeda K, Akiyama H, Shikamoto Y, Tsuchiya K, Yagishita S, Beach T, Rogers J, Schwab C, McGeer PL: Distinct
      isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and
      progressive supranuclear palsy. Acta Neuropathol 101: 167-173, 2001
23. Arai T, Ikeda K, Akiyama H, Tsuchiya K, Yagishita S, Takamatsu J: Intracellular processing of aggregated tau differs
      between corticobasal degeneration and progressive supranuclear palsy. Neuroreport 12: 935-938, 2001
24. Arai T, Ikeda K: Phenotypic heterogeneity of FTDP-17: implications for the differences of pathological phenotype among
      sporadic tauopathies. Neurobiol Aging 22: 127-129, 2001
25. Iseki E, Matsumura T, Marui W, Hino H, Odawara T, Sugiyama N, Suzuki K, Sawada H, Arai T, Kosaka K: Familial 
      frontotemporal dementia and parkinsonism with a novel N296H mutation in exon 10 of the tau gene and a widespread tau
      accumulation in the glial cells. Acta Neuropathol 102: 285-292, 2001
26. Ikeda K, Akiyama H, Arai T, Tsuchiya K: Pick-body-like inclusions in corticobasal degeneration differ from Pick bodies in
      Pick's disease. Acta Neuropathol 103: 115-118, 2002
27. Tsuchiya K, Nakayama H, Iritani S, Arai T, Niizato K, Haga C, Matsushita M, Ikeda K: Distribution of basal ganglia
       lesions in diffuse neurofibrillary tangles with calcification: a clinicopathological study of five autopsy cases.
       Acta Neuropathol 103: 555-564, 2002
28. Ikeda K, Akiyama H, Arai T, Ueno H, Tsuchiya K, Kosaka K: Morphometrical reappraisal of motor neuron system of
      Pick's disease and amyotrophic lateral sclerosis with dementia. Acta Neuropathol 104: 21-28, 2002
29. Odawara T, Iseki E, Kanai A, Arai T, Katsuragi T, Hino H, Furukawa Y, Kato M, Yamamoto T, Kosaka K:
      Clinicopathological study of two subtypes of Pick's disease in Japan. Dement Geriatr Cogn Disord 15: 19-25, 2003
30. Arai T, Ikeda K, Akiyama H, Tsuchiya K, Iritani S, Ishiguro K, Yagishita S, Oda T, Odawara T, Iseki E: Different
      immunoreactivities of the microtubule-binding region of tau and its molecular basis in brains from Alzheimer's disease, Pick's
      disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol 105: 489-498, 2003
31. Mochizuki A, Ueda Y, Komatsuzaki Y, Tsuchiya K, Arai T, Shoji S: Progressive supranuclear palsy with primary
      progressive aphasia-a clinicopathological study of autopsy case. Acta Neuropathol 105: 610-614, 2003
32. Arai T, Nonaka T, Hasegawa M, Akiyama H, Yoshida M, Hashizume Y, Tsuchiya K, Oda T, Ikeda K: Neuronal and glial
      inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62. Neurosci Lett 342:
      41-44, 2003
33. Blackshaw S, Eliasson MJ, Sawa A, Watkins CC, Krug D, Gupta A, Arai T, Ferrante RJ, Snyder SH: Species, strain and
      developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-
      dependent synaptic plasticity. Neuroscience 119: 979-90, 2003
34. Oshima K, Tsuchiya K, Arai T, Akiyama H, Iritani S, Niizato K, Matsushita M, Ikeda K: Atypical late-onset dementia 
      characterized by limbic degeneration with coiled bodies and argyrophilic threads. Clin Neuropathol 22: 296-303, 2003
35. Katsuse O, Iseki E, Arai T, Akiyama H, Togo T, Uchikado H, Kato M, de Silva R, Lees A, Kosaka K: 4-Repeat
      tauopathy sharing pathological and biochemical features of corticobasal degeneration and progressive supranuclear palsy. 
      Acta Neuropathol 106: 251-260, 2003
36. Arai T, Akiyama H, Tsuchiya K, Iritani S, Ishiguro K, Yagishita S, Oda T, Odawara T, Iseki E, Ikeda K: Tau pathology of
      sporadic tauopathies. Molecular Neurobiology of Alzheimer's disease and related disorders, Basel, Karger, pp52-61, 2004
37. Uchihara T, Nakamura A, Arai T, Ikeda K, Tsuchiya K: Microglial tau undergoes phosphorylation-independent
      modification after ischemia. Glia 45: 180-187, 2004
38. Akiyama H, Kondo H, Arai T, Ikeda K, Schwab C, McGeer PL: Expression of BRI, the normal precursor of the amyloid
      protein of familial British dementia, in human brain. Acta Neuropathol 107: 53-58, 2004
39. Arai T, Ikeda K, Akiyama H, Nonaka T, Hasegawa M, Ishiguro K, Iritani S, Tsuchiya K, Iseki E, Yagishita S, Oda T,
      Mochizuki A: Identification of amino-terminally cleaved tau fragments that distinguish progressive supranuclear palsy from
      corticobasal degeneration. Ann Neurol 55: 72-79, 2004
40. Arai T, Guo JP, McGeer PL: Proteolysis of non-phosphorylated and phosphorylated tau by thrombin. J Biol Chem 280:
      5145-5153, 2005
41. Tsuchiya K, Nakayama H, Haga C, Oshima K, Niizato K, Arai T, Matsushita M, Akiyama H: Distribution of basal ganglia
      lesions in diffuse neurofibrillary tangles with calcification: a clinicopathological study of five autopsy cases. Acta Neuropathol
      110: 57-68, 2005
42. Shibuya-Tayoshi S, Tsuchiya K, Seki Y, Arai T, Kasahara T: Presenile dementia mimicking Pick's disease: An autopsy case
      of localized amygdala degeneration with character change and emotional disorder. Neuropathology 25: 235-240, 2005
43. Arai T, Miklossy J, Klegeris A, Guo JP, McGeer PL: Thrombin and prothrombin are expressed by neurons and glial cells
      and accumulate in neurofibrillary tangles in Alzheimer's disease brain. J Neuropathol Exp Neurol 65: 19-25, 2006
44. Guo JP, Arai T, Miklossy J, McGeer PL: Aß and tau form soluble complexes that may promote self aggregation of both into
      the insoluble forms observed in Alzheimer disease. Proc Natl Acad Sci USA 103: 1953-1958, 2006
45. Iritani S, Tohgi M, Arai T, Ikeda K: Immunohistochemical study of the serotonergic system in animal model of the mood
      disorder. Exp Neurol 201: 60-65, 2006
46. Miklossy J, Arai T, Guo JP, Klegeris A, Yu S, McGeer E, McGeer PL: LRRK2 expression in normal and pathological
      human brain and in human cell lines. J Neuropathol Exp Neurol 65: 953-963, 2006
47. Yokota O, Tsuchiya K, Oda T, Ishihara T, de Silva R, Lees AJ, Arai T, Uchihara T, Ishizu H, Kuroda S, Akiyama H:
      Amyotrophic lateral sclerosis with dementia: an autopsy case showing many Bunina bodies, tau-positive neuronal and
      astrocytic plaque-like pathologies, and pallido-nigral degeneration. Acta Neuropathol 112: 633-645, 2006
48. Oda T, Tsuchiya K, Arai T, Togo T, Uchikado H, de Silva R, Lees A, Akiyama H, Haga C, Ikeda K, Kato M, Kato Y,
      Hara T, Onaya M, Hori K, Teramoto H, Tominaga I: Pick's disease with Pick bodies: An autopsy case showing
      degeneration of the pontine nucleus, dentate nucleus, Clarke's column, and lower motor neuron. Neuropathology 27:
      81-89, 2007
49. Hasegawa M, Arai T, Akiyama H, Nonaka T, Mori H, Hashimoto T, Yamazaki M, Oyanagi K: TDP-43 is deposited in
      the Guam parkinsonism-dementia complex brains. Brain 130: 1386-1394, 2007
50. Ishii A, Nonaka T, Taniguchi S, Saito T, Arai T, Mann D, Iwatsubo T, Hisanaga S, Goedert M, Hasegawa M: Casein
      kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-
      synucleinopathies. FEBS Lett 581: 4711-4717, 2007
51. Hasegawa M, Arai T, Nonaka T, Kametani F, Nonaka T, Yoshida M, Hashizume Y, Beach TG, Buratti E, Baralle F,
      Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H: Phosphorylated TDP-43 in frontotemporal lobar degeneration and
      ALS. Ann Neurol 64: 60-70, 2008
52. Inukai Y, Nonaka T, Arai T, Yoshida M, Hashizume Y, Beach TG, Buratti E, Baralle F, Akiyama H, Hisanaga S,
      Hasegawa M: Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. FEBS Lett 582: 2899-2904,
      2008
53. Iritani S, Tsuchiya K, Arai T, Akiyama H, Ikeda K: An atypical autopsy case of Lewy Body disease with clinically
      diagnosed major depression: A clinical, radiological and pathological study. Neuropathology 652-659, 2008
54. Kobayashi Z, Tsuchiya K, Takahashi M, Yokota O, Sasaki A, Bhunchet E, Arai T, Akiyama H, Kamoshita M, Kotera M,
      Mizusawa H: An autopsy case of chronic active Epstein-Barr virus infection (CAEBV): distribution of central nervous 
      system (CNS) lesions. J Neurol Sci 275: 170-177, 2008
55. Schwab C, Arai T, Hasegawa M, Yu S, McGeer PL: Colocalization of TDP-43 and huntingtin in inclusions of Huntington's
      disease. J Neuropathol Exp Neurol 67: 1159-1165, 2008
56. Kobayashi Z, Tsuchiya K, Machida A, Goto J, Yokota O, Miake H, Watabiki S, Taki K, Ishizu H, Haga C, Arai T,
      Akiyama H, Mizusawa H: Metastatic CNS lymphoma presenting with periventricular dissemination- MRI and
      neuropathological findings in an autopsy case. J Neurol Sci 277: 109-113, 2009
57. Fujishiro H, Uchikado H, Arai T, Hasegawa M, Akiyama H, Yokota O, Tsuchiya K, Togo T, Iseki E, Hirayasu Y:
      Accumulation of phosphorylated TDP-43 in brains of patients with argyrophilic grain disease. Acta Neuropathol, in press
58. Nonaka T, Arai T, Buratti E, Baralle F, Akiyama H, Hasegawa M: Phosphorylated and ubiquitinated TDP-43 pathological
      inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells. in press
59. Arai T, Mackenzie IRA, Hasegawa M, Nonaka T, Niizato K, Tsuchiya K, Iritani S, Onaya M, Akiyama H: Phosphorylated
      TDP-43 in Alzheimer's disease and dementia with Lewy bodies. Acta Neuropathol, in press


Publications of John C Steele

53.  Williams DR, Lees AJ, Wherrett JR, Steele JC. J. Clifford Richardson and 50 years of progressive
       supranuclear palsy. Neurology 2008:70;566-573.
52. Caparros-Lefebvre D, Steele J, Kotake Y, Ohta S. Geographic isolates of atypical parkinsonism and
      tauopathy in the tropics: Possible synergy of neurotoxins. Clinical/Scientific notes. Movement Disorders
      Journal November 2006 21.

51. Steele JC. The Parkinsonism-dementia complex of Guam . Movement Disorders Journal March 2005
      20 suppl12 S99-107.

50. Caparros-Lefebvre D, Steele J. Atypical parkinsonism on Guadeloupe, comparison with  the parkinsonism-
       dementia complex of Guam , and environmental toxic hypotheses.  Environmental Toxicology and
       Pharmacology 2005 19 407-413.

49.  Evans W, Fung HC, Steele J, Eerola J, Tienari P, Pittman A, deSilva R, Myers A, Wavrant-DeVrieze F, Singelton A,
       Hardy J. The tau H2 haplotype is almost exclusively Caucasian in origin. Neuroscience Letters 2004

48. Morris HR, Steele JC, Crook R, Wavrant de-Vrieze F, Omstead L, Gwinn-Hardy K, Wood NW, Farrer M,
      Lees AJ, Siddique T, Hardy J, Perez-Tur J. Genome wide analysis of the parkinsonism-dementia complex
      of Guam. Arch Neurolo 2004 61 1880-1897.

47. Murch SJ, Cox PA, Banack SA, Steele JC, Sacks QW. Occurrence of b-methylamino-L-alanine (BMAA)
      in ALS/PDC patients from Guam . Accepted for publication in Acta Neurol Scand 2004 April.

46. Steele JC, Caparros-Lefebvre D, Lees AJ, Sacks OW. Progressive supranuclear palsy and its relation
      to pacific foci of the parkinsonism-dementia complex and Guadeloupean parkinsonism. Parkinsonism
      and Related Disorders 2002 9 39-54.

45. Morris HR, Al-Sarrah S, Schwab C, Gwinn-Hardy K, Perez-Tur J, Wood NW, Hardy J, Lees AJ, McGeer
      PL, Damiel SE, Steele JC. A clinical and pathological study of motor neurone disease on Guam .
      Brain 2001 124 2215-2222.

44. Perez-Tur J, Buee L, Morris HR, Waring S, Onstead L, Wavrant-De Vrieze F, Crook R, Buee-Scherrer V,
      Hof PR, Petersen R, McGeer PL, Delacourte A, Hutton M, Siddique T, Ahlskog JE, Hardy J, Steele JC.
      The lesion in neurodegenerative diseases of Guam is not in the TAU gene. Neurology 1999 53 411-413.

43. Schwab, C., Steele, J. C., McGeer, P.L.: Pyramidal neuron loss is matched by increasing numbers of
      ghost tangles in Guam parkinson‑dementia. Acta Neuropathologica. 1998 96(4) 409-416.

42. McGeer, P.L., Schwab, C., McGeer, E.G., Haddock, R.L., Steele, J. C.: Familial nature and continuing
      morbitity of the amyotrophic lateral sclerosis‑parkinsonism dementia complex of Guam . Neurology 1997
      49 400‑409.

41. Schwab, C., Steele, J. C., McGeer, P.L.: Dystrophic neurites areassociated with the majority of early stage
      extracellularneurofibrillary tangles in parkinsonism‑dementia complex of Guam. Acta Neuropathologica
      1997 94 486‑492.

40. Schwab C, Steele JC, McGeer PL. Neurofibrillary tangles of Guam parkinsonism-dementia are associated
       with reactive microglia and complement proteins. Brain Research 1996 707 196-205.

39. Yasuhara O, Schwab C, Matsuo A, Kim SU, Steele JC, Akiguchi I, Kimura J, McGeer EG, McGeer PL.
       Midkine-like immunoreactivity in extracellular neurofibrillary tangles in brains of patients with parkinsonism-
       dementia complex of Guam. Neuroscience Letters 1996 205 107-110.

38. Schwab C, Steele JC, Akiyama H, McGeer PL Distinct distribution of ApoE and b-amyloid immunoreactivity
       in the hippocampus of the parkinson-dementia complex of Guam..
Acta Neuropathol 1996 92 378-385.

37. Schwab C, Steele JC, Akiyama H, McGeer E, McGeer PL. Relationship of amyloid b/A4 protein to
       the neurofibrillary tangles in Guamanian parkinsonism-dementia. Acta Neuropathol 1995 90 287-298.
 
36. Steele JC, Williams DB. Calcium and aluminum in the Chamorro diet: Unlikely causes of Alzheimer-type
      neurofibrillary degeneration on Guam . Motor Neuron Disease, Biology and Management, eds Swash and
      Leigh. Springer-Verlag London 1995 189-198.

35. Steele JC. Alternating hemiplegia of childhood: A historical introduction and an account of the earliest
      observations. Introductory Chapter in Alternating Hemiplegia of Childhood, eds Vigevano,
      Aicardi, Andermann. Raven Press 1995 xx1-xx111.

34. Steele  JC. Historical notes. Progressive supranuclear palsy: Diagnosis, pathology and therapy, eds Tolosa,
       Duvoisin and Cruz-Sanchez. Journal of Neural Transmission 1994 Supplementum 42 3-14.

33. Steele JC. Guam seaweed poisoning: Common marine toxins. Micronesica 1993 26 11-18.

32. Glosser G, Wolfe N, Albert ML, Lavine L, Steele JC, Calne DB, Schoenberg BS. Cross-cultural cognitive
      examination: Validation of a dementia screening instrument for neuroepidemiological research.
      JAGS 1993 41 931-939.

31. Campbell RJ, Steele JC, Cox TA, Loerzel AJ, Belli M, Belli DD, Kurland LT. Pathological findings in
      the retinal pigment epitheliopathy associated with the amyotrophic lateral sclerosis/parkinsonism-dementia
      complex of Guam . Ophthalmology 1993 100 1 37-42.

30. Hanlon SD, Steele JC, An unusual retinal pigment epitheliopathy endemic to the island of Guam.
      Optometry and Visual Science 1993 70 10 854-859.
 
29. Steele JC. Introduction. Chapter 1 Progressive supranuclear palsy: Clinical and research approaches, eds  Agid
      and  Litman. Oxford University Press 1992
 
28. Armon C, Kurland LT, Smith G, Steele JC. Sporadic and Western Pacific amyotrophic lateral sclerosis:
       Epidemiological implications. Chapter 5 in Handbook of ALS, ed Smith. Marcel Dekker NY  1992

27. Perl DP, Steele JC, Loerzel A, Kurland LT. Amyotrophic lateral sclerosis-parkinsonism dementia complex
      of Guam as a model of Alzheimer's disease. In Alzheimer's Disease: Basic mechanisms, diagnosis
      and therapeutic strategies. Edited by K. Iqbal, D. R. C. McLachlan, B. Winblad and H. M. Wisniewski. 1991
      John Wiley and Sons Ltd.

26. Doty RL, Perl DP, Steele JC, Chen KM, Pierce JD, Reyes P, Kurland LT. Odor identification deficit of the
      parkinsonism-dementia complex of Guam: Equivalence to that of Alzheimer's and idiopathic Parkinson's
      disease. Neurology 1991 41(Suppl2) 77-81.

25. Lavine L, Steele JC, Wolfe N, Calne DB, O'Brien PC, Williams DB, Kurland LT, Schoenberg BS.
     Amyotrophic lateral sclerosis/parkinsonism-dementia complex in southern Guam : Is it disappearing?
     Chapter 23 Advances in Neurology, Vol 56: Amyotrophic lateral sclerosis and other motor neuron diseases,
     ed Rowland. Raven Press 1991.

24. Steele J, Quinata-Guzman T. The Chamorro diet: An unlikely cause of neurofibrillary degeneration on Guam .
      Chapter 12 Amyotrophic lateral sclerosis: New advances in toxicology and epidemiology, ed Rose and
      Norris. Smith-Gordon and Co UK 1990.

23. Bergeron C, Steele JC. Guam parkinsonism-dementia complex and amyotrophic lateral sclerosis. A clinico-
      pathological study of seven cases. Chapter 13 Amyotrophic lateral sclerosis: New advances in toxicology
      and epidemiology, ed Rose and Norris. Smith-Gordon and Co UK 1990.

22. Perl DP, Steele JC, Purohit D. Amyotrophic lateral sclerosis in a Caucasian mainland US-born long term
      resident on Guam- a case report including neuropathologic examination. Chapter 14 Amyotrophic lateral
      sclerosis: New advances in toxicology and epidemiology, ed Rose and Norris. Smith-Gordon and Co UK
     1990.

21. Steele J, Guzman TQ, Driver MG, Zolan W, Heitz LF, Kilmer FH, Parker CM, Standal BR, Pobutsky AM,
      Crapper McLachlan D. Nutritional factors in ALS on Guam:  Observations from Umatac.  Chapter in
      Amyotrophic lateral sclerosis:  Current clinical and pathophysiological evidence for differences in etiology,
      ed Hudson, University of Toronto Press 1990 193-223.

20. Duncan MW, Steele JC, Kopin IJ, Markey SP. 2-amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: An
      unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam. Neurology 1990 40 5 767-772

19. Snow BJ, Peppard RF, Guttman M, Okada J, Wayne Martin WR, Steele JC, Eisen A, Carr G, Schoenberg
      B, Calne D. Positron emission tomographic scanning demonstrates a presynaptic dopaminergic lesion in
      lytico-bodig: The amyotrophic lateral sclerosis-parkinsonism-dementia complex of Guam. Arch Neurol 1990
      47 870-874.

18. Peppard RF, Martin WRW, Guttman M, Grochoswki E, Okada J, McGeer PL, Carr GD, Phillips AG, Steele
      JC, Tsui JKC, Calne DB. Cerebral glucose metabolism in Parkinson's disease and the PD complex of
      Guam . Chapter 53 445-452.

17. Cox T, McDarby J, Lavine L, Steele J, Calne D. A retinopathy on Guam with high prevalence in lytico-bodig.
      Ophthalmology 1989 96 12 1731-1735.
16. Steele JC, Ballendorf DA. Federico: A health hazard? Guam and Micronesia 1989 2 4-11.
15. Crapper McLachlan D, McLachlan C, Krishnan B, Krishnan S, Dalton A, Steele J. Aluminum and calcium in
      Guam, Palau and Jamaica:  Implications for amyotrophic lateral sclerosis and parkinsonism-dementia
      syndromes on Guam.  Environmental Geochemistry and Health 1989 112 45-53.

14. Lepore F, Steele J, Cox T, Tillson G, Calne D, Duvoisin R. Supranuclear disturbances of ocular mobility in
       lytico-bodig.  Neurology  1988 38 1849-53.

13. Steele J, Guzman T.  Amyotrophic lateral sclerosis and parkinsonism-dementia in Guam :  An Update. 
      Recent developments in Parkinson's disease Volume II eds Fahn, Marsden, Calne, Goldstein, Macmillan
      Health Care Information 1987 53-57.

12. Steele J, Guzman T. Observations about amyotrophic lateral sclerosis and the parkinsonism-dementia
      complex of Guam with regard to epidemiology and etiology. Can J Neurol Sci 1987 14 3 (supplement)358-
      362.

11. Steele J. Micronesia :  Health status and neurological diseases.  Amyotrophic lateral sclerosis in Asia and
       Oceania, eds Chen and Yase, National Taiwan University 1984 173-183.

10. Steele J. Medical diseases of the American Pacific. Office of the Dean, University of Hawaii Medical School
       1983 1-217.

 
9. Steele J. Progressive supranuclear palsy.  Handbook of Clinical Neurology, eds Vinken and Bruyn 1975 22
      217-229.

 
8. Steele J. Progressive supranuclear palsy.  Brain 1972 95 693-704. 
 
7. Steele JC, Richardson JC, Olszewski J. Progressive supranuclear palsy; A heterogeneous degeneration
      involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal
      dystonia and dementia. Arch Neurol 1964 10 333-359.

  6. Watson P, Steele JC. Paroxysmal dysequilibrium in the migraine syndrome of childhood. Arch Otolaryngol
      1974 99 177-179.

 
5. Hachinski VC, Porchawka J, Steele JC. Visual symptoms in the migraine syndrome. Neurology 1973 23
      570-579.

 
4. Steele JC, Gladstone RM, Thanasophon S, Fleming PC. Mycoplasma pneumoniae as a determinant of the
      Guillain-Barre syndrome. Lancet 1972 II 710-714.

 
3. Steele JC, Gladstone RM, Thanasophon S, Fleming PC. Acute cerebellar ataxia and concomitant infection with
      Mycoplasma pneumoniae. J Pediatr 1972 80 467-469.   
  2. Verret S, Steele JC. Alternating hemiplegia in childhood: A report of eight patients with complicated
       migraine beginning in infancy. Pediatrics 1971 47 675-680.
 
 1. Steele JC, Vasuvat A. Recurrent multiple cranial nerve palsies: A distinctive syndrome of cranial
      polyneuropathy. J  Neurol Neurosurg Psychiat 1970 33 828-832.